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Highly visual and easy to navigate, OCT and OCT Angiography in Retinal Disorders is a concise, reliable reference for optical coherence tomography (OCT) and OCT angiography findings in both common and uncommon retinal disorders. Each chapter explores the prognostic features of OCT and OCTA scans along with additional diagnostic modalities for comparison and correlation. Where appropriate, longitudinal changes in response to treatment or natural history are also discussed. Includes hundreds of high-quality, striking images. Highlights the salient imaging features of the clinical entity or entities being discussed. Covers OCT technology, techniques, and scanning patterns. Provides concise, authoritative guidance on numerous key areas in retinal disease, including retinal vascular disease, inflammation, retinal degenerations and dystrophies, ocular trauma ocular tumors, and much more.

Retinal Diseases --- Tomography, Optical Coherence --- Retinal Vessels --- Angiography --- Diagnostic Techniques, Ophthalmological --- diagnostic imaging --- methods

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The concept of advanced therapy medicinal products (ATMPs) encompasses novel kinds of medicines for human use that are based on genes, cells or tissues. These intend to offer not only regeneration, but complete functional recovery of diseased tissues and organs using different strategies. Gene therapy, cell therapy and tissue engineering are the main areas in which promising advanced therapies are emerging. The eye is a very complex organ whose main structures, the cornea and the retina, play a pivotal role in maintaining normal vision, as severe alterations in these tissues can lead to blindness. Ocular tissues are starting to benefit from ATMPs by fighting against the enormous complexity and devastating potential of many ocular diseases. However, developments arising from this field of work face important challenges related to vectors to deliver drugs and genetic material to target tissues, suitable biomaterials to prepare cell scaffolds and cell stemness, among others—not to mention the complicated legislation around ATMPs, the complexity in production and quality control and the absence of standardized protocols.The purpose of this Special Issue is to serve as an overview of the current progress in the application of cell and gene therapies, as well as tissue engineering to restore functionality in diseased ocular structures, and the challenges linked to reaching patients.

Medicine --- MPC polymer --- dry eye --- ocular surface --- lacrimal fluid --- mucin --- 3D bioprinting --- cornea --- retina --- ophthalmology --- tissue regeneration --- electrospinning --- conjunctiva --- decellularized tissue matrix --- small intestinal submucosa --- urinary bladder matrix --- polycaprolactone --- fiber --- tissue engineering --- stratification --- conjunctival epithelial cells --- hydrogel --- keratoplasty --- scaffold --- collagen --- advanced therapy medicinal product --- ATMP --- cell therapy --- gene therapy --- eye --- ocular --- regulatory --- marketing authorization --- double-crosslinking --- carbodiimide --- glutaraldehyde --- sodium metabisulfite --- sodium borohydride --- EDC/NHS --- stem cells --- retinal diseases --- optic nerve diseases --- cell replacement --- cell sources --- advanced therapies --- ocular mucosa --- blindness --- CLET --- limbal niche --- limbal stem cell --- LSCD --- mesenchymal stem cell transplantation --- MSCT --- corneal limbus --- decellularized xenograft --- recellularization --- mesenchymal stem cells