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The carriers : what the fragile X gene reveals about family,heredity, and scientific discovery
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ISBN: 0231552289 Year: 2022 Publisher: New York : Columbia University Press,

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The Carriers investigates a common but still little-known genetic condition and its life-altering consequences. Anne Skomorowsky reveals how fragile X syndrome afflicts families across generations, telling the stories of the mothers and grandparents of fragile X patients and considering how genes interact with family dynamics.


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Atlas of spinal imaging : phenotypes, measurements, and classification systems
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ISBN: 0323761119 9780323761116 0323761127 Year: 2022 Publisher: Amsterdam, Netherlands ; Kidlington, Oxford ; Cambridge, Massachusetts : Elsevier,

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Spine-related pain is the world's leading disabling condition, affecting every population and a frequent reason for seeking medical consultation and obtaining imaging studies. Numerous spinal phenotypes (observations/traits) and their respective measurements performed on various spine imaging have been shown to directly correlate and predict clinical outcomes. Atlas of Spinal Imaging: Phenotypes, Measurements and Classification Systems is a comprehensive visual resource that highlights various spinal phenotypes on imaging, describes their clinical and pathophysiological relevance, and discusses and illustrates their respective measurement techniques and classifications. Complies the knowledge and expertise of Dr. Dino Samartzis, the preeminent global authority on spinal phenotypes who has discovered and proposed new phenotypes and classification schemes; Dr. Howard S. An, a leading expert in patient management and at the forefront of 3D imaging of various spinal phenotypes; and Dr. Philip Louie, a young surgeon who is involved in one of the largest machine learning initiatives of spinal phenotyping. *Includes a Foreword by renowed spine surgeons Alexander Vaccaro and Max Aebi* Helps readers better understanding spinal phenotypes and their imaging, and how today's knowledge will facilitate new targeted drug discovery, novel diagnostics and biomarker discovery, and outcome predictions. Features step-by-step instructions on performing the radiographic measurements with examples of normal and pathologic images to demonstrate the various presentations. Presents clinical correlation of the phenotypes as well as the radiographic measurements with landmark references. Includes validated classification systems that complement the phenotypes and radiographic measurements. Complies the knowledge and expertise of Dr. Dino Samartzis, the preeminent global authority on spinal phenotypes who has discovered and proposed new phenotypes and classification schemes; Dr. Howard S. An, a leading expert in patient management and at the forefront of 3D imaging of various spinal phenotypes; and Dr. Philip Louie, a prolific surgeon who is involved in one of the largest machine learning initiatives of spinal phenotyping.


Book
Basics of ancient Ethiopic : a complete grammar, workbook, and lexicon
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ISBN: 0310539048 9780310539049 Year: 2022 Publisher: Grand Rapids: Zondervan academic,

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"Basics of Ancient Ethiopic by Archie Wright introduces students to the basic grammar of ancient Ethiopic (Ge'ez) while approaching the language through its wider cultural and literary context, and its historical legacy"--


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Multiscale X-ray Structural Analysis of Cardiac Cells and Tissues
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Year: 2022 Publisher: Universitätsverlag Göttingen

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The cardiac function relies on an intricate molecular and cellular three-dimensional (3d) architecture of a complex, dense and co-dependent cellular network. Structural alterations of the cardiac structure can affect its essential function and lead to severe dysfunction of the organ. Cardiovascular diseases are the main cause of death worldwide with a rising incidence.However, it is not possible to give a generalized answer how the heart is formed. Up to now, cardiac structure as well as physiologic and disease-related tissue alterations of the tissue are mainly investigated by established 2d imaging methods such as optical microscopy or electron microscopy.This work presents a multiscale and multimodal X-ray imaging approach, which allows to probe the heart structure from the scale of entire intact murine hearts to the molecular organisation of the sarcomer structure.While the molecular structure of the actomyosin complex is probed by scanning X-ray diffraction,the 3d arrangement of the cellular network is investigated by propagation-based X-ray phase-contrast tomography. In this context, the concept of 3d virtual histology of cardiac tissue by X-ray phase-contrast tomography using laboratory sources as well as highly coherent synchrotron radiation is being further developed.


Book
Multiscale X-ray Structural Analysis of Cardiac Cells and Tissues
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Year: 2022 Publisher: Universitätsverlag Göttingen

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The cardiac function relies on an intricate molecular and cellular three-dimensional (3d) architecture of a complex, dense and co-dependent cellular network. Structural alterations of the cardiac structure can affect its essential function and lead to severe dysfunction of the organ. Cardiovascular diseases are the main cause of death worldwide with a rising incidence.However, it is not possible to give a generalized answer how the heart is formed. Up to now, cardiac structure as well as physiologic and disease-related tissue alterations of the tissue are mainly investigated by established 2d imaging methods such as optical microscopy or electron microscopy.This work presents a multiscale and multimodal X-ray imaging approach, which allows to probe the heart structure from the scale of entire intact murine hearts to the molecular organisation of the sarcomer structure.While the molecular structure of the actomyosin complex is probed by scanning X-ray diffraction,the 3d arrangement of the cellular network is investigated by propagation-based X-ray phase-contrast tomography. In this context, the concept of 3d virtual histology of cardiac tissue by X-ray phase-contrast tomography using laboratory sources as well as highly coherent synchrotron radiation is being further developed.


Book
Imaging of Tuberculosis
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ISBN: 9783031070402 Year: 2022 Publisher: Cham Springer International Publishing :Imprint: Springer

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Keywords

Tuberculosis, Pulmonary$xdiagnostic imaging --- Tomography, X-Ray Computed --- Tuberculosis --- Tuberculosis, Pulmonary --- diagnostic imaging --- Antitubercular Agents --- Tuberculin Test --- Interferon-gamma Release Tests --- Koch's Disease --- Kochs Disease --- Mycobacterium tuberculosis Infection --- Infection, Mycobacterium tuberculosis --- Infections, Mycobacterium tuberculosis --- Koch Disease --- Mycobacterium tuberculosis Infections --- Tuberculoses --- Colonography, Computed Tomographic --- CAT Scan, X Ray --- CT X Ray --- Computed Tomography, X-Ray --- Computed X Ray Tomography --- Computerized Tomography, X Ray --- Electron Beam Tomography --- Tomography, X Ray Computed --- Tomography, X-Ray Computer Assisted --- Tomography, X-Ray Computerized --- Tomography, X-Ray Computerized Axial --- Tomography, Xray Computed --- X Ray Computerized Tomography --- X Ray Tomography, Computed --- X-Ray Computer Assisted Tomography --- X-Ray Computerized Axial Tomography --- CAT Scan, X-Ray --- CT Scan, X-Ray --- Cine-CT --- Computerized Tomography, X-Ray --- Electron Beam Computed Tomography --- Tomodensitometry --- Tomography, Transmission Computed --- X-Ray Tomography, Computed --- Beam Tomography, Electron --- CAT Scans, X-Ray --- CT Scan, X Ray --- CT Scans, X-Ray --- CT X Rays --- Cine CT --- Computed Tomography, Transmission --- Computed Tomography, X Ray --- Computed Tomography, Xray --- Computed X-Ray Tomography --- Scan, X-Ray CAT --- Scan, X-Ray CT --- Scans, X-Ray CAT --- Scans, X-Ray CT --- Tomographies, Computed X-Ray --- Tomography, Computed X-Ray --- Tomography, Electron Beam --- Tomography, X Ray Computer Assisted --- Tomography, X Ray Computerized --- Tomography, X Ray Computerized Axial --- Transmission Computed Tomography --- X Ray Computer Assisted Tomography --- X Ray Computerized Axial Tomography --- X Ray, CT --- X Rays, CT --- X-Ray CAT Scan --- X-Ray CAT Scans --- X-Ray CT Scan --- X-Ray CT Scans --- X-Ray Computed Tomography --- X-Ray Computerized Tomography --- Xray Computed Tomography --- Imaging. --- Treatment. --- Consumption (Disease) --- Lungs --- Phthisis --- Pulmonary tuberculosis --- TB (Disease) --- Chest --- Mycobacterial diseases --- Mycobacterium tuberculosis --- Diseases


Book
Multiscale X-ray Structural Analysis of Cardiac Cells and Tissues
Author:
Year: 2022 Publisher: Universitätsverlag Göttingen

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Abstract

The cardiac function relies on an intricate molecular and cellular three-dimensional (3d) architecture of a complex, dense and co-dependent cellular network. Structural alterations of the cardiac structure can affect its essential function and lead to severe dysfunction of the organ. Cardiovascular diseases are the main cause of death worldwide with a rising incidence.However, it is not possible to give a generalized answer how the heart is formed. Up to now, cardiac structure as well as physiologic and disease-related tissue alterations of the tissue are mainly investigated by established 2d imaging methods such as optical microscopy or electron microscopy.This work presents a multiscale and multimodal X-ray imaging approach, which allows to probe the heart structure from the scale of entire intact murine hearts to the molecular organisation of the sarcomer structure.While the molecular structure of the actomyosin complex is probed by scanning X-ray diffraction,the 3d arrangement of the cellular network is investigated by propagation-based X-ray phase-contrast tomography. In this context, the concept of 3d virtual histology of cardiac tissue by X-ray phase-contrast tomography using laboratory sources as well as highly coherent synchrotron radiation is being further developed.


Book
Harnessing materials for x-ray based cancer therapy and imaging
Authors: --- ---
ISBN: 3031040708 3031040716 Year: 2022 Publisher: Cham, Switzerland : Springer,

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Book
Hope and Fear : modern myths, conspiracy theories and pseudo-history
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ISBN: 1789145392 9781789145397 Year: 2022 Publisher: London: Reaktion books,

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Book
Neutron and X-Ray Reflectometry : Emerging Phenomena at Heterostructure Interfaces
Authors: --- ---
ISBN: 0750346949 0750346957 Year: 2022 Publisher: Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing,

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This book presents x-ray and neutron reflectometry techniques and how they can be used to explore interface structure and magnetism at mesoscopic length scale in thin films and multilayers.

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