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Cardiovascular disease is the leading cause of death in developed countries, but is quickly becoming an epidemic in such well-populated countries as China, India, and other developing nations. Cardiovascular research is the key to the prevention, diagnosis, and management of cardiovascular disease. Vigorous and cross-disciplinary approaches are required for successful card- vascular research. As the boundaries between different scientific disciplines, particularly in the life sciences, are weakening and disappearing, a successful investigator needs to be competent in many different areas, including genetics, cell biology, biochemistry, physiology, and structural biology. The newly developed field of molecular medicine is a cross-disciplinary science that seeks to comprehend disease causes and mechanisms at the molecular level, and to apply this basic research to the prevention, diagnosis, and treatment of diseases and disorders. This volume in the Methods in Molecular Medicine series, C- diovascular Disease, provides comprehensive coverage of both basic and the most advanced approaches to the study and characterization of cardiovascular disease. These methods will advance knowledge of the mechanisms, diagnoses, and treatments of cardiovascular disease. Cardiovascular Disease is a timely volume in which the theory and pr- ciples of each method are described in the Introduction section, followed by a detailed description of the materials and equipment needed, and step-by-step protocols for successful execution of the method. A notes section provides advice for potential problems, any modifications, and alternative methods.

Cardiology. --- Heart --- Internal medicine --- Diseases

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In an article for Wired Magazine in 2006, Jeff Howe defined crowdsourcing as an idea for outsourcing a task that is traditionally performed by a single employee to a large group of people in the form of an open call. Since then, by modifying crowdsourcing into different forms, some of the most successful new companies on the market have used this idea to make people’s lives easier and better. On the other hand, software testing has long been recognized as a time-consuming and expensive activity. Mobile application testing is especially difficult, largely due to compatibility issues: a mobile application must work on devices with different operating systems (e.g. iOS, Android), manufacturers (e.g. Huawei, Samsung) and keypad types (e.g. virtual keypad, hard keypad). One cannot be 100% sure that, just because a tested application works well on one device, it will run smoothly on all others. Crowdsourced testing is an emerging paradigm that can improve the cost-effectiveness of software testing and accelerate the process, especially for mobile applications. It entrusts testing tasks to online crowdworkers whose diverse testing devices/contexts, experience, and skill sets can significantly contribute to more reliable, cost-effective and efficient testing results. It has already been adopted by many software organizations, including Google, Facebook, Amazon and Microsoft. This book provides an intelligent overview of crowdsourced testing research and practice. It employs machine learning, data mining, and deep learning techniques to process the data generated during the crowdsourced testing process, to facilitate the management of crowdsourced testing, and to improve the quality of crowdsourced testing.

Computers. --- Automatic computers --- Automatic data processors --- Computer hardware --- Computing machines (Computers) --- Electronic brains --- Electronic calculating-machines --- Electronic computers --- Hardware, Computer --- Computer systems --- Cybernetics --- Machine theory --- Calculators --- Cyberspace --- Computer programs --- Software engineering --- Software Testing. --- Software Management. --- Testing. --- Management. --- Computer program testing --- Debugging in computer science --- Programari --- Assaigs (Tecnologia)

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Thereare richtheories and designs for generalcontrolsystems,but usually, they will not lead to PID controllers. Noting that the PID controller has been the most popular one in industry for over ?fty years, we will con?ne our discussion hereto PIDcontrolonly. PID controlhasbeenanimportantresearchtopicsince 1950’s, and causes remarkable activities for the last two decades. Most of the existing works have been on the single variable PID control and its theory and design are well established, understood and practically applied. However, most industrial processes are of multivariable nature. It is not rare that the overall multivariable PID control system could fail although each PID loop may work well. Thus,demandforaddressingmultivariableinteractionsishighforsuccessful applicationofPIDcontrolinmultivariableprocessesanditisevidentfrommajor leading control companies who all rankedthe couplings of multivariable systems as the principal common problem in industry. There have been studies on PID control for multivariable processes and they provide some useful design tools for certaincases. But itis notedthat the existing worksaremainlyfor decentralized form of PID control and based on ad hoc methodologies. Obvious, multivariable PID control is much less understood and developed in comparison with the single variable case and actual need for industrial applications. Better theory and design have to be established for multivariable PID control to reach the same maturity and popularity as the single variable case. The present monograph puts together, in a single volume, a fairly comp- hensive, up-to-date and detailed treatment of PID control for multivariable p- cesses, from paring, gain and phase margins, to various design methods and applications.

PID controllers. --- MIMO systems. --- Robust control. --- Régulateurs PID --- Systèmes à entrées multiples et à sorties multiples --- Commande robuste --- PID controllers --- MIMO systems --- Robust control --- Mechanical Engineering - General --- Mechanical Engineering --- Engineering & Applied Sciences --- Robustness (Control systems) --- Multiple input-multiple output systems --- Proportional Integral-Derivative controllers --- Proportional-plus-Integral-plus-Derivative controllers --- Engineering. --- System theory. --- Control engineering. --- Robotics. --- Mechatronics. --- Control, Robotics, Mechatronics. --- Systems Theory, Control. --- Automatic control --- Wireless communication systems --- Systems, Theory of --- Systems science --- Science --- Philosophy --- Systems theory. --- Mechanical engineering --- Microelectronics --- Microelectromechanical systems --- Automation --- Machine theory --- Control engineering --- Control equipment --- Control theory --- Engineering instruments --- Programmable controllers

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Classical mechanics. Field theory --- Applied physical engineering --- Engineering sciences. Technology --- Computer science --- procesautomatisering --- informatica --- systeemtheorie --- systeembeheer --- dynamica --- regeltechniek

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This volume contains papers presented at the first joint conference of the Software Pr- ess Workshop and the International Workshop on Software Process Simulation and Modeling (SPW/ProSim 2006) held in Shanghai, P.R. China, on May 20-21, 2006. The theme of SPW/ProSim 2006 was “Software Process Change – Meeting the Challenge.” Software developers are under ever-increasing pressure to deliver their products more quickly and with higher levels of quality. These demands are set in a dynamic context of frequently changing technologies, limited resources and globally distributed development teams. At the same time, global competition is forcing - ganizations that develop software to cut costs by rationalizing processes, outsourcing part or all of their activities, reusing existing software in new or modified applications and evolving existing systems to meet new needs, while still minimizing the risk of projects failing to deliver. To address these difficulties, new or modified processes are emerging, including agile methods and plan-based product line development. Open Source, COTS and community-developed software are becoming more popular. Outsourcing coupled with 24/7 development demands well-defined processes and interfaces to support the coordination of organizationally and geographically separated teams. All of these challenges combine to increase demands on the efficiency and effectiveness of so- ware processes.

Computer software --- Logiciels d'ordinateurs --- Logiciels --- Congresses. --- Development --- Congrès --- Développement --- Computer Science --- Engineering & Applied Sciences --- Information Technology --- Software Engineering --- Computer science. --- Software engineering. --- Computer programming. --- Application software. --- Computers and civilization. --- Management information systems. --- Computer Science. --- Software Engineering/Programming and Operating Systems. --- Software Engineering. --- Management of Computing and Information Systems. --- Computer Appl. in Administrative Data Processing. --- Computers and Society. --- Programming Techniques. --- Computer-based information systems --- EIS (Information systems) --- Executive information systems --- MIS (Information systems) --- Sociotechnical systems --- Information resources management --- Management --- Civilization and computers --- Civilization --- Application computer programs --- Application computer software --- Applications software --- Apps (Computer software) --- Computers --- Electronic computer programming --- Electronic data processing --- Electronic digital computers --- Programming (Electronic computers) --- Coding theory --- Computer software engineering --- Engineering --- Informatics --- Science --- Communication systems --- Programming --- Information Systems. --- Information systems.