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Multifaceted Role of IL-1 in Cancer and Inflammation summarizes the existing literature and discusses future perspectives about the role of IL-1 in immune suppression, cancer progression, angiogenesis, and resistance to immunotherapies. The book presents mechanisms to overcome IL-1 mediated immune suppression in tumor microenvironment and covers topics on the source of IL-1 in the tumor microenvironment, IL-1 mediated downstream pathway, mechanism of IL-1 mediated immune suppression in cancer, and its effect on immunotherapy of cancer. Those topics help readers understand the effect of IL-1 on cancer immunopathology and immunotherapy, and provide them with broader concepts to develop therapies for IL-1 enrichment tumors.

Cancer --- Immunological aspects. --- Carcinogenesis --- Immunological aspects --- Interleukin-1 --- Neoplasms --- Immunotherapy --- Tumor Microenvironment --- Immunology. --- immunology --- Interleukin-1. --- Immunotherapy. --- Tumor Microenvironment. --- immunology.