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If the NHS and its healthcare companies have only recently become aware of being faced with a "new normality", and, therefore, of having to "shed their skin" to face the challenges connected to it, a new normality for Life Science companies, perhaps best described as a perfect storm, it has become a reality at least since the early years of the new century. The world in which access to the market, the introduction of innovation, and consolidation of sales were built around the supervision of regulatory processes and the share of voice towards the prescribers have become much more complex. A context that many define as VUCA (volatile, uncertain, complex, ambiguous). In this book, therefore, both the reasons that prompted Life Science companies to rethink their strategy by dedicating increasing attention to the political and institutional decision-makers of the Regions and the management of healthcare companies, and the internal organization to support and strengthen their "market access" capabilities. Through the different perspectives - academic, consultancy, managerial - of the three authors, the logic that has guided the "change of skin" of Life Science companies is explored, as the functional tools for market access, the different declinations that this activity has had in the sector, future scenarios and further evolutionary prospects, the connection with the other company functions - sales, marketing, medical management, institutional affairs, administration - and many technical aspects which are the heart of the skills and toolbox required of those who want to successfully develop a career right in the field of market access.

Life sciences. --- Management.

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Humans have eaten nuts for thousands of years, yet their consumption was discouraged just a few decades ago due to their high-fat content. This perspective began to change in the early 1990s due to seminal publications from the Adventist Health Study, which showed that nut consumption significantly improved heart health-related outcomes. Many randomized clinical trials, epidemiological studies, and in vitro/in vivo mechanistic studies have since explored the role of eating nuts and its relation to health. Similarly, dried fruits have been scrutinized due to their concentrated sugar content despite their non-sodium micronutrient and fiber density. Due to accumulating evidence on nut and dried fruit intake and health outcomes, an international scientific meeting was organized for leading experts to examine and recapitulate in detail what is well known and established and what avenues of knowledge are still lacking in nut and dried fruit research. This book summarizes proceedings from this international scientific meeting and the latest information relating to: (1) energy balance and body weight; (2) insulin resistance and diabetes; (3) lipoproteins and dyslipidemia; (4) gastrointestinal system; (5) inflammation and oxidation; (6) cardiovascular disease; (7) cognition; (8) cancer; (9) dried fruit and health; (10) future lines of research. These findings highlight the beneficial health potentials of nuts for researchers, health professionals, other stakeholders, and the public while simultaneously pinpointing areas for further investigation to continue informing and guiding health practices and policies.

Life sciences. --- Life (Biology)

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If the NHS and its healthcare companies have only recently become aware of being faced with a "new normality", and, therefore, of having to "shed their skin" to face the challenges connected to it, a new normality for Life Science companies, perhaps best described as a perfect storm, it has become a reality at least since the early years of the new century. The world in which access to the market, the introduction of innovation, and consolidation of sales were built around the supervision of regulatory processes and the share of voice towards the prescribers have become much more complex. A context that many define as VUCA (volatile, uncertain, complex, ambiguous). In this book, therefore, both the reasons that prompted Life Science companies to rethink their strategy by dedicating increasing attention to the political and institutional decision-makers of the Regions and the management of healthcare companies, and the internal organization to support and strengthen their "market access" capabilities. Through the different perspectives - academic, consultancy, managerial - of the three authors, the logic that has guided the "change of skin" of Life Science companies is explored, as the functional tools for market access, the different declinations that this activity has had in the sector, future scenarios and further evolutionary prospects, the connection with the other company functions - sales, marketing, medical management, institutional affairs, administration - and many technical aspects which are the heart of the skills and toolbox required of those who want to successfully develop a career right in the field of market access.

Life sciences. --- Management.

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La Biotecnología Ambiental emplea el uso de organismos para la prevención, monitoreo y remediación de los ecosistemas, al mismo tiempo permite la generación de bioproductos y energía limpia. El libro consistió en tres capítulos, en el primero se establece los fundamentos de la Biotecnología Ambiental y sus aplicaciones en entornos terrestre, acuático y aéreo; además, se presentan herramientas aplicadas como los biosensores en el monitoreo ambiental, la fitorremediación en varios contextos de América Latina y el fortalecimiento de la agricultura sustentable. En el segundo capítulo se describe la importancia de un estudio bibliométrico y el enfoque para las diversas investigaciones, se detalla un manual de uso, que permite su replicabilidad en otros contextos. Además de presentar un caso de estudio aplicado al tema central de este libro, que sistematiza los temas más estudiados, las tendencias, revistas y países con mayores contribuciones. En el tercer capítulo se presentan varias prácticas de laboratorio y una sección de preguntas, que pueden ser empleadas en otras instituciones educativas o de manera autónoma. En conclusión, los capítulos son complementarios entre sí, facilitando la comprensión e interés del lector. El área de mayor relevancia corresponde a la biorremediación en suelos contaminados por hidrocarburos y metales pesados, los grupos más frecuentes en la revisión fueron hongos, cianobacterias y organismos genéticamente modificados. Finalmente, existe una oportunidad del uso y la potencial combinación de las técnicas basadas en metagenómica, ADN ambiental, inteligencia artificial para el desarrollo de las nuevas tendencias de la Biotecnología Ambienta.

Biosphere. --- Life sciences.

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Humans have eaten nuts for thousands of years, yet their consumption was discouraged just a few decades ago due to their high-fat content. This perspective began to change in the early 1990s due to seminal publications from the Adventist Health Study, which showed that nut consumption significantly improved heart health-related outcomes. Many randomized clinical trials, epidemiological studies, and in vitro/in vivo mechanistic studies have since explored the role of eating nuts and its relation to health. Similarly, dried fruits have been scrutinized due to their concentrated sugar content despite their non-sodium micronutrient and fiber density. Due to accumulating evidence on nut and dried fruit intake and health outcomes, an international scientific meeting was organized for leading experts to examine and recapitulate in detail what is well known and established and what avenues of knowledge are still lacking in nut and dried fruit research. This book summarizes proceedings from this international scientific meeting and the latest information relating to: (1) energy balance and body weight; (2) insulin resistance and diabetes; (3) lipoproteins and dyslipidemia; (4) gastrointestinal system; (5) inflammation and oxidation; (6) cardiovascular disease; (7) cognition; (8) cancer; (9) dried fruit and health; (10) future lines of research. These findings highlight the beneficial health potentials of nuts for researchers, health professionals, other stakeholders, and the public while simultaneously pinpointing areas for further investigation to continue informing and guiding health practices and policies.

Life sciences. --- Life (Biology)