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Biogenic amines are bioactive compounds distributed in foods of all origins. Apart from their fundamental role in many bodily functions, there has recently been great interest in their toxicological potential, much research is being carried out to understand their occurrence related to both desired and undesired fermentative phenomena, chemical spoilage, low hygienic conditions, wrong handling, and criticism about technological factors of process and storage conditions. All these causes can contribute to a higher content of biogenic amines in food, particularly of those hazardous to human health. This book aims to collect scientific studies looking for new tools to limit the over-production of biogenic amines in food, search for new food sources of biogenic amines, and to spotlight the concept of safe food and bioactive amines content.

Research & information: general --- cocoa nibs --- roasting --- bioactive amines --- polyphenols --- volatile organic compounds --- geographical areas --- biogenic amines --- L. plantarum --- amines oxidase --- Chinese rice wine --- industrial fermentation --- nigiri sushi --- polycyclic aromatic hydrocarbons --- histamine --- household smoker unit --- kimchi --- Jeotgal --- Aekjeot --- Myeolchi-jeot --- Myeolchi-aekjeot --- recommended limits --- occurrence --- reduction --- starter cultures --- biogenic amine --- maesil --- amino acids --- soaking --- fermentation --- temperature --- Cambodian fermented foods --- microbial characteristics --- food quality --- food safety --- microbiota --- Cheonggukjang --- Enterococcus faecium --- tyramine --- fermentation temperature --- fermentation duration --- tyrosine decarboxylase gene (tdc) --- proteolysis --- dry fermented sausage --- casing --- volatile compounds --- texture --- low temperature --- dried milkfish --- hygienic quality --- brine-salting --- biogenic amines (BAs) --- fermented foods --- chemometrics --- multivariate (MV) statistical analysis --- liquid chromatographic triple quadrupole mass spectrometric (LC-MS/MS) analysis --- public health --- lipid peroxidation --- antioxidants --- cocoa nibs --- roasting --- bioactive amines --- polyphenols --- volatile organic compounds --- geographical areas --- biogenic amines --- L. plantarum --- amines oxidase --- Chinese rice wine --- industrial fermentation --- nigiri sushi --- polycyclic aromatic hydrocarbons --- histamine --- household smoker unit --- kimchi --- Jeotgal --- Aekjeot --- Myeolchi-jeot --- Myeolchi-aekjeot --- recommended limits --- occurrence --- reduction --- starter cultures --- biogenic amine --- maesil --- amino acids --- soaking --- fermentation --- temperature --- Cambodian fermented foods --- microbial characteristics --- food quality --- food safety --- microbiota --- Cheonggukjang --- Enterococcus faecium --- tyramine --- fermentation temperature --- fermentation duration --- tyrosine decarboxylase gene (tdc) --- proteolysis --- dry fermented sausage --- casing --- volatile compounds --- texture --- low temperature --- dried milkfish --- hygienic quality --- brine-salting --- biogenic amines (BAs) --- fermented foods --- chemometrics --- multivariate (MV) statistical analysis --- liquid chromatographic triple quadrupole mass spectrometric (LC-MS/MS) analysis --- public health --- lipid peroxidation --- antioxidants

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This Special Issue is a collection of research articles focused on the production and role of nitric oxide in plants. Nitric oxide is a crucial molecule used in the orchestration of cellular events in animals and plants. With a mixture of primary research papers and review articles written by some of the top researchers in the field, this work encompasses many aspects of this important and growing area of biochemistry.

Research & information: general --- Biology, life sciences --- catalase --- monodehydroascorbate reductase --- tyrosine nitration --- nitric oxide --- peroxisome --- reactive oxygen species --- S-nitrosation --- superoxide dismutase --- antioxidants --- hydrogen gas --- hydrogen peroxide --- hydrogen sulfide --- S-nitrosothiols --- S-nitrosoglutathione reductase --- S-(hydroxymethyl)glutathione --- nitrate reductase --- NOFNiR --- nitrogen metabolism --- NIA1 --- NIA2 --- nitrite --- nitrate --- methyl viologen --- benzyl viologen --- NO analyzer --- molybdenum cofactor --- Arabidopsis thaliana --- nitro-fatty acids --- nitroalkenes --- nitroalkylation --- electrophile --- nucleophile --- signaling mechanism --- post-translational modification --- reactive lipid species --- nitro-lipid-protein adducts --- Trebouxia --- microalgae --- lipid peroxidation --- diaphorase activity --- lichens --- nitric oxide synthase --- nitrogen dioxide --- plant growth --- cell enlargement --- cell proliferation --- early flowering --- PsbO --- nitric oxide homeostasis --- cue1/nox1 --- reactive nitrogen species --- germination --- root development --- stress responses --- sugar metabolism --- nitration --- S-nitrosylation --- SNO-reductase --- thiol modification

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The G.B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far-Eastern Branch of the Russian Academy of Sciences (PIBOC FEB RAS) was founded in 1964 in Vladivostok in the Far East of Russia. Over many years, we have been carrying out studies on the natural products of both marine and terrestrial origin. In collaboration with many Russian and foreign scientists, we have investigated many hundreds of diverse biomolecules, including steroids and terpenoids, quinoid compounds and alkaloids, polysaccharides and lipids, enzymes and lectins, proteins, and peptides. The Institute has a collection of marine microorganisms (KMM) PIBOC, which includes more than 4000 strains of marine bacteria and more than 1000 strains of marine fungi. The biological activity of natural compounds is also being studied. This book includes the 14 manuscripts which covered almost all aspects of PIBOC research activity in the fields of bioorganic chemistry, biochemistry, organic synthesis of natural compounds, marine microbiology, and genetic engineering, and we hope it will provide interesting new information for scientists working in these fields.

polyhydroxylated steroids --- NMR spectra --- starfish --- Anthenoides laevigatus --- cytotoxicity --- soft agar assay --- kainic acid --- domoic acid --- dysiherbaine --- neodysiherbaine A --- marine bacteria --- whole genome sequence --- porin --- amino acids composition --- bilayer lipid membrane --- pore-forming activity --- spatial structure --- phlorotannins --- phlorethols --- anticancer activity --- colorectal cancer --- radiosensitizer --- radiotherapy --- 1,4-naphthoquinones --- quinoid compounds --- thioglycosides --- quinone-sugar conjugates --- cytotoxic activity --- antibiotic activity --- histochrome --- echinochrome A --- oxidative degradation --- HPLC–DAD–MS --- NMR --- actinoporin --- sea anemone --- Heteractis crispa --- anti-migratory activity --- glycosphingolipids --- cerebrosides --- peroxidation products --- structure elucidation --- allylic thioether --- ESI-MS --- GC-MS --- mass spectra --- glass sponge --- isomalabaricanes --- Stelletta sp. --- marine sponge --- terpenoid --- Cobetia amphilecti --- Cobetia litoralis --- Cobetia pacifica --- Cobetia marina --- Cobetia crustatorum --- identification markers --- alkaline phosphatase PhoA --- lanosterol 14-alpha demethylase --- flavonoids --- enzyme inhibition --- surface plasmon resonance --- spectral titration --- molecular docking --- Zobellia --- genomes --- polysaccharide lyase family 7 --- alginate utilization system --- paralogs --- orthologs --- recombinant phospholipase A1 --- Yersinia pseudotuberculosis --- inclusion bodies --- fusion protein --- green fluorescent protein --- porin gene expression --- antibiotic stress --- phenotypic heterogeneity --- n/a --- HPLC-DAD-MS

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The G.B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far-Eastern Branch of the Russian Academy of Sciences (PIBOC FEB RAS) was founded in 1964 in Vladivostok in the Far East of Russia. Over many years, we have been carrying out studies on the natural products of both marine and terrestrial origin. In collaboration with many Russian and foreign scientists, we have investigated many hundreds of diverse biomolecules, including steroids and terpenoids, quinoid compounds and alkaloids, polysaccharides and lipids, enzymes and lectins, proteins, and peptides. The Institute has a collection of marine microorganisms (KMM) PIBOC, which includes more than 4000 strains of marine bacteria and more than 1000 strains of marine fungi. The biological activity of natural compounds is also being studied. This book includes the 14 manuscripts which covered almost all aspects of PIBOC research activity in the fields of bioorganic chemistry, biochemistry, organic synthesis of natural compounds, marine microbiology, and genetic engineering, and we hope it will provide interesting new information for scientists working in these fields.

Research & information: general --- polyhydroxylated steroids --- NMR spectra --- starfish --- Anthenoides laevigatus --- cytotoxicity --- soft agar assay --- kainic acid --- domoic acid --- dysiherbaine --- neodysiherbaine A --- marine bacteria --- whole genome sequence --- porin --- amino acids composition --- bilayer lipid membrane --- pore-forming activity --- spatial structure --- phlorotannins --- phlorethols --- anticancer activity --- colorectal cancer --- radiosensitizer --- radiotherapy --- 1,4-naphthoquinones --- quinoid compounds --- thioglycosides --- quinone-sugar conjugates --- cytotoxic activity --- antibiotic activity --- histochrome --- echinochrome A --- oxidative degradation --- HPLC-DAD-MS --- NMR --- actinoporin --- sea anemone --- Heteractis crispa --- anti-migratory activity --- glycosphingolipids --- cerebrosides --- peroxidation products --- structure elucidation --- allylic thioether --- ESI-MS --- GC-MS --- mass spectra --- glass sponge --- isomalabaricanes --- Stelletta sp. --- marine sponge --- terpenoid --- Cobetia amphilecti --- Cobetia litoralis --- Cobetia pacifica --- Cobetia marina --- Cobetia crustatorum --- identification markers --- alkaline phosphatase PhoA --- lanosterol 14-alpha demethylase --- flavonoids --- enzyme inhibition --- surface plasmon resonance --- spectral titration --- molecular docking --- Zobellia --- genomes --- polysaccharide lyase family 7 --- alginate utilization system --- paralogs --- orthologs --- recombinant phospholipase A1 --- Yersinia pseudotuberculosis --- inclusion bodies --- fusion protein --- green fluorescent protein --- porin gene expression --- antibiotic stress --- phenotypic heterogeneity --- polyhydroxylated steroids --- NMR spectra --- starfish --- Anthenoides laevigatus --- cytotoxicity --- soft agar assay --- kainic acid --- domoic acid --- dysiherbaine --- neodysiherbaine A --- marine bacteria --- whole genome sequence --- porin --- amino acids composition --- bilayer lipid membrane --- pore-forming activity --- spatial structure --- phlorotannins --- phlorethols --- anticancer activity --- colorectal cancer --- radiosensitizer --- radiotherapy --- 1,4-naphthoquinones --- quinoid compounds --- thioglycosides --- quinone-sugar conjugates --- cytotoxic activity --- antibiotic activity --- histochrome --- echinochrome A --- oxidative degradation --- HPLC-DAD-MS --- NMR --- actinoporin --- sea anemone --- Heteractis crispa --- anti-migratory activity --- glycosphingolipids --- cerebrosides --- peroxidation products --- structure elucidation --- allylic thioether --- ESI-MS --- GC-MS --- mass spectra --- glass sponge --- isomalabaricanes --- Stelletta sp. --- marine sponge --- terpenoid --- Cobetia amphilecti --- Cobetia litoralis --- Cobetia pacifica --- Cobetia marina --- Cobetia crustatorum --- identification markers --- alkaline phosphatase PhoA --- lanosterol 14-alpha demethylase --- flavonoids --- enzyme inhibition --- surface plasmon resonance --- spectral titration --- molecular docking --- Zobellia --- genomes --- polysaccharide lyase family 7 --- alginate utilization system --- paralogs --- orthologs --- recombinant phospholipase A1 --- Yersinia pseudotuberculosis --- inclusion bodies --- fusion protein --- green fluorescent protein --- porin gene expression --- antibiotic stress --- phenotypic heterogeneity

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Carotenoids represent a large group of isoprenoid structures with many different structural characteristics and biological activities. They are the most important of the naturally occurring pigments and are responsible for the various colors of different fruits, vegetables, and plant parts. Marine carotenoids and their unique structures are responsible for the color of many fish, shellfish, and algae. However, while there have been many papers and reviews on carotenoids of terrestrial origin, there has been relatively little research conducted on the impact of marine carotenoids on human health. Recent research efforts have revealed that marine carotenoids have strong biological activity affecting human health and are candidates for nutraceuticals. This Topical Collection of Marine Drugs is dedicated to marine carotenoids, and will focus on the benefits of carotenoids for human beings. For a better understanding of the physiological effects of marine carotenoids, this collection should include the most recent developments in the presence, analysis, chemistry, and biochemistry of marine carotenoids.

fucoxanthin --- scopolamine --- acetylcholinesterase --- Alzheimer’s disease --- cognitive impairments --- mytiloxanthin --- anti-oxidative activity --- singlet oxygen --- hydroxyl radical --- lipid peroxidation --- astaxanthin production --- carotenoids --- genome-reduced Corynebacterium glutamicum --- systematic approach --- metabolic engineering --- marine microalgae --- seaweeds --- nonconventional extraction --- electrotechnologies --- pulsed electric field-assisted extraction --- supercritical fluid extraction --- green processing --- microwave-assisted extraction --- marine drugs --- Bangia fuscopurpurea --- red algae --- lycopene cyclase --- carotenoid --- metabolism --- astaxanthin --- Escherichia coli --- β-carotene ketolase --- β-carotene hydroxylase --- Haematococcus pluvialis --- PII signaling protein --- nitrogen starvation --- gene cloning --- mRNA expression --- microalgae --- anti-angiogenic --- cardioprotective activity --- anti-cancer --- anti-diabetic --- anti-inflammatory --- anti-obesity --- anti-oxidant --- beauty --- Phaeodactylum tricornutum --- spectrophotometry --- high through-put screening --- antioxidants --- bioactive compounds --- blue biotechnology --- marine microorganisms --- ozonolysis --- apo-fucoxanthinone --- Caco-2 --- antiproliferative effect --- Pyropia yezoensis --- α-cryptoxanthin --- zeinoxanthin --- lutein-5,6-epoxide --- antheraxanthin --- carotenoid synthesis pathway --- red seaweed --- human papillomavirus 16 (HPV16) --- astaxanthin (Asta) --- acrosome reaction --- cholera toxin subunit B (CTB) --- L1 protein --- cigarette smoke exposure --- p38 MAPK --- antioxidant inflammatory --- synaptic-associated plasticity --- comparative transcriptome analyses --- alcoholic liver disease --- bioinformatic analysis --- phytoene --- fluridone --- cosmeceuticals --- anti-obesity effect --- Phaeodactylum extract --- Coelastrum --- canthaxanthin --- lutein --- nanoemulsion --- sublingual delivery --- ascorbyl palmitate --- Franz cell --- alcoholic liver injury --- oxidative stress --- Nrf2 --- TLR4 --- chronic obstructive pulmonary disease --- nuclear factor erythroid 2-related factor 2 --- heme oxygenase-1 --- siphonaxanthin --- dehydro-metabolite --- white adipose tissue --- metabolic pathway in vivo --- stereochemistry --- Tigriopus --- copepod --- meso-zeaxanthin --- zeaxanthin --- reactive oxygen species --- immune system --- antioxidant --- antibiotics --- thermal stress --- disease --- halocynthiaxanthin --- intestinal absorption --- functional food --- apoptosis --- inflammation --- lipid metabolism --- high-fat diet