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This Special Issue, entitled “Advanced Polymer Nanocomposites”, collects high-level original and review papers, focused on scientific discussions and practical applications in the field of functional polymer nanocomposites, including (a) optoelectronic materials (papers 1–6), (b) biomedical materials (papers 7–12), and (c) other functional polymer nanocomposites (papers 13–18).

Technology: general issues --- POSS --- poly(vinyl chloride) --- plasticizer --- nanocomposites --- graphene --- electrically conductive adhesive --- fillers --- TiO2 --- Al2O3 --- BN --- resins --- wearable pressure sensor --- piezoresistive sensor --- fiber assembly --- nanofiber aerogel --- reduced graphene oxide --- nano-TiO2 --- poly-geminal dicationic ionic liquid --- hydroquinone --- catechol --- transparent polyimide --- nanocomposite --- film --- organoclay --- thermo-mechanical properties --- optical transparency --- CFRP --- Carbon nanotubes --- Nanocomposites --- Split Hopkinson Pressure Bar --- Energy absorption --- root canal obturation --- composites --- urethane acrylates --- nanoscale silicate platelets --- carbon dioxide-based resins --- dental resin composite --- montmorillonite --- palygorskite --- cartilage tissue --- amphiphilic gelatin microcapsules --- tissue-mimetic pellets --- magnetic stimulation --- CD44 receptor --- soluble polyimide --- polyurethane --- Jeffamine --- organic-inorganic hybrid film --- Stretchable transistor --- silicone nanoparticles --- PDMS --- TEOS --- hydrogels --- soft contact lenses --- polymerizable reduced graphene oxide --- in situ polymerization --- electrical conductivity --- dispersion of 2D nanosheets --- powder coating --- thermal conductivity --- heat dissipation --- thermal radiation --- vanadium redox flow battery --- carbon felt --- atmospheric plasma --- polyacrylonitrile --- 3D printing process --- mesoporous iron oxide --- microneedles --- minoxidil --- electrochemical polymerization --- PEDOT --- graphene oxide --- anti-fouling capability --- anti-bacterial capability --- black phosphorene --- boron nitride --- flame retardant --- waterborne polyurethane --- organic montmorillonite --- natural rubber --- damping properties --- mechanical properties