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In this book recent developments in dehydrogenation reactions catalyzed by 3d-metals are discussed. With continue efforts to develop sustainable chemical production the discovery of new catalysts and catalytic procedures for (de)hydrogenation reactions are a subject of great interest to the chemistry community. Additionally, (de)hydrogenation reactions enable the creation of closed-loop production cycles that support a circular economy. The chapters presented include the synthesis of heterocycles and tandem-multicomponent (three or more) reactions through dehydrogenative strategy, as well as the conversion of ethanol to n-butanol, higher oxidized hydrocarbons like acids, ester, amides from alcohols, α-alkylation of amines, ketones, and amides with alcohols and mechanistic understanding of dehydrogenation reactions with high-valent metals. With contributions from experts in the field, the book is a valuable resource for scholars working in the field of organometallic chemistry, catalysis, medicinal chemistry, as well as researchers in the industry.
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Basic Sciences. Chemistry --- Organic compounds --- Organic Chemistry. --- Industrial applications. --- Organic chemistry --- Industrial chemistry
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Organic chemistry --- Chemistry --- General biophysics --- biologische materialen --- organische chemie --- chemie
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Organic chemistry --- General biophysics --- biologische materialen --- organische chemie
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This book comprehensively covers the fundamentals and latest advancements in the area of click chemistry. It discusses notable applications of click chemistry in various emerging areas ranging from chemical biology to catalysis and from medicinal chemistry to material sciences. Various topics covered in this book are catalysis in regioselectivity in click chemistry, organocatalysis in triazole synthesis, Bertozzi’s Bioorthogonal Concept, photo-triggered click chemistry, SuFEx Click, Thiol-Ene Click, MCR Click, Intramolecular Click Chemistry, synthesis of diverse triazoles and their applications, Click's Post Functionalization, etc. The book is a valuable reference for beginners, researchers and professionals interested in sustainable click concept and its diverse applications in allied fields.
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This book provides an overview of the new plant natural product skeletons discovered from 1999 to 2021. It categorizes these natural products by providing their names, source distributions, structural types, structure characteristics, and bioactivities. A total of 1373 plant products in 99 families are presented, which cover 36 different structure types within the Hypericaceae family of which the majority are alkaloid structures. In addition, it presents the biological profiling in the last 23 years by summarizing the biological activities and potential disadvantages. The new natural products skeleton presented are unprecedented structural scaffolds and could bring new opportunities for biological/pharmaceutical areas and provide new structure templates for synthetic chemists. This book helps readers gain in-depth insight into the past and recent trends of natural products; it also assists those interested in assessing the potential biological function of the natural products.
Natural products. --- Chemistry. --- Biomaterials. --- Chemistry, Organic. --- Natural Products. --- Chemical Synthesis. --- Plant Materials. --- Organic Chemistry. --- Sesquiterpenes.
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This book is an introductory text for graduate students, researchers in industries, and those who are just beginning to work on organic electronics materials, devices and their applications. The book includes mainly fundamental principles and theories for understanding organic electronics materials and devices, but also provides information about state-of-the-art technologies, applications and future prospects. These topics encompass physics for organic transistors, structure control technologies of polymer semiconductors, nanomaterials electronics, organic solar cells, organic electroluminescence and dynamics for excitation, among others. In this second edition, the topics that have had particular progress in the field of organic electronics over the past seven years were added. For example, Thermally Activated Delayed Fluorescence (TADF) technology for organic LED, the development of perovskite materials, light-emitting materials using nanomaterials and the development of skin sensors and wearable/embedded devices. The recent scientific understanding of organic electronics is also introduced. This book will help readers to be able to contribute to society with the technologies and science of organic electronics materials in the future. .
Optical materials. --- Chemistry, Organic. --- Semiconductors. --- Nanotechnology. --- Polymers. --- Optical Materials. --- Organic Chemistry. --- Materials science.
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This book deals with neurotrophins (NGF, BDNF, NT3, NT4), which can decrease cell death, induce differentiation, as well as sustain the structure and function of neurons. This makes neurotrophins potential therapeutic agents for the treatment of neurodegenerative disorders. However, these proteins have so far been ineffective in clinical trials mostly because they cannot pass the blood-brain barrier owing to their high-molecular weights. Consequently, small molecules that mimic neurotrophins and stimulate the synthesis of endogenous neurotrophins or enhance their neurotrophic actions are expected to be promising alternatives. Small-molecule natural products, which have been used in dietary functional foods or in traditional medicine over the course of human history, have potential to be developed as new therapeutic agents against neurodegenerative conditions such as Alzheimer’s disease. In this book, the authors introduce a variety of natural products possessing neurotrophic properties such as neurogenesis, neurite outgrowth promotion (neuritogenesis), and neuroprotection and focus on the chemistry and biology of several neurotrophic natural products.
Natural products. --- Chemistry. --- Neurochemistry. --- Chemistry, Organic. --- Natural Products. --- Chemical Synthesis. --- Organic Chemistry.
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This open access volume compiles student reports from the 2023 Simula Summer School in Computational Physiology. The reports provide an overview of some tools available to model physiology in excitable tissues across scales and scientific questions. In 2023, Simula held the nineth annual Summer School in Computational Physiology in collaboration with the University of Oslo (UiO) and the University of California, San Diego (UCSD). Each year, the course focuses on modeling excitable tissues, with a special interest in cardiac physiology and neuroscience. Group research projects conducted by graduate students from around the world result in reports addressing problems of physiological importance. Reports may not necessarily represent new scientific results; rather, they can reproduce or supplement earlier studies. Reports from seven of the summer projects are included as separate chapters. The topics represented include multiscale mechanics, electrophysiology, pharmacology, and machine learning. This is an open access book.
Mathematics --- Neurosciences. --- Pharmacology. --- Chemistry, Organic. --- Computational Mathematics and Numerical Analysis. --- Neuroscience. --- Organic Chemistry. --- Data processing.
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