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Histopathological studies of aquatic animals refer to the microscopic examination of tissues and organs in order to detect deviations from the expected microscopic or macroscopic structure. Information obtained from the study of histomorphological lesions in aquatic animals can be a useful addition when determining the general state of health of aquatic animals, especially if chronic stressors and/or pathogens are present. Compared to mammals, postmortem autolysis progresses very rapidly in most aquatic organisms. This fact makes histopathological examination quite complex and demanding, not only in a histotechnical sense. A prerequisite for a successful study is the baseline knowledge of physiological processes and histological architecture of the studied species. Therefore, the aim of this Special Issue is to contribute to the current state of knowledge on the histopathology of aquatic animals and to provide a professional and encyclopedic tool for biologists and veterinarians.

Research & information: general --- Biology, life sciences --- Fisheries & related industries --- micro-nano plastics --- fish --- organism model --- histopathology --- blood biomarkers --- microlipoma --- liver --- Barbus balcanicus --- 3D reconstruction --- nutrition --- aquaculture --- fishmeal replacement --- land animal proteins --- histology --- intestinal microbiota --- Sparus aurata --- toxicity --- effect --- invertebrate --- mussels --- Aeromonas spp. --- rainbow trout --- bacteria --- infection --- antinutritional factors --- soybean --- gut health --- environmental monitoring --- histopathological biomarkers --- histopathological alterations --- fish gills --- atrazine --- Purkinje --- cerebellum --- myocytes --- toxicology --- IP3Rs --- Vistonis Lake --- physico-chemical parameters --- gills --- HSPs --- MARKs --- Na+-K+ ATPase --- hepatorenal --- pathology --- toxicosis --- biomarkers --- adult Xenopus laevis --- micro-nano plastics --- fish --- organism model --- histopathology --- blood biomarkers --- microlipoma --- liver --- Barbus balcanicus --- 3D reconstruction --- nutrition --- aquaculture --- fishmeal replacement --- land animal proteins --- histology --- intestinal microbiota --- Sparus aurata --- toxicity --- effect --- invertebrate --- mussels --- Aeromonas spp. --- rainbow trout --- bacteria --- infection --- antinutritional factors --- soybean --- gut health --- environmental monitoring --- histopathological biomarkers --- histopathological alterations --- fish gills --- atrazine --- Purkinje --- cerebellum --- myocytes --- toxicology --- IP3Rs --- Vistonis Lake --- physico-chemical parameters --- gills --- HSPs --- MARKs --- Na+-K+ ATPase --- hepatorenal --- pathology --- toxicosis --- biomarkers --- adult Xenopus laevis

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Neuroactive chemicals are the largest group of micropollutants present in European rivers. There is increasing concern about the behavioral effects of these neuroactive chemicals on aquatic wildlife, potentially resulting in detrimental effects on individual, population, and community levels of ecological organization. This Special Issue, titled “Behavioral Impairment in Aquatic Organisms Exposed to Neurotoxic Pollutants”, presents original research and review articles addressing behavioral impairment induced by different aquatic invertebrate and vertebrate species to neuroactive chemicals. The selected studies include different methodological approaches, such as multi-compartment, automated plug and play, and homemade setups systems. We believe that this collection provides essential information regarding research and challenges on the behavioral ecotoxicity of invertebrate and vertebrate aquatic organisms, as well as the molecular mechanisms behind these effects.

avoidance --- behavior --- habitat selection --- multi-compartmented systems --- non-forced exposure --- repellency --- natural products --- fungicides --- early development --- teratogenicity --- zebrafish --- behaviour --- oxidative stress --- ecotoxicology --- artemia --- psychotropics --- behavioural ecotoxicology --- mixture toxicity --- neurotoxicity --- antagonism --- organophosphate --- acetylcholinesterase inhibitors --- GABA --- risk assessment --- spontaneous movement activity --- zebrafish larvae --- serotonin --- neurotransmitters --- modulation --- copper --- glyphosate --- chlorpyrifos --- early life stages --- rainbow trout --- swimming behavior --- DNA damage --- development --- Daphnia magna --- neurotransmitter --- pharmaceuticals --- pharmaceuticals in the environment --- environmental risk assessment --- fish --- mixture toxicology --- predictive toxicology --- pollution --- n/a