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Dosage forms are pharmaceutical formulation products in the form in which they are presented in the market. They are a crucial component of contemporary pharmaceutical research. The field of dosage forms is large and diverse and includes everything from conventional solid and liquid dosage forms to more recent innovations like nanoparticles and gene therapy. This book provides a comprehensive overview of dosage forms, including their formulation and development. Chapters address such topics as novel dosage forms in ophthalmic applications, orally disintegrating tablets, layered tablets, pharmacokinetics and pharmacogenomics, and much more.
Pharmacology. --- Drugs --- Dosage forms.
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Model-informed precision dosing (MIPD) is an advanced quantitative approach focusing on individualized treatment optimization. MIPD integrates mathematical models of drugs and diseases combined with individual patient characteristics (e.g., genotype, anthropometric factors, and organ function). MIPD has been highlighted as a useful tool for drug dosage selection in both the drug development process and clinical practice and it is a rapidly growing discipline that is supported by the main drug regulatory agencies. Despite the potential benefits of this methodology toward personalized medicine, its application is still limited. The Special Issue presented here includes several PKPD and PBPK models focused on improving the current state of art regarding the PK behaviour of different drugs with the aim of improving the efficacy/safety balance of these treatments and their clinical outcome; the Special Issue is intended to be of particular interest for clinical pharmacologists, pharmacometricians, and specific clinicians who routinely use the considered drugs.
Drugs --- Dosage. --- Dosage of drugs --- Dosiology --- Microdosage of drugs --- Posology --- Microdosage --- Administration
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Molecular Targeted Therapy --- Neoplasms --- Antineoplastic Agents --- Antineoplastic Agents, Immunological --- methods --- drug therapy --- administration & dosage --- metabolism --- Cancer --- Drug targeting. --- Chemotherapy.
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"Tailor-Made Polysaccharides in Drug Delivery provides extensive details on all the vital precepts, basics and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industry for understanding and developing high quality products. The book offers a comprehensive resource to understand the potential of the materials in forming new drug delivery methods."--
Polysaccharides. --- Drug Carriers. --- Drug Delivery Systems. --- Drug Targeting --- Delivery System, Drug --- Delivery Systems, Drug --- Drug Delivery System --- Drug Targetings --- System, Drug Delivery --- Systems, Drug Delivery --- Targeting, Drug --- Targetings, Drug --- Dosage Forms --- Drug Carrier --- Magnetic Iron Oxide Nanoparticles --- Drug Delivery Systems --- Glycan --- Glycans --- Polysaccharide --- Biopolymers --- Drug delivery systems. --- Polysaccharides --- Biotechnology. --- Delivery systems, Drug --- Drug administration technology --- Drug delivery technology --- Drugs --- Pharmaceutical technology --- Delivery systems
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"Smart Nanomaterials for Bioencapsulation focuses on the fundamentals, synthesis methods and matrix design for the encapsulation of drugs, drug release, food and nutraceuticals, mechanisms of nano- encapsulated drugs on liposomes, micelles, silica composites, carbon nanotubes, dendrimers, and protein inorganic nanohybrids. Providing detailed information on the encapsulation of food and drug derivatives, the book helps create new and modern approaches for both pharmaceutical and nutritional science. The target delivery of pharmacological agents, as well as food additives under various conditions is covered, including sections on systemic release of drug molecules, minimum loss at non-target sites, the accumulation of diseased tissue or organs, and more."--
Drugs --- Nanostructured materials. --- Coatings. --- Nanomaterials --- Nanometer materials --- Nanophase materials --- Nanostructure controlled materials --- Nanostructure materials --- Ultra-fine microstructure materials --- Microstructure --- Nanotechnology --- Drug coatings --- Coatings --- Pharmaceutical technology --- Enteric-coated tablets --- Dosage forms --- Drug carriers (Pharmacy) --- Capsules --- Nanoparticle Drug Delivery System --- Drug Carriers --- Nanostructures
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Animals, Exotic. --- Fishes. --- Amphibians --- Birds --- Hedgehogs. --- Rodentia --- Rabbits --- Ferrets --- Swine, Miniature. --- Primates --- Veterinary Drugs --- Drug Therapy --- Animaux exotiques --- Nouveaux animaux de compagnie --- Médicaments vétérinaires. --- veterinary --- Maladies. --- Animals, Exotic --- Fishes --- Hedgehogs --- Swine, Miniature --- Amphibians. --- Birds. --- Rodentia. --- Rabbits. --- Ferrets. --- Primates. --- Veterinary Drugs. --- veterinary. --- Exotic animals. --- Veterinary drugs --- Veterinary drugs. --- Dosage.
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Three-volumes book “Handbook of II-VI Semiconductor-Based Sensors and Radiation Detectors” is the first to cover both chemical sensors and biosensors and all types of photodetectors and radiation detectors based on II-VI semiconductors. It contains a comprehensive and detailed analysis of all aspects of the application of II-VI semiconductors in these devices. The first volume "Materials and Technologies" of a three-volume set describes the physical, chemical and electronic properties of II-VI compounds, which give rise to an increased interest in these semiconductors. Technologies that are used in the development of various devices based on II-VI connections, such as material synthesis, deposition, characterization, processing, and device fabrication, are also discussed in detail in this volume. It covers also topics related to synthesis and application of II-VI-based nanoparticles and quantum dots, as well their toxicity, biocompatibility and biofunctionalization. Consider of both chemical and biosensors and all types of radiation detectors based on II-VI semiconductors; Feature detailed analysis of all aspects of II-VI semiconductors; Maximize reader understanding of the present status of II-VI semiconductors and their role in the development of new generation of sensors and radiation detectors; Stands as an ideal reference for researchers concerned with electronics, optoelectronics, chemical and bio sensors, electrical engineering, biomedical applications and a robust supplement for university students and faculty.
Semiconductors. --- Chemical detectors. --- Radiation dosimetry. --- Materials. --- Detectors. --- Sensors. --- Radiation Dosimetry and Protection . --- Sensors and biosensors. --- Materials for Devices. --- Sensors --- Engineering instruments --- Physical instruments --- Engineering --- Engineering materials --- Industrial materials --- Engineering design --- Manufacturing processes --- Dosimetry --- Radiation --- Radiation monitoring --- Nuclear counters --- Chemical sensors --- Chemical apparatus --- Detectors --- Crystalline semiconductors --- Semi-conductors --- Semiconducting materials --- Semiconductor devices --- Crystals --- Electrical engineering --- Electronics --- Solid state electronics --- Materials --- Dosage --- Measurement --- Semiconductors Materials.
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This open access book describes modern applications of computational human modelling to advance neurology, cancer treatment, and radio-frequency studies including regulatory, safety, and wireless communication fields. Readers working on any application that may expose human subjects to electromagnetic radiation will benefit from this book’s coverage of the latest models and techniques available to assess a given technology’s safety and efficacy in a timely and efficient manner. Describes computational human body phantom construction and application; Explains new practices in computational human body modeling for electromagnetic safety and exposure evaluations; Includes a survey of modern applications for which computational human phantoms are critical; This book describes modern applications of computational human modelling. This book is licensed under the terms of the Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0/ which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made. The images or other third party material in this book are included in the book's Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the book's Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
Biomedical engineering. --- Telecommunication. --- Radiation dosimetry. --- Biomedical Engineering and Bioengineering. --- Microwaves, RF Engineering and Optical Communications. --- Radiation Dosimetry and Protection . --- Dosimetry --- Radiation --- Radiation monitoring --- Nuclear counters --- Electric communication --- Mass communication --- Telecom --- Telecommunication industry --- Telecommunications --- Communication --- Information theory --- Telecommuting --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Dosage --- Measurement --- Electromagnetic Modeling for Electrical and Biological Systems --- Anatomical Models for Radiation Dosimetry --- Computational Human Phantoms --- Computational Human Models --- Electromagnetic safety and exposure evaluations
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The book covers all aspects of anesthesia in newborns, neonates (under 28 days) and premature babies. These patients are highly vulnerable, very small in size and weight, at very high risk, and have high mortality and morbidity, which gets further aggravated by the medical diseases and congenital abnormalities these babies may suffer from. The book provides knowledge that equips the anesthetists with the regional techniques used to provide both anesthesia and analgesia, including information about the drugs used, skills in providing neuraxial blocks, nerve blocks, etc., complications thereof and the specially designed equipment for these patients (IV cannula, endotracheal tubes, ryles tubes, laryngoscopes, SpO2 probes, monitors, incubators, warmers and heaters, mattresses, OT tables). The book covers the pharmacology of drugs used, the effect of anesthetic drugs on the developing brain, pulmonary physiology, airway assessment and management, ventilation modes, getting IV and arterial access, preoperative workup, anesthetic management, and postoperative care. It includes care and concerns from both surgical and anesthesia aspects. It covers all the common surgical diseases along with some rare cases such as oncological concerns, palliative care, ethical concerns and pain management. The book also discusses the role and use of ultrasound. The chapter on anesthesia for short procedures includes common birth and neonatal care injuries. The book contains chapters on fluid therapy, blood and blood product transfusion guidelines and indications, resuscitation of a newborn and neonate, and neonatal rehabilitation to improve neonatal outcomes. It contains a dedicated chapter on why these babies are at a high risk of morbidity and mortality and contributing maternal factors. All the chapters are written by experts in their fields with vast experience. This book bridges the gap in the knowledge of an anesthesiologist between anesthesia for children and adults and newborns, neonates and preterm babies.
Anesthesiology. --- Anaesthesiology --- Surgery --- Neonatal anesthesia. --- Anesthesia in obstetrics. --- Newborn infants --- Newborn infants. --- Premature infants. --- Anesthesia --- Anesthetics --- Infant, Newborn --- Infant, Premature --- Anesthesia, Obstetrical --- Hospital care. --- methods --- administration & dosage --- Hospital care --- Hospitals --- Anesthetics in obstetrics --- Obstetric anesthesia --- Obstetrics --- Neonatology --- Pediatric anesthesia --- Anesthesia, Gynecological --- Anesthesia, Obstetric --- Gynecologic Anesthesia --- Paracervical Block --- Anesthesia, Gynecologic --- Block, Paracervical --- Blocks, Paracervical --- Gynecological Anesthesia --- Obstetric Anesthesia --- Obstetrical Anesthesia --- Paracervical Blocks --- Neonatal Prematurity --- Premature Infants --- Preterm Infants --- Infant, Preterm --- Infants, Premature --- Infants, Preterm --- Premature Infant --- Prematurity, Neonatal --- Preterm Infant --- Gestational Age --- Obstetric Labor, Premature --- Premature Birth --- Newborns --- Neonate --- Infants, Newborn --- Neonates --- Newborn --- Newborn Infant --- Newborn Infants --- Birth, Premature --- Infants (Premature) --- Preemies --- Preterm infants --- Birth weight, Low --- Infants (Newborn) --- Newborns (Infants) --- Infants --- Nurseries
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