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This book describes the emergence and recent advances in the design and development of rhodium complexes as therapeutic agents. Different classes of anticancer rhodium complexes with particular emphasis on ligands containing nitrogen-oxygen donor atoms are presented. Anticancer rhodium complexes of N-heterocyclic carbenes are described, while half-sandwich, heterobimetallic, and multinuclear rhodium complexes are discussed. Therapeutic applications of rhodium complexes beyond cancer such as antibacterial agents or antiviral agents are also analyzed, among others. Their mechanism of action is overviewed in detail, and the authors thoroughly comment on the challenges and future outlooks of research in the development of rhodium metallodrugs. This title highlights the important research carried out in the development of therapeutic rhodium complexes and is of great interest to graduates and researchers working in the area of rhodium-based therapeutic drugs.
Bioinorganic chemistry. --- Coordination compounds. --- Medicinal chemistry. --- Microclusters. --- Bioinorganic Chemistry. --- Coordination Chemistry. --- Medicinal Chemistry. --- Atomic and Molecular Clusters. --- Atomic clusters --- Clusters, Atomic --- Clusters, Molecular --- Microcluster physics --- Molecular clusters --- Atoms --- Microphysics --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Chemistry, Physical and theoretical --- Complex compounds --- Sequestration (Chemistry) --- Bio-inorganic chemistry --- Biological inorganic chemistry --- Inorganic biochemistry --- Biochemistry --- Chemistry, Inorganic --- Cancer --- Rhodium compounds --- Chemotherapy. --- Therapeutic use.
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