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book (6)


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English (6)


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2021 (6)

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Book
Prevention and Treatment of Sarcopenia
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Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Sarcopenia represents the decline in skeletal muscle mass and function with age, characterized by the muscle fiber's quality, strength, muscle endurance, and metabolic ability decreasing, as well as the fat and connective tissue growing.Reduction of muscle strength with aging leads to loss of functional capacity, causing disability, mortality, and other adverse health outcomes. Because of the increase of the proportion of elderly in the population, sarcopenia-related morbidity will become an increasing area of health care resource utilization.Diagnostic screening consists of individuation of body composition, assessed by DEXA, anthropometry, bioelectrical impedance, MRI, or CT scan. Management is possible with resistance training exercise and vibration therapy, nutritional supplements, and pharmacological treatment.The book includes articles from different nationalities, treating the experimental and medical applications of sarcopenia. The consequences of sarcopenia in frailty are treated in relation to other associated pathologies or lesions, as femoral neck fractures and hepatocellular carcinoma.

Keywords

Medicine --- muscle-mass --- sleep efficiency --- sleep duration --- insomnia --- sarcopenia --- quality of life --- osteoporosis --- postmenopausal women --- sedentary behaviour --- aged --- exercise --- motivation --- hepatoma --- myokine --- decorin --- walking distance --- survival --- muscle strength --- resistance training --- randomized controlled trial --- nutritional status --- nutritional screening tools --- hospitalized older patients --- resistance exercise training --- muscle regulatory factors --- deconditioning --- skeletal muscle --- elderly --- hypertrophy --- multimorbidity --- polypathological patients --- frailty --- oxidative stress --- telomere length --- apoptosis --- spirometry --- urea --- fatigue --- respiratory system --- skeletal muscles --- lipids --- transaminases --- falls --- resistance exercise --- vibration --- electrical stimulation --- hip fracture --- diagnosis --- treatment --- prevention --- dual-energy X-ray absorptiometry --- bisphosphonate --- β-hydroxy-β-methylbutyrate --- exercise intervention --- fall risk --- balance --- anxiety --- depression --- sleep quality --- type 2 diabetes --- physical activity --- muscle mass --- protein intake --- accelerometer --- aerobic exercise training --- mitochondria --- endurance --- fractures --- ageing fractures --- complications --- recovery --- rehabilitation --- nutritional supplements --- physical therapy --- cognition --- brain-body cross-talk --- older persons --- prevalence --- physical functional performance --- epidemiologic studies --- aging --- panoramic ultrasound --- echogenicity --- specific force --- isokinetic dynamometry --- muscle quality --- strength --- older adults --- diagnostic criteria --- clinical


Book
Asthma : Current Perspectives on Phenotypes, Endotypes, and Treatable Traits
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Asthma is a common complex and heterogeneous respiratory disease with an increasing prevalence in developed countries. Asthma is a disease consisting of different phenotypes that are driven by different mechanistic pathways (endotypes). The recognition of these phenotypes and endotypes is central to asthma management entailing prognostic and therapeutic implications. It is acknowledged that despite optimal treatment, many patients are poorly controlled, highlighting the need for phenotype-guided treatments. In this context, the emergence of novel therapies (monoclonal antibody therapy, bronchial thermoplasty) is paving the way for personalized asthma therapy. A better understanding of disease pathogenesis may enable the identification of biomarkers, mediators, novel therapeutic targets, and treatable traits. Further molecular phenotyping or endotyping of asthma will be necessary to tailor new therapeutic strategies. The present Special Issue on Asthma aims to provide the current knowledge on phenotypes and endotypes in appreciating and managing the heterogeneous condition that is asthma.


Book
Prevention and Treatment of Sarcopenia
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Bookmark

Abstract

Sarcopenia represents the decline in skeletal muscle mass and function with age, characterized by the muscle fiber's quality, strength, muscle endurance, and metabolic ability decreasing, as well as the fat and connective tissue growing.Reduction of muscle strength with aging leads to loss of functional capacity, causing disability, mortality, and other adverse health outcomes. Because of the increase of the proportion of elderly in the population, sarcopenia-related morbidity will become an increasing area of health care resource utilization.Diagnostic screening consists of individuation of body composition, assessed by DEXA, anthropometry, bioelectrical impedance, MRI, or CT scan. Management is possible with resistance training exercise and vibration therapy, nutritional supplements, and pharmacological treatment.The book includes articles from different nationalities, treating the experimental and medical applications of sarcopenia. The consequences of sarcopenia in frailty are treated in relation to other associated pathologies or lesions, as femoral neck fractures and hepatocellular carcinoma.

Keywords

muscle-mass --- sleep efficiency --- sleep duration --- insomnia --- sarcopenia --- quality of life --- osteoporosis --- postmenopausal women --- sedentary behaviour --- aged --- exercise --- motivation --- hepatoma --- myokine --- decorin --- walking distance --- survival --- muscle strength --- resistance training --- randomized controlled trial --- nutritional status --- nutritional screening tools --- hospitalized older patients --- resistance exercise training --- muscle regulatory factors --- deconditioning --- skeletal muscle --- elderly --- hypertrophy --- multimorbidity --- polypathological patients --- frailty --- oxidative stress --- telomere length --- apoptosis --- spirometry --- urea --- fatigue --- respiratory system --- skeletal muscles --- lipids --- transaminases --- falls --- resistance exercise --- vibration --- electrical stimulation --- hip fracture --- diagnosis --- treatment --- prevention --- dual-energy X-ray absorptiometry --- bisphosphonate --- β-hydroxy-β-methylbutyrate --- exercise intervention --- fall risk --- balance --- anxiety --- depression --- sleep quality --- type 2 diabetes --- physical activity --- muscle mass --- protein intake --- accelerometer --- aerobic exercise training --- mitochondria --- endurance --- fractures --- ageing fractures --- complications --- recovery --- rehabilitation --- nutritional supplements --- physical therapy --- cognition --- brain-body cross-talk --- older persons --- prevalence --- physical functional performance --- epidemiologic studies --- aging --- panoramic ultrasound --- echogenicity --- specific force --- isokinetic dynamometry --- muscle quality --- strength --- older adults --- diagnostic criteria --- clinical


Book
Asthma : Current Perspectives on Phenotypes, Endotypes, and Treatable Traits
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

Asthma is a common complex and heterogeneous respiratory disease with an increasing prevalence in developed countries. Asthma is a disease consisting of different phenotypes that are driven by different mechanistic pathways (endotypes). The recognition of these phenotypes and endotypes is central to asthma management entailing prognostic and therapeutic implications. It is acknowledged that despite optimal treatment, many patients are poorly controlled, highlighting the need for phenotype-guided treatments. In this context, the emergence of novel therapies (monoclonal antibody therapy, bronchial thermoplasty) is paving the way for personalized asthma therapy. A better understanding of disease pathogenesis may enable the identification of biomarkers, mediators, novel therapeutic targets, and treatable traits. Further molecular phenotyping or endotyping of asthma will be necessary to tailor new therapeutic strategies. The present Special Issue on Asthma aims to provide the current knowledge on phenotypes and endotypes in appreciating and managing the heterogeneous condition that is asthma.


Book
Prevention and Treatment of Sarcopenia
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

Sarcopenia represents the decline in skeletal muscle mass and function with age, characterized by the muscle fiber's quality, strength, muscle endurance, and metabolic ability decreasing, as well as the fat and connective tissue growing.Reduction of muscle strength with aging leads to loss of functional capacity, causing disability, mortality, and other adverse health outcomes. Because of the increase of the proportion of elderly in the population, sarcopenia-related morbidity will become an increasing area of health care resource utilization.Diagnostic screening consists of individuation of body composition, assessed by DEXA, anthropometry, bioelectrical impedance, MRI, or CT scan. Management is possible with resistance training exercise and vibration therapy, nutritional supplements, and pharmacological treatment.The book includes articles from different nationalities, treating the experimental and medical applications of sarcopenia. The consequences of sarcopenia in frailty are treated in relation to other associated pathologies or lesions, as femoral neck fractures and hepatocellular carcinoma.

Keywords

Medicine --- muscle-mass --- sleep efficiency --- sleep duration --- insomnia --- sarcopenia --- quality of life --- osteoporosis --- postmenopausal women --- sedentary behaviour --- aged --- exercise --- motivation --- hepatoma --- myokine --- decorin --- walking distance --- survival --- muscle strength --- resistance training --- randomized controlled trial --- nutritional status --- nutritional screening tools --- hospitalized older patients --- resistance exercise training --- muscle regulatory factors --- deconditioning --- skeletal muscle --- elderly --- hypertrophy --- multimorbidity --- polypathological patients --- frailty --- oxidative stress --- telomere length --- apoptosis --- spirometry --- urea --- fatigue --- respiratory system --- skeletal muscles --- lipids --- transaminases --- falls --- resistance exercise --- vibration --- electrical stimulation --- hip fracture --- diagnosis --- treatment --- prevention --- dual-energy X-ray absorptiometry --- bisphosphonate --- β-hydroxy-β-methylbutyrate --- exercise intervention --- fall risk --- balance --- anxiety --- depression --- sleep quality --- type 2 diabetes --- physical activity --- muscle mass --- protein intake --- accelerometer --- aerobic exercise training --- mitochondria --- endurance --- fractures --- ageing fractures --- complications --- recovery --- rehabilitation --- nutritional supplements --- physical therapy --- cognition --- brain-body cross-talk --- older persons --- prevalence --- physical functional performance --- epidemiologic studies --- aging --- panoramic ultrasound --- echogenicity --- specific force --- isokinetic dynamometry --- muscle quality --- strength --- older adults --- diagnostic criteria --- clinical


Book
Asthma : Current Perspectives on Phenotypes, Endotypes, and Treatable Traits
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

Asthma is a common complex and heterogeneous respiratory disease with an increasing prevalence in developed countries. Asthma is a disease consisting of different phenotypes that are driven by different mechanistic pathways (endotypes). The recognition of these phenotypes and endotypes is central to asthma management entailing prognostic and therapeutic implications. It is acknowledged that despite optimal treatment, many patients are poorly controlled, highlighting the need for phenotype-guided treatments. In this context, the emergence of novel therapies (monoclonal antibody therapy, bronchial thermoplasty) is paving the way for personalized asthma therapy. A better understanding of disease pathogenesis may enable the identification of biomarkers, mediators, novel therapeutic targets, and treatable traits. Further molecular phenotyping or endotyping of asthma will be necessary to tailor new therapeutic strategies. The present Special Issue on Asthma aims to provide the current knowledge on phenotypes and endotypes in appreciating and managing the heterogeneous condition that is asthma.

Listing 1 - 6 of 6
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