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Antimicrobial resistance remains a major concern in medicine, especially during the COVID-19 pandemic, where microbial infections were frequent complications. To combat drug-resistant pathogens, there has been a renewed interest in the use of antimicrobial peptides (AMPs). This reprint focuses on the in-silico approaches used for the rational discovery and design of AMPs. Such computational methodologies range from classical homology-based and machine-learning prediction algorithms to complex similarity networks and evolutionary algorithms that use models of sequence evolution. Furthermore, the reprint explores the improvement of high-throughput screening techniques in the discovery of AMPs from biological samples, which has also led to the evolution of computational approaches that aid in this biodiscovery process. The reprint contains original research and review papers, which serve as valuable references for researchers dedicated to peptide drug development.

Microbial peptides.

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Drug development. --- Development of drugs --- Drugs --- New drug development --- Pharmacology --- Pharmacy --- Development --- Peptide antibiotics. --- Drug resistance. --- Antimicrobial Peptides --- Drug Resistance

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Peptides --- Nanobiotechnology. --- Drugs --- Drug design --- Pharmaceutical design --- Drug development --- Bionanotechnology --- Biotechnology --- Nanotechnology --- Biotechnology. --- Design. --- Nanobiotechnology --- Nanostructured materials --- Drug Design --- Therapeutic use.

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Viruses have properties that are distinct from other living organisms and so require different methods to culture them. This volume provides a broad treatment of the principles and practice of virus culture.

Plant Viruses --- Antibodies, Monoclonal --- Virus Cultivation --- Antiviral Agents --- Microscopy, Electron --- Viral Vaccines --- Virology --- Viruses --- Antibodies --- Microbiological Techniques --- Microscopy --- Microbiology --- Anti-Infective Agents --- Vaccines --- Immunoglobulins --- Biological Products --- Biology --- Therapeutic Uses --- Diagnostic Imaging --- Investigative Techniques --- Organisms --- Clinical Laboratory Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Serum Globulins --- Complex Mixtures --- Immunoproteins --- Biological Science Disciplines --- Diagnostic Techniques and Procedures --- Pharmacologic Actions --- Globulins --- Blood Proteins --- Diagnosis --- Chemicals and Drugs --- Natural Science Disciplines --- Chemical Actions and Uses --- Proteins --- Disciplines and Occupations --- Amino Acids, Peptides, and Proteins --- Microbiology & Immunology --- Health & Biological Sciences --- Gene Products, Protein --- Gene Proteins --- Protein --- Protein Gene Products --- Proteins, Gene --- Molecular Mechanisms of Pharmacological Action --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Antemortem Diagnosis --- Diagnoses and Examinations --- Examinations and Diagnoses --- Postmortem Diagnosis --- Diagnose --- Antemortem Diagnoses --- Diagnoses --- Diagnoses, Antemortem --- Diagnoses, Postmortem --- Diagnosis, Antemortem --- Diagnosis, Postmortem --- Postmortem Diagnoses --- Disease --- Blood Protein --- Plasma Protein --- Plasma Proteins --- Serum Protein --- Serum Proteins --- Protein, Blood --- Protein, Plasma --- Protein, Serum --- Proteins, Blood --- Proteins, Plasma --- Proteins, Serum --- Globulin --- Chemical Actions --- Actions, Chemical --- Actions, Pharmacologic --- Pharmacological and Toxicological Phenomena --- Drug Therapy --- Diagnostic Technics and Procedures --- Technics and Procedures, Diagnostic --- Techniques and Procedures, Diagnostic --- Diagnostic Testing --- Testing, Diagnostic --- Sensitivity and Specificity --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Complex Extracts --- Crude Extracts --- Extracts, Complex --- Extracts, Crude --- Complex Extract --- Complex Mixture --- Crude Extract --- Mixtures, Complex --- Extract, Complex --- Extract, Crude --- Mixture, Complex --- Euglobulins --- Pseudoglobulins --- Globulins, Serum --- Clinical Laboratory Diagnoses --- Clinical Laboratory Testings --- Clinical Laboratory Tests --- Diagnoses and Laboratory Examinations --- Diagnosis, Laboratory --- Laboratory Diagnosis --- Laboratory Examinations and Diagnoses --- Laboratory Techniques, Clinical --- Clinical Laboratory Technique --- Clinical Laboratory Test --- Clinical Laboratory Testing --- Diagnose, Clinical Laboratory --- Laboratory Diagnoses --- Laboratory Technique, Clinical --- Laboratory Test, Clinical --- Laboratory Testing, Clinical --- Technique, Clinical Laboratory --- Test, Clinical Laboratory --- Testing, Clinical Laboratory --- Laboratories --- Medical Laboratory Science --- Clinical Laboratory Services --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Imaging, Diagnostic --- Imaging, Medical --- Medical Imaging --- Radiologic and Imaging Nursing --- Image Processing, Computer-Assisted --- Therapeutic Effects --- Therapeutic Effect --- Therapeutic Use --- Effect, Therapeutic --- Effects, Therapeutic --- Use, Therapeutic --- Uses, Therapeutic --- Biologic Drugs --- Biologic Medicines --- Biologic Pharmaceuticals --- Biologic Products --- Biological Drugs --- Biological Medicines --- Biologicals --- Biopharmaceuticals --- Products, Biological --- Biologic --- Biologic Drug --- Biologic Product --- Biological --- Biological Drug --- Biological Medicine --- Biological Product --- Biologics --- Biopharmaceutical --- Natural Product --- Natural Products --- Drug, Biologic --- Drug, Biological --- Drugs, Biologic --- Drugs, Biological --- Medicine, Biological --- Medicines, Biologic --- Medicines, Biological --- Pharmaceuticals, Biologic --- Product, Biologic --- Product, Biological --- Product, Natural --- Biological Factors --- Immunoglobulin --- Globulins, Immune --- Immune Globulin --- Immune Globulins --- Globulin, Immune --- Genes, Immunoglobulin --- Vaccine --- Anti-Microbial Agents --- Antiinfective Agents --- Antimicrobial Agents --- Anti-Infective Agent --- Anti-Microbial Agent --- Antimicrobial Agent --- Microbicide --- Microbicides --- Agent, Anti-Infective --- Agent, Anti-Microbial --- Agent, Antimicrobial --- Agents, Anti-Infective --- Agents, Anti-Microbial --- Agents, Antiinfective --- Agents, Antimicrobial --- Anti Infective Agent --- Anti Infective Agents --- Anti Microbial Agent --- Anti Microbial Agents --- Infections --- Parasites --- Infectious Disease Medicine --- Compound Microscopy --- Hand-Held Microscopy --- Light Microscopy --- Optical Microscopy --- Simple Microscopy --- Hand Held Microscopy --- Microscopy, Compound --- Microscopy, Hand-Held --- Microscopy, Light --- Microscopy, Optical --- Microscopy, Simple --- Microbiologic Technic --- Microbiologic Technics --- Microbiologic Technique --- Microbiological Technics --- Technic, Microbiologic --- Technics, Microbiological --- Technique, Microbiologic --- Techniques, Microbiologic --- Microbiologic Techniques --- Microbiological Technic --- Microbiological Technique --- Technic, Microbiological --- Technics, Microbiologic --- Technique, Microbiological --- Techniques, Microbiological --- Animal Viruses --- Zoophaginae --- Animal Virus --- Virus --- Virus, Animal --- Viruses, Animal --- Genetic Vectors --- Viral Vaccine --- Vaccine, Viral --- Vaccines, Viral --- Electron Microscopy --- Antiviral Drugs --- Antiviral --- Antiviral Agent --- Antiviral Drug --- Antivirals --- Agent, Antiviral --- Agents, Antiviral --- Drug, Antiviral --- Drugs, Antiviral --- Interferon Inducers --- Virus Diseases --- Virus Inactivation --- Viral Cultivation --- Cultivation, Viral --- Cultivation, Virus --- Cultivations, Viral --- Cultivations, Virus --- Viral Cultivations --- Virus Cultivations --- Culture Techniques --- Monoclonal Antibodies --- Monoclonal Antibody --- Antibody, Monoclonal --- Hybridomas --- Phytophagineae --- Plant Virus --- Virus, Plant --- Viruses, Plant --- diagnosis --- blood --- methods --- Virus Cultivation. --- Virologie --- Cultures and culture media --- Cultures et milieux de culture --- Organelles --- Occupations --- Cultures and culture media.