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Forkhead Transcription Factors. --- Wnt Signaling Pathway. --- Neoplasms.

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Written by expert contributors, this much-needed book emphasizes a quantitative and comprehensive perspective to explore the many dimensions of cellular Ca2+ signalling. Leading researchers in the field of calcium signaling present key aspects of this process in cells, starting with Ca2+ entry into the cell, its uptake from the cytosol by organelles, such as the endoplasmic reticulum and mitochondria, and the actions of Ca2+ in turn on a variety of important cellular regulatory processes. This research and reference text should prove useful to a wide readership, from students to researchers at many different levels, particularly in physiology, pharmacology, or biomedical engineering. Part of Biophysical Society-IOP series.

SCIENCE / Life Sciences / Biophysics. --- Calcium --- Cellular signal transduction. --- Calcium Signaling. --- Signal Transduction. --- Biophysics. --- Physiological effect.

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A natural history of cheating from selfish genes to lying politiciansNature is rife with cheating. Possums play possum, feigning death to cheat predators. Crows cry wolf to scare off rivals. Amphibians and reptiles are inveterate impostors. Even genes and cells cheat. The Liars of Nature and the Nature of Liars explores the evolution of cheating in the natural world, revealing how dishonesty has given rise to wondrous diversity.Blending cutting-edge science with a wealth of illuminating examples—from microscopic organisms to highly intelligent birds and mammals—Lixing Sun shows how cheating in nature relies on two basic rules. One is lying, by which cheaters exploit honest messages in communication signals and use them to serve their own interests. The other is deceiving, by which cheaters exploit the biases and loopholes in the sensory systems of other creatures. Sun demonstrates that cheating serves as a potent catalyst in the evolutionary arms race between the cheating and the cheated, resulting in a biological world teeming with complexity and beauty.Brimming with insight and humor, The Liars of Nature and the Nature of Liars also looks at the prevalence of cheating in human society, identifying the kinds of cheating that spur innovation and cultural vitality and laying down a blueprint for combatting malicious cheating such as fake news and disinformation.

Adaptation (Biology) --- Environmental adaptation --- Adaptation, Environmental --- Biology --- Self-organizing systems --- Variation (Biology) --- Biological fitness --- Genetics --- Alternative reproductive tactics. --- Arms race. --- Camouflage. --- Cheating. --- Communication. --- Deception. --- Delusion. --- Disinformation. --- Evolution. --- Free riding. --- Honest signaling. --- Illusion. --- Infidelity. --- Lying. --- Mimicry. --- Natural selection. --- Nest/brood parasitism. --- Placebo effect. --- Self-deception. --- Sexual selection. --- Chicanery --- Deceit --- Subterfuge --- Truthfulness and falsehood --- Intrigue

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Pharmacological and molecular cloning studies have shown that the superfamily of G-protein coupled receptors (GPCRs) forms one of the largest and most diverse protein families in nature. The aim of this book is to bring together all aspects of GPCR structure and function.

GTP-Binding Protein Regulators --- Receptors, Cell Surface --- GTP-Binding Proteins --- Central Nervous System Diseases --- Nervous System Diseases --- Carrier Proteins --- Intracellular Signaling Peptides and Proteins --- GTP Phosphohydrolases --- Proteins --- Membrane Proteins --- Acid Anhydride Hydrolases --- Amino Acids, Peptides, and Proteins --- Peptides --- Diseases --- Hydrolases --- Enzymes --- Enzymes and Coenzymes --- G proteins --- Cell receptors. --- Receptors.

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This book covers the recently developed understanding of Electro-Mechano-Biology (EMB) in which the focus is primarily on the couplings between the electric and mechanical fields. The emphasis lies on the analytical and computational aspects of EMB at the cellular level. The book is divided into two parts. In the first part, the author starts by defining and discussing the relevant basic aspects of the electrical and mechanical properties of cell membranes. He provides an overview of some of the ways analytical modelling of cell membrane electrodeformation (ED) and electroporation (EP) appears in a variety of contexts as well as a contemporary account of recent developments in computational approaches that can feature in the theory initiative, particularly in its attempt to describe the cohort of activities currently underway. Intended to serve as an introductory text and aiming to facilitate the understanding of the field to non-experts, this part does not dwell on the set of topics, such as cellular mechanosensing and mechanotransduction, irreversible EP, and atomistic molecular dynamics modelling of membrane EP. The second (and larger) part of the book is devoted to a presentation of the necessary analytical and computational tools to illustrate the ideas behind EMB and illuminate physical insights. Brief notes on the history of EMB and its many applications describing the variety of ideas and approaches are also included. In this part, the background of the first principles and practical calculation methods are discussed to highlight aspects that cannot be found in a single volume.

Biomechanics. --- Electrophysiology. --- Animal electricity --- Bioelectricity --- Electricity, Animal --- Electrobiology --- Neurology --- Physiology --- Electricity --- Biological mechanics --- Mechanical properties of biological structures --- Biophysics --- Mechanics --- Contractility (Biology) --- Physiological effect --- Biophysics. --- Cell interaction. --- Mathematical physics. --- Computer simulation. --- Mechanobiological Cell Signaling. --- Computational Physics and Simulations. --- Computer modeling --- Computer models --- Modeling, Computer --- Models, Computer --- Simulation, Computer --- Electromechanical analogies --- Mathematical models --- Simulation methods --- Model-integrated computing --- Physical mathematics --- Physics --- Mathematics --- Cell-cell interaction --- Cell communication --- Cellular communication (Biology) --- Cellular interaction --- Intercellular communication --- Cellular control mechanisms --- Biological physics --- Biology --- Medical sciences