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In recent years, there has been rapid growth in the availability of innovative, non-combustible products, including oral tobacco-derived nicotine (OTDN) products, heated tobacco products (HTPs), and electronic cigarettes (also referred to as e-vapor products; EVPs). Industry, academic, and government researchers are developing and validating analytical methods to extract, separate, identify, and quantitate a variety of analytes from these innovative tobacco products using a wide range of analytical techniques. These analytes include constituents such as nicotine, degradants and impurities, flavors, non-tobacco ingredients, HPHCs, and other currently unknown constituents. In this Special Issue, we received nine contributions that covered the latest analytical methods that have been developed and applied for the chemical characterization or exposure assessment to tobacco product constituents of innovative non-combustible products. This Special Issue is representative of the importance of analytical sciences research in characterizing innovative non-combustible products for guiding product design, determining relative product performance, ensuring consistency during the manufacturing process, informing toxicological risk assessment, and enabling regulatory reporting. The current advances in the development and applications of the analytical methods reported in this Special Issue can be used to inform the harm reduction potential of innovative non-combustible products for adult smokers.
Research & information: general --- Chemistry --- Analytical chemistry --- on!® nicotine pouches --- nicotine --- dissolution --- release profile --- validation --- product assessment --- smokeless tobacco product --- nicotine degradants --- nicotine-related impurities --- alkaloids --- nicotine degradation products --- nicotine pouches --- reduced-risk products --- constituents --- method development --- method validation --- JUUL --- aerosol --- non-targeted analysis --- chemical characterization --- ENDS --- e-cigarette --- GC-MS --- LC-HRMS --- e-liquid --- 2,4-DNPH derivatization --- formaldehyde --- "hidden formaldehyde" --- formaldehyde-containing hemiacetal/acetal adducts --- HPHC --- GC-MS --- 3-hydroxybenzo[a]pyrene --- LC-MS/MS --- urine --- human biomonitoring --- derivatization --- potentially reduced-risk products --- propylene glycol --- electronic cigarette --- biomarker of exposure --- compliance marker --- oral tobacco derived nicotine (OTDN) pouches --- snus --- nicotine release --- nicotine dissolution --- nicotine extraction --- equivalence --- modern oral nicotine products --- HPHCs --- product characterizations --- on!® nicotine pouches --- nicotine --- dissolution --- release profile --- validation --- product assessment --- smokeless tobacco product --- nicotine degradants --- nicotine-related impurities --- alkaloids --- nicotine degradation products --- nicotine pouches --- reduced-risk products --- constituents --- method development --- method validation --- JUUL --- aerosol --- non-targeted analysis --- chemical characterization --- ENDS --- e-cigarette --- GC-MS --- LC-HRMS --- e-liquid --- 2,4-DNPH derivatization --- formaldehyde --- "hidden formaldehyde" --- formaldehyde-containing hemiacetal/acetal adducts --- HPHC --- GC-MS --- 3-hydroxybenzo[a]pyrene --- LC-MS/MS --- urine --- human biomonitoring --- derivatization --- potentially reduced-risk products --- propylene glycol --- electronic cigarette --- biomarker of exposure --- compliance marker --- oral tobacco derived nicotine (OTDN) pouches --- snus --- nicotine release --- nicotine dissolution --- nicotine extraction --- equivalence --- modern oral nicotine products --- HPHCs --- product characterizations
Choose an application
In recent years, there has been rapid growth in the availability of innovative, non-combustible products, including oral tobacco-derived nicotine (OTDN) products, heated tobacco products (HTPs), and electronic cigarettes (also referred to as e-vapor products; EVPs). Industry, academic, and government researchers are developing and validating analytical methods to extract, separate, identify, and quantitate a variety of analytes from these innovative tobacco products using a wide range of analytical techniques. These analytes include constituents such as nicotine, degradants and impurities, flavors, non-tobacco ingredients, HPHCs, and other currently unknown constituents. In this Special Issue, we received nine contributions that covered the latest analytical methods that have been developed and applied for the chemical characterization or exposure assessment to tobacco product constituents of innovative non-combustible products. This Special Issue is representative of the importance of analytical sciences research in characterizing innovative non-combustible products for guiding product design, determining relative product performance, ensuring consistency during the manufacturing process, informing toxicological risk assessment, and enabling regulatory reporting. The current advances in the development and applications of the analytical methods reported in this Special Issue can be used to inform the harm reduction potential of innovative non-combustible products for adult smokers.
Research & information: general --- Chemistry --- Analytical chemistry --- on!® nicotine pouches --- nicotine --- dissolution --- release profile --- validation --- product assessment --- smokeless tobacco product --- nicotine degradants --- nicotine-related impurities --- alkaloids --- nicotine degradation products --- nicotine pouches --- reduced-risk products --- constituents --- method development --- method validation --- JUUL --- aerosol --- non-targeted analysis --- chemical characterization --- ENDS --- e-cigarette --- GC–MS --- LC–HRMS --- e-liquid --- 2,4-DNPH derivatization --- formaldehyde --- “hidden formaldehyde” --- formaldehyde-containing hemiacetal/acetal adducts --- HPHC --- GC-MS --- 3-hydroxybenzo[a]pyrene --- LC–MS/MS --- urine --- human biomonitoring --- derivatization --- potentially reduced-risk products --- propylene glycol --- electronic cigarette --- biomarker of exposure --- compliance marker --- oral tobacco derived nicotine (OTDN) pouches --- snus --- nicotine release --- nicotine dissolution --- nicotine extraction --- equivalence --- modern oral nicotine products --- HPHCs --- product characterizations --- n/a --- LC-HRMS --- "hidden formaldehyde" --- LC-MS/MS
Choose an application
In recent years, there has been rapid growth in the availability of innovative, non-combustible products, including oral tobacco-derived nicotine (OTDN) products, heated tobacco products (HTPs), and electronic cigarettes (also referred to as e-vapor products; EVPs). Industry, academic, and government researchers are developing and validating analytical methods to extract, separate, identify, and quantitate a variety of analytes from these innovative tobacco products using a wide range of analytical techniques. These analytes include constituents such as nicotine, degradants and impurities, flavors, non-tobacco ingredients, HPHCs, and other currently unknown constituents. In this Special Issue, we received nine contributions that covered the latest analytical methods that have been developed and applied for the chemical characterization or exposure assessment to tobacco product constituents of innovative non-combustible products. This Special Issue is representative of the importance of analytical sciences research in characterizing innovative non-combustible products for guiding product design, determining relative product performance, ensuring consistency during the manufacturing process, informing toxicological risk assessment, and enabling regulatory reporting. The current advances in the development and applications of the analytical methods reported in this Special Issue can be used to inform the harm reduction potential of innovative non-combustible products for adult smokers.
on!® nicotine pouches --- nicotine --- dissolution --- release profile --- validation --- product assessment --- smokeless tobacco product --- nicotine degradants --- nicotine-related impurities --- alkaloids --- nicotine degradation products --- nicotine pouches --- reduced-risk products --- constituents --- method development --- method validation --- JUUL --- aerosol --- non-targeted analysis --- chemical characterization --- ENDS --- e-cigarette --- GC–MS --- LC–HRMS --- e-liquid --- 2,4-DNPH derivatization --- formaldehyde --- “hidden formaldehyde” --- formaldehyde-containing hemiacetal/acetal adducts --- HPHC --- GC-MS --- 3-hydroxybenzo[a]pyrene --- LC–MS/MS --- urine --- human biomonitoring --- derivatization --- potentially reduced-risk products --- propylene glycol --- electronic cigarette --- biomarker of exposure --- compliance marker --- oral tobacco derived nicotine (OTDN) pouches --- snus --- nicotine release --- nicotine dissolution --- nicotine extraction --- equivalence --- modern oral nicotine products --- HPHCs --- product characterizations --- n/a --- LC-HRMS --- "hidden formaldehyde" --- LC-MS/MS
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This book is a collection of a group of peer-reviewed scientific papers dealing with both the evaluation and the solution of the complex but pressing problem of water source pollution. In the case of both fresh and marine water, the environmental and health protection aspects are closely linked. Monitoring activities supply continuous information on the contamination levels in inland surface, ground, and coastal waters, providing an alert in case of increased or new contamination and monitoring the effectiveness of remediation strategies. On the other hand, new or improved remediation and bioremediation tools are urgently needed to tackle the scarcity of safe drinking water. The papers in this book represent interesting starting points for future researches.
Research & information: general --- Chemistry --- acute toxicity --- Daphnia magna --- electrochemical oxidation --- emerging contaminants --- methiocarb --- glucocorticoids --- TiO2-solar light degradation --- freshwater pollution --- photoproducts --- matrix constituents --- human health analysis --- water contamination --- water quality model --- hydraulic model --- WDS --- water quality sensors --- agrochemicals --- photo-reactor --- advanced oxidation processes --- water pollution --- point sources --- antioxidant enzymes --- pharmaceutical residues --- pesticides --- detergents --- integrative indexes --- groundwater pollution --- pollution costs --- economic environmental protection instruments --- physico-chemical parameters --- heavy metals --- health risk index --- Pearson coefficients --- adsorption --- dye --- MWCNT --- kinetics --- isotherm models --- thermodynamic --- bioaccumulation --- Lake Chapala --- carp --- catfish --- PTWI --- bioremediation --- ecotoxicology --- Gibbula umbilicalis --- marine bacteria --- tributyltin --- TBT-tolerance --- microalgae --- Vibrio fisheri --- benzenesulfonamide --- benzothiazole --- benzotriazole --- biotoxicity tests --- ferrous lactate --- in situ chemical reduction --- trichloroethylene (TCE) --- green and sustainable remediation (GSR) --- 1,4-dioxane --- dynamic --- pollution --- dumping site --- transport phenomena --- superfund --- enhanced reductive dechlorination (ERD) --- dense nonaqueous-phase liquid (DNAPL) --- chlorinated hydrocarbons --- tetrachloroethene (PCE) --- trichloroethene (TCE) --- dichloroethene (DCE) --- anaerobic reduction --- metagenomics --- microplastics --- largemouth bass --- growth --- intestinal morphology --- intestinal microbiota --- PCBs --- monitoring --- biomonitoring --- statistical analysis --- Lake Baikal --- passive sampling --- trace contaminants --- seawater --- chromatography-mass spectrometry --- acute toxicity --- Daphnia magna --- electrochemical oxidation --- emerging contaminants --- methiocarb --- glucocorticoids --- TiO2-solar light degradation --- freshwater pollution --- photoproducts --- matrix constituents --- human health analysis --- water contamination --- water quality model --- hydraulic model --- WDS --- water quality sensors --- agrochemicals --- photo-reactor --- advanced oxidation processes --- water pollution --- point sources --- antioxidant enzymes --- pharmaceutical residues --- pesticides --- detergents --- integrative indexes --- groundwater pollution --- pollution costs --- economic environmental protection instruments --- physico-chemical parameters --- heavy metals --- health risk index --- Pearson coefficients --- adsorption --- dye --- MWCNT --- kinetics --- isotherm models --- thermodynamic --- bioaccumulation --- Lake Chapala --- carp --- catfish --- PTWI --- bioremediation --- ecotoxicology --- Gibbula umbilicalis --- marine bacteria --- tributyltin --- TBT-tolerance --- microalgae --- Vibrio fisheri --- benzenesulfonamide --- benzothiazole --- benzotriazole --- biotoxicity tests --- ferrous lactate --- in situ chemical reduction --- trichloroethylene (TCE) --- green and sustainable remediation (GSR) --- 1,4-dioxane --- dynamic --- pollution --- dumping site --- transport phenomena --- superfund --- enhanced reductive dechlorination (ERD) --- dense nonaqueous-phase liquid (DNAPL) --- chlorinated hydrocarbons --- tetrachloroethene (PCE) --- trichloroethene (TCE) --- dichloroethene (DCE) --- anaerobic reduction --- metagenomics --- microplastics --- largemouth bass --- growth --- intestinal morphology --- intestinal microbiota --- PCBs --- monitoring --- biomonitoring --- statistical analysis --- Lake Baikal --- passive sampling --- trace contaminants --- seawater --- chromatography-mass spectrometry
Choose an application
This book is a collection of a group of peer-reviewed scientific papers dealing with both the evaluation and the solution of the complex but pressing problem of water source pollution. In the case of both fresh and marine water, the environmental and health protection aspects are closely linked. Monitoring activities supply continuous information on the contamination levels in inland surface, ground, and coastal waters, providing an alert in case of increased or new contamination and monitoring the effectiveness of remediation strategies. On the other hand, new or improved remediation and bioremediation tools are urgently needed to tackle the scarcity of safe drinking water. The papers in this book represent interesting starting points for future researches.
Research & information: general --- Chemistry --- acute toxicity --- Daphnia magna --- electrochemical oxidation --- emerging contaminants --- methiocarb --- glucocorticoids --- TiO2-solar light degradation --- freshwater pollution --- photoproducts --- matrix constituents --- human health analysis --- water contamination --- water quality model --- hydraulic model --- WDS --- water quality sensors --- agrochemicals --- photo-reactor --- advanced oxidation processes --- water pollution --- point sources --- antioxidant enzymes --- pharmaceutical residues --- pesticides --- detergents --- integrative indexes --- groundwater pollution --- pollution costs --- economic environmental protection instruments --- physico-chemical parameters --- heavy metals --- health risk index --- Pearson coefficients --- adsorption --- dye --- MWCNT --- kinetics --- isotherm models --- thermodynamic --- bioaccumulation --- Lake Chapala --- carp --- catfish --- PTWI --- bioremediation --- ecotoxicology --- Gibbula umbilicalis --- marine bacteria --- tributyltin --- TBT-tolerance --- microalgae --- Vibrio fisheri --- benzenesulfonamide --- benzothiazole --- benzotriazole --- biotoxicity tests --- ferrous lactate --- in situ chemical reduction --- trichloroethylene (TCE) --- green and sustainable remediation (GSR) --- 1,4-dioxane --- dynamic --- pollution --- dumping site --- transport phenomena --- superfund --- enhanced reductive dechlorination (ERD) --- dense nonaqueous-phase liquid (DNAPL) --- chlorinated hydrocarbons --- tetrachloroethene (PCE) --- trichloroethene (TCE) --- dichloroethene (DCE) --- anaerobic reduction --- metagenomics --- microplastics --- largemouth bass --- growth --- intestinal morphology --- intestinal microbiota --- PCBs --- monitoring --- biomonitoring --- statistical analysis --- Lake Baikal --- passive sampling --- trace contaminants --- seawater --- chromatography–mass spectrometry --- n/a --- chromatography-mass spectrometry
Choose an application
This book is a collection of a group of peer-reviewed scientific papers dealing with both the evaluation and the solution of the complex but pressing problem of water source pollution. In the case of both fresh and marine water, the environmental and health protection aspects are closely linked. Monitoring activities supply continuous information on the contamination levels in inland surface, ground, and coastal waters, providing an alert in case of increased or new contamination and monitoring the effectiveness of remediation strategies. On the other hand, new or improved remediation and bioremediation tools are urgently needed to tackle the scarcity of safe drinking water. The papers in this book represent interesting starting points for future researches.
acute toxicity --- Daphnia magna --- electrochemical oxidation --- emerging contaminants --- methiocarb --- glucocorticoids --- TiO2-solar light degradation --- freshwater pollution --- photoproducts --- matrix constituents --- human health analysis --- water contamination --- water quality model --- hydraulic model --- WDS --- water quality sensors --- agrochemicals --- photo-reactor --- advanced oxidation processes --- water pollution --- point sources --- antioxidant enzymes --- pharmaceutical residues --- pesticides --- detergents --- integrative indexes --- groundwater pollution --- pollution costs --- economic environmental protection instruments --- physico-chemical parameters --- heavy metals --- health risk index --- Pearson coefficients --- adsorption --- dye --- MWCNT --- kinetics --- isotherm models --- thermodynamic --- bioaccumulation --- Lake Chapala --- carp --- catfish --- PTWI --- bioremediation --- ecotoxicology --- Gibbula umbilicalis --- marine bacteria --- tributyltin --- TBT-tolerance --- microalgae --- Vibrio fisheri --- benzenesulfonamide --- benzothiazole --- benzotriazole --- biotoxicity tests --- ferrous lactate --- in situ chemical reduction --- trichloroethylene (TCE) --- green and sustainable remediation (GSR) --- 1,4-dioxane --- dynamic --- pollution --- dumping site --- transport phenomena --- superfund --- enhanced reductive dechlorination (ERD) --- dense nonaqueous-phase liquid (DNAPL) --- chlorinated hydrocarbons --- tetrachloroethene (PCE) --- trichloroethene (TCE) --- dichloroethene (DCE) --- anaerobic reduction --- metagenomics --- microplastics --- largemouth bass --- growth --- intestinal morphology --- intestinal microbiota --- PCBs --- monitoring --- biomonitoring --- statistical analysis --- Lake Baikal --- passive sampling --- trace contaminants --- seawater --- chromatography–mass spectrometry --- n/a --- chromatography-mass spectrometry
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