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Development of new drug molecules is costly and requires longitudinal, wide-ranging studies; therefore, designing advanced pharmaceutical formulations for existing and well-known drugs seems to be an attractive device for the pharmaceutical industry. Properly formulated drug delivery systems can improve pharmacological activity, efficacy and safety of the active substances. Advanced materials applied as pharmaceutical excipients in designing drug delivery systems can help solve problems concerning the required drug release—with the defined dissolution rate and at the determined site. Novel drug carriers enable more effective drug delivery, with improved safety and with fewer side effects. Investigations concerning advanced materials represent a rapidly growing research field in material/polymer science, chemical engineering and pharmaceutical technology. Exploring novel materials or modifying and combining existing ones is now a crucial trend in pharmaceutical technology. Eleven articles included in the the Special Issue “Advanced Materials in Drug Release and Drug Delivery Systems” present the most recent insights into the utilization of different materials with promising potential in drug delivery and into different formulation approaches that can be used in the design of pharmaceutical formulations.

Technology: general issues --- mesoporous silica --- layer-by-layer --- FITC-peptide --- hyaluronic acid --- multilayer film --- host-guest interaction --- total alkaloids from Alstonia scholaris leaves --- mPEG-PLA --- microspheres --- drug release --- biocompatibility --- CO administration --- therapeutic agent --- pharmaceutical drugs --- heme oxygenase --- CO-releasing materials --- CO-releasing molecules --- organometallic complexes --- pharmacokinetic functions --- pathological role --- CO kinetic profile --- cellular targets --- GQDs --- real-time tracking --- optical-magneto nanoparticles --- in vivo --- ethylcellulose --- polymeric material --- cellulose derivative --- pharmaceutical excipient --- hydrogel --- drug delivery --- polymer --- immobilization of drug --- gelatin --- gastro-resistant --- films --- capsules --- structure --- sirolimus --- electrospinning --- polycaprolactone --- 3D matrix --- drug-eluting stents --- spray drying --- microparticles --- rupatadine fumarate --- orodispersible minitablets --- taste masking --- Bicalutamide --- Poloxamer® 407 --- Macrogol 6000 --- supercritical carbon dioxide --- solid dispersions --- dissolution rate --- amorphization --- 3D printing --- fused deposition modeling --- hot-melt extrusion --- solid dosage forms --- itraconazole --- mesoporous silica --- layer-by-layer --- FITC-peptide --- hyaluronic acid --- multilayer film --- host-guest interaction --- total alkaloids from Alstonia scholaris leaves --- mPEG-PLA --- microspheres --- drug release --- biocompatibility --- CO administration --- therapeutic agent --- pharmaceutical drugs --- heme oxygenase --- CO-releasing materials --- CO-releasing molecules --- organometallic complexes --- pharmacokinetic functions --- pathological role --- CO kinetic profile --- cellular targets --- GQDs --- real-time tracking --- optical-magneto nanoparticles --- in vivo --- ethylcellulose --- polymeric material --- cellulose derivative --- pharmaceutical excipient --- hydrogel --- drug delivery --- polymer --- immobilization of drug --- gelatin --- gastro-resistant --- films --- capsules --- structure --- sirolimus --- electrospinning --- polycaprolactone --- 3D matrix --- drug-eluting stents --- spray drying --- microparticles --- rupatadine fumarate --- orodispersible minitablets --- taste masking --- Bicalutamide --- Poloxamer® 407 --- Macrogol 6000 --- supercritical carbon dioxide --- solid dispersions --- dissolution rate --- amorphization --- 3D printing --- fused deposition modeling --- hot-melt extrusion --- solid dosage forms --- itraconazole

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Absorbable metals have shown significant clinical potential for temporary implant applications, where the material is eventually replaced by healthy, functioning tissue. However, several challenges remain before these metals can be used in humans. Innovations and further improvements are required. This book collects scientific contributions dealing with the development of absorbable metals with improved and unique corrosion and mechanical properties for applications in highly loaded implants or cardiovascular and urethral stents.

surface treatments --- roughness --- Mg-alloys --- degradation behavior --- absorbable --- corrosion --- degradation --- magnesium --- ureteral stent --- zinc --- mandibular condylar fracture --- unsintered hydroxyapatite/poly-l-lactide composite plate --- bioactive resorbable plate --- biomechanical loading evaluation --- fracture fixation --- WE43/HA composite --- friction stir processing --- microstructure --- mechanical properties --- corrosion behavior --- absorbable metal --- cytotoxicity --- stent --- ureteral --- urothelial cells --- zinc alloy --- poly-L-lactide --- uncalcined and unsintered hydroxyapatite --- biocompatibility --- osteoconductivity --- mesenchymal stem cell --- iron foam --- polyethyleneimine (PEI) --- biodegradation --- powder metallurgy --- coating --- biodegradable magnesium implants --- bioceramics --- bioactivity --- orthopedic implant --- bone surgery --- absorbable implants --- magnesium (Mg) --- oral and maxillofacial --- orthopedic --- titanium (Ti) --- biomaterials --- electrochemistry --- hydrogen evolution --- microscopy --- Mg-Zn-Sn alloy --- osteoinductive activity --- sirolimus --- rabbit coronary artery endothelial cells --- smooth muscle cells --- bioabsorbable metals --- in-vivo biocompatibility --- strontium --- toxicity --- systemic reactions --- alloy accumulation --- internal organs --- iron --- corrosion rate --- biodegradable material --- n/a

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• Reference Manager
• EndNote
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Development of new drug molecules is costly and requires longitudinal, wide-ranging studies; therefore, designing advanced pharmaceutical formulations for existing and well-known drugs seems to be an attractive device for the pharmaceutical industry. Properly formulated drug delivery systems can improve pharmacological activity, efficacy and safety of the active substances. Advanced materials applied as pharmaceutical excipients in designing drug delivery systems can help solve problems concerning the required drug release—with the defined dissolution rate and at the determined site. Novel drug carriers enable more effective drug delivery, with improved safety and with fewer side effects. Investigations concerning advanced materials represent a rapidly growing research field in material/polymer science, chemical engineering and pharmaceutical technology. Exploring novel materials or modifying and combining existing ones is now a crucial trend in pharmaceutical technology. Eleven articles included in the the Special Issue “Advanced Materials in Drug Release and Drug Delivery Systems” present the most recent insights into the utilization of different materials with promising potential in drug delivery and into different formulation approaches that can be used in the design of pharmaceutical formulations.

mesoporous silica --- layer-by-layer --- FITC-peptide --- hyaluronic acid --- multilayer film --- host-guest interaction --- total alkaloids from Alstonia scholaris leaves --- mPEG-PLA --- microspheres --- drug release --- biocompatibility --- CO administration --- therapeutic agent --- pharmaceutical drugs --- heme oxygenase --- CO-releasing materials --- CO-releasing molecules --- organometallic complexes --- pharmacokinetic functions --- pathological role --- CO kinetic profile --- cellular targets --- GQDs --- real-time tracking --- optical-magneto nanoparticles --- in vivo --- ethylcellulose --- polymeric material --- cellulose derivative --- pharmaceutical excipient --- hydrogel --- drug delivery --- polymer --- immobilization of drug --- gelatin --- gastro-resistant --- films --- capsules --- structure --- sirolimus --- electrospinning --- polycaprolactone --- 3D matrix --- drug-eluting stents --- spray drying --- microparticles --- rupatadine fumarate --- orodispersible minitablets --- taste masking --- Bicalutamide --- Poloxamer® 407 --- Macrogol 6000 --- supercritical carbon dioxide --- solid dispersions --- dissolution rate --- amorphization --- 3D printing --- fused deposition modeling --- hot-melt extrusion --- solid dosage forms --- itraconazole --- n/a