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Histology. Cytology

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This book provides an overview of some of the latest developments in the medical sciences, with particular emphasis on the experimental and theoretical aspects of modern medicine. In recent years, researchers working in applied health sciences have been able to identify diseases indicated by chemokines. Among the topics discussed in this book are chemokines affecting platelet functions, cytokine levels, and oxidative stress parameters in COVID-19, chemokines at the intersection of diabetes-tuberculosis synergy, chemokines in periodontal diseases, pathogenic links between hepato-digestive disorders and periodontal conditions, and IL-inflammatory carcinogenesis. Other areas included are the role of 23 receptor gene variations, the relationship between interleukin-5 Receptor polymorphism, and immunological parameters in children with asthma. The book's primary target audience includes students, researchers, medical practitioners, dentists, pharmacologists, and professionals interested in related fields. The book has been written by expert international scientists active in research in the health and applied sciences. We hope it will increase scientists' knowledge of the complexity of some medical approaches, and encourage both professionals and students to devote part of their future research to understanding the mechanisms and applications of chemokines.

Cellular biology (cytology) --- Chemokines.

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This detailed volume provides methods to guide assay development, procedures designed to investigate the chemokine and glycosaminoglycan (GAG) networks, as well as their interactions, in a wide range of organs and tissues in disease and in health. The initial chapters in this book present in vivo models used to examine the roles of chemokines and GAGs in normal physiology and in the pathophysiology of disease. The book then explores present cell- and tissue-based in vitro assays to examine chemokine:GAG interactions. Finally, analytic approaches are presented that provide assays for measuring GAGs, chemokines, and cellular responses. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Chemokine-Glycosaminoglycan Interactions: Methods and Protocols serves as an ideal guide for researchers seeking to analyze chemokine and GAG functions, interactions, and molecular mechanisms in vivo and in vitro.

Immunology. --- Cytology. --- Cell Biology.

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Comprendre l'origine et le fonctionnement des cellules, c'est comprendre à quoi tient la vie sur Terre. Un voyage fascinant dans le temps et l'infiniment petit ! Tout ce qui vit sur Terre (animaux, plantes, algues, champignons) est constitué de cellules ayant toutes pour origine une même cellule ancestrale commune : LUCA (Last Universal Common Ancestor). Comprendre comment cette première cellule est apparue il y a des milliards d'années, puis a évolué pour former tous les organismes actuels est une plongée au coeur même du vivant. Passionné de cellules, d'embryons et de plancton, auxquels il a consacré sa vie de chercheur et d'artiste, Christian Sardet, de la façon la plus simple et la plus imagée possible, nous raconte comment fonctionnent et communiquent les cellules, et ce que nous en savons aujourd'hui. Ce livre contient 200 illustrations et dessins originaux.

Cytology. --- Cells. --- Biologie cellulaire.

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This book provides a unique, comprehensive, and up-to-date overview of the various NADPH oxidases and narrates the history of their discovery, biochemical characteristics, genetics, molecular structure, and multiple functions in health and disease. It covers the subject in a manner that serves both the expert and the novice researcher in the field. The book starts with an overview of the major milestones in the discovery of the archetypical NADPH oxidase, known as cytochrome b558, and its cytosolic regulators. This is followed by personal recollections by pioneers of the field, descriptions of the work of the major figures of the past by their followers, and a rendering of the history of the discovery of the Nox family. The central section of the book consists of chapters devoted specifically to an in depth description of the individual members of the Nox family, and is followed by chapters focused on the modulators of their function. A subsequent section comprises chapters dealing with methodologies of Nox research, interaction with other proteins, and Nox inhibitors. A distinct section of the book deals with non-mammalian Noxs, from amoeba to zebrafish. Subsequent chapters focus on Nox structure, a field in which extraordinary progress was made in recent years. The volume ends with chapters on Chronic Granulomatous Disease, the consequence of Nox loss-of-function, and its treatment by gene therapy. The coda is a crystal ball perspective of the hopes for the clinical translation of basic Nox research. Written for biochemists, cell biologists, molecular biologists, and clinicians, this book is aimed at both senior scientists and young investigators in the field.

Chemistry --- Histology. Cytology --- cytologie --- proteïnen