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In the medical world, research autopsies are becoming increasingly significant. Since 2012, the term "research autopsy" has become incredibly common. Finding a suitable definition for a research autopsy is therefore of great importance. As a result, a large part of this thesis will be devoted to defining this term. Second, the literature frequently refers to a rapid autopsy program, in which research autopsies provide a comprehensive understanding of the extent of a disease. These rapid autopsy programs also allow for the collection of fresh tissue samples from all affected organs within hours of a patient's death. Furthermore, it is critical to understand how a rapid autopsy program in which a research autopsy is performed is launched in Belgium, as well as the conditions that must be met. Legislation and the ethics committee are significant in this regard. as well as how to recruit patients into the program. Finally, the many studies that appear in the literature, both internationally and at UZ/KU Leuven, are thoroughly examined. The international studies are reviewed in light of the extensive literature research. Concerning the studies at UZ/KU Leuven, the focus will be on the autopsy that are presently being conducted in the context of scientific research at the UZ/KU Leuven.