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Fibroblast growth factor 23
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ISBN: 0128180374 0128180366 9780128180372 9780128180365 Year: 2021 Publisher: Waltham, Massachusetts : Elsevier,

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Fucoidans
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Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Fucoidans are a group of fucose-containing sulfated polysaccharides found in many species of brown seaweeds, with numerous bioactive properties. As a highly bioactive seaweed substance with many promising physiological activities, fucoidans have attracted attention from many industries all over the world. Even though fucoidans are a rich source of bioactive properties, the structural properties and bioactive mechanisms of fucoidans are poorly understood. Therefore, novel studies that either characterize the physical properties or biological activities of fucoidans will fill the knowledge gap between industrial applications and the scientific background of those applications. Both purified and partially purified fucoidans isolated from brown seaweeds present high potential as preventative and therapeutic agents against number of chronic diseases, due to their anti-inflammatory, antioxidant, anticancer, neuroprotective, antiviral, antimicrobial, and anticoagulative properties. This Special Issue is aimed at presenting updated information on well-documented studies of the structural characterization and major biological actions relevant for medical, cosmeceutical, and pharmaceutical applications that fucoidans isolated from brown seaweed can offer.


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Clinical Research on Diabetic Complications
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Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Refrigeration, air conditioning, and heat pumps (RACHP) have an important impact on the final energy uses of many sectors of modern society, such as residential, commercial, industrial, transport, and automotive. Moreover, RACHP also have an important environmental impact due to the working fluids that deplete the stratospheric ozone layer, which are being phased out according to the Montreal Protocol (1989). Last, but not least, high global working potential (GWP), working fluids (directly), and energy consumption (indirectly) are responsible for a non-negligible quota of greenhouse gas (GHG) emissions in the atmosphere, thus impacting climate change.

Keywords

History of engineering & technology --- burnt-out diabetes --- chronic kidney disease (CKD) --- dialysis --- end-stage renal disease (ESRD) --- incident diabetes mellitus (DM) --- insulin resistance --- dementia --- dipeptidyl-peptidase IV inhibitors --- diabetes mellitus --- type 2 --- Alzheimer’s disease --- vascular --- diabetes --- microperimetry --- type 2 diabetes mellitus --- glucose fluctuations --- sarcopenia --- diabetic retinopathy --- type 1 diabetes --- quality of life --- treatment satisfaction --- patient-reported outcomes --- plaque characteristics --- carotid plaque --- echogenic plaque --- diabetic foot syndrome --- vascular disease --- fibroblast growth factor 23 --- Klotho --- inflammation --- dermal electrochemical conductance --- neuropathy --- primary care --- screening --- sudomotor reflex --- prediabetes --- arterial stiffness --- baPWV --- aspirin --- primary prevention --- meta-analysis --- trial sequential analysis --- sCD36 --- type 1 diabetes mellitus --- branched-chain amino acids --- metabolomics --- NMR spectroscopy --- diabetic kidney disease --- reno-cardiovascular protection --- sodium-glucose co-transporter 2 inhibitors --- glucagon-like peptide-1 receptor agonists --- dipeptidyl peptidase 4 inhibitors --- obesity --- bariatric surgery --- diabetic macroangiopathy --- cardiovascular disease --- heart disease --- cerebrovascular disease --- peripheral artery disease --- diabetic foot disease --- diabetic microangiopathy --- diabetic neuropathy


Book
Fucoidans
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Fucoidans are a group of fucose-containing sulfated polysaccharides found in many species of brown seaweeds, with numerous bioactive properties. As a highly bioactive seaweed substance with many promising physiological activities, fucoidans have attracted attention from many industries all over the world. Even though fucoidans are a rich source of bioactive properties, the structural properties and bioactive mechanisms of fucoidans are poorly understood. Therefore, novel studies that either characterize the physical properties or biological activities of fucoidans will fill the knowledge gap between industrial applications and the scientific background of those applications. Both purified and partially purified fucoidans isolated from brown seaweeds present high potential as preventative and therapeutic agents against number of chronic diseases, due to their anti-inflammatory, antioxidant, anticancer, neuroprotective, antiviral, antimicrobial, and anticoagulative properties. This Special Issue is aimed at presenting updated information on well-documented studies of the structural characterization and major biological actions relevant for medical, cosmeceutical, and pharmaceutical applications that fucoidans isolated from brown seaweed can offer.


Book
Clinical Research on Diabetic Complications
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Refrigeration, air conditioning, and heat pumps (RACHP) have an important impact on the final energy uses of many sectors of modern society, such as residential, commercial, industrial, transport, and automotive. Moreover, RACHP also have an important environmental impact due to the working fluids that deplete the stratospheric ozone layer, which are being phased out according to the Montreal Protocol (1989). Last, but not least, high global working potential (GWP), working fluids (directly), and energy consumption (indirectly) are responsible for a non-negligible quota of greenhouse gas (GHG) emissions in the atmosphere, thus impacting climate change.


Book
Clinical Research on Diabetic Complications
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
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Bookmark

Abstract

Refrigeration, air conditioning, and heat pumps (RACHP) have an important impact on the final energy uses of many sectors of modern society, such as residential, commercial, industrial, transport, and automotive. Moreover, RACHP also have an important environmental impact due to the working fluids that deplete the stratospheric ozone layer, which are being phased out according to the Montreal Protocol (1989). Last, but not least, high global working potential (GWP), working fluids (directly), and energy consumption (indirectly) are responsible for a non-negligible quota of greenhouse gas (GHG) emissions in the atmosphere, thus impacting climate change.

Keywords

History of engineering & technology --- burnt-out diabetes --- chronic kidney disease (CKD) --- dialysis --- end-stage renal disease (ESRD) --- incident diabetes mellitus (DM) --- insulin resistance --- dementia --- dipeptidyl-peptidase IV inhibitors --- diabetes mellitus --- type 2 --- Alzheimer’s disease --- vascular --- diabetes --- microperimetry --- type 2 diabetes mellitus --- glucose fluctuations --- sarcopenia --- diabetic retinopathy --- type 1 diabetes --- quality of life --- treatment satisfaction --- patient-reported outcomes --- plaque characteristics --- carotid plaque --- echogenic plaque --- diabetic foot syndrome --- vascular disease --- fibroblast growth factor 23 --- Klotho --- inflammation --- dermal electrochemical conductance --- neuropathy --- primary care --- screening --- sudomotor reflex --- prediabetes --- arterial stiffness --- baPWV --- aspirin --- primary prevention --- meta-analysis --- trial sequential analysis --- sCD36 --- type 1 diabetes mellitus --- branched-chain amino acids --- metabolomics --- NMR spectroscopy --- diabetic kidney disease --- reno-cardiovascular protection --- sodium-glucose co-transporter 2 inhibitors --- glucagon-like peptide-1 receptor agonists --- dipeptidyl peptidase 4 inhibitors --- obesity --- bariatric surgery --- diabetic macroangiopathy --- cardiovascular disease --- heart disease --- cerebrovascular disease --- peripheral artery disease --- diabetic foot disease --- diabetic microangiopathy --- diabetic neuropathy --- burnt-out diabetes --- chronic kidney disease (CKD) --- dialysis --- end-stage renal disease (ESRD) --- incident diabetes mellitus (DM) --- insulin resistance --- dementia --- dipeptidyl-peptidase IV inhibitors --- diabetes mellitus --- type 2 --- Alzheimer’s disease --- vascular --- diabetes --- microperimetry --- type 2 diabetes mellitus --- glucose fluctuations --- sarcopenia --- diabetic retinopathy --- type 1 diabetes --- quality of life --- treatment satisfaction --- patient-reported outcomes --- plaque characteristics --- carotid plaque --- echogenic plaque --- diabetic foot syndrome --- vascular disease --- fibroblast growth factor 23 --- Klotho --- inflammation --- dermal electrochemical conductance --- neuropathy --- primary care --- screening --- sudomotor reflex --- prediabetes --- arterial stiffness --- baPWV --- aspirin --- primary prevention --- meta-analysis --- trial sequential analysis --- sCD36 --- type 1 diabetes mellitus --- branched-chain amino acids --- metabolomics --- NMR spectroscopy --- diabetic kidney disease --- reno-cardiovascular protection --- sodium-glucose co-transporter 2 inhibitors --- glucagon-like peptide-1 receptor agonists --- dipeptidyl peptidase 4 inhibitors --- obesity --- bariatric surgery --- diabetic macroangiopathy --- cardiovascular disease --- heart disease --- cerebrovascular disease --- peripheral artery disease --- diabetic foot disease --- diabetic microangiopathy --- diabetic neuropathy


Book
Fucoidans
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

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Bookmark

Abstract

Fucoidans are a group of fucose-containing sulfated polysaccharides found in many species of brown seaweeds, with numerous bioactive properties. As a highly bioactive seaweed substance with many promising physiological activities, fucoidans have attracted attention from many industries all over the world. Even though fucoidans are a rich source of bioactive properties, the structural properties and bioactive mechanisms of fucoidans are poorly understood. Therefore, novel studies that either characterize the physical properties or biological activities of fucoidans will fill the knowledge gap between industrial applications and the scientific background of those applications. Both purified and partially purified fucoidans isolated from brown seaweeds present high potential as preventative and therapeutic agents against number of chronic diseases, due to their anti-inflammatory, antioxidant, anticancer, neuroprotective, antiviral, antimicrobial, and anticoagulative properties. This Special Issue is aimed at presenting updated information on well-documented studies of the structural characterization and major biological actions relevant for medical, cosmeceutical, and pharmaceutical applications that fucoidans isolated from brown seaweed can offer.

Keywords

Medicine --- fucoidan --- low-molecular-weight fucoidan --- adriamycin --- nephrotic syndrome --- psoriasis --- Traf3ip2 --- microbiota --- mucin --- IgA --- fucoidans --- extraction --- brown algae --- production --- bioactivities --- Sri Lankan algae --- anticancer --- sulfated polysaccharide --- Celluclast --- sargassum --- antioxidant --- Maldives --- Padina boryana --- zebrafish --- apoptosis --- DR4 --- mitochondrial pathway --- cancer --- metastasis --- epithelial mesenchymal transition --- nanoparticles --- Helicobacter pylori --- mozuku --- Cladosiphon okamuranus Tokida --- urinalysis --- fucose --- enzymatic purification --- age-related macular degeneration --- VEGF --- oxidative stress --- Laminaria digitata --- Fucus distichus subsp. evanescens --- Saccharina latissima --- retinal pigment epithelium --- ROS --- Phaeophyta --- carbohydrate --- UVB irradiation --- HaCaT cells --- sulfated heterosaccharide --- dopamine neurons apoptosis --- PI3K-Akt --- ascorbic acid --- anti-lung cancer --- human lung carcinoma A-549 cells --- hydrogen peroxide --- Sargassum crassifolium --- fucoidan from Ascophyllum nodosum --- postprandial hyperglycemia --- in vitro and in vivo evaluation --- SGLT1 --- chitosan --- fibroblast growth factor-2 --- polyelectrolyte multilayer --- infrared spectroscopy --- quartz crystal microbalance --- sulfated polysaccharides --- natural defenses --- phenolic metabolism --- phenylalanine ammonia-lyase --- fucoidan --- low-molecular-weight fucoidan --- adriamycin --- nephrotic syndrome --- psoriasis --- Traf3ip2 --- microbiota --- mucin --- IgA --- fucoidans --- extraction --- brown algae --- production --- bioactivities --- Sri Lankan algae --- anticancer --- sulfated polysaccharide --- Celluclast --- sargassum --- antioxidant --- Maldives --- Padina boryana --- zebrafish --- apoptosis --- DR4 --- mitochondrial pathway --- cancer --- metastasis --- epithelial mesenchymal transition --- nanoparticles --- Helicobacter pylori --- mozuku --- Cladosiphon okamuranus Tokida --- urinalysis --- fucose --- enzymatic purification --- age-related macular degeneration --- VEGF --- oxidative stress --- Laminaria digitata --- Fucus distichus subsp. evanescens --- Saccharina latissima --- retinal pigment epithelium --- ROS --- Phaeophyta --- carbohydrate --- UVB irradiation --- HaCaT cells --- sulfated heterosaccharide --- dopamine neurons apoptosis --- PI3K-Akt --- ascorbic acid --- anti-lung cancer --- human lung carcinoma A-549 cells --- hydrogen peroxide --- Sargassum crassifolium --- fucoidan from Ascophyllum nodosum --- postprandial hyperglycemia --- in vitro and in vivo evaluation --- SGLT1 --- chitosan --- fibroblast growth factor-2 --- polyelectrolyte multilayer --- infrared spectroscopy --- quartz crystal microbalance --- sulfated polysaccharides --- natural defenses --- phenolic metabolism --- phenylalanine ammonia-lyase


Book
Clinical Studies, Big Data, and Artificial Intelligence in Nephrology and Transplantation
Authors: --- ---
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

In recent years, artificial intelligence has increasingly been playing an essential role in diverse areas in medicine, assisting clinicians in patient management. In nephrology and transplantation, artificial intelligence can be utilized to enhance clinical care, such as through hemodialysis prescriptions and the follow-up of kidney transplant patients. Furthermore, there are rapidly expanding applications and validations of comprehensive, computerized medical records and related databases, including national registries, health insurance, and drug prescriptions. For this Special Issue, we made a call to action to stimulate researchers and clinicians to submit their invaluable works and present, here, a collection of articles covering original clinical research (single- or multi-center), database studies from registries, meta-analyses, and artificial intelligence research in nephrology including acute kidney injury, electrolytes and acid–base, chronic kidney disease, glomerular disease, dialysis, and transplantation that will provide additional knowledge and skills in the field of nephrology and transplantation toward improving patient outcomes.

Keywords

Medicine --- tacrolimus --- C/D ratio --- tacrolimus metabolism --- everolimus --- conversion --- kidney transplantation --- gut microbiome --- renal transplant recipient --- diarrhea --- immunosuppressive medication --- gut microbiota --- 16S rRNA sequencing --- butyrate-producing bacteria --- Proteobacteria --- torquetenovirus --- immunosuppression --- transplantation --- immunosuppressed host --- outcome --- renal transplantation --- Goodpasture syndrome --- anti-GBM disease --- epidemiology --- hospitalization --- outcomes --- acute kidney injury --- risk prediction --- artificial intelligence --- patent ductus arteriosus --- conservative management --- blood pressure --- eradication --- interferon-free regimen --- hepatitis C infection --- kidney transplant --- allograft steatosis --- lipopeliosis --- transplant numbers --- live donors --- public awareness --- Google TrendsTM --- machine learning --- big data --- nephrology --- chronic kidney disease --- NLR --- PLR --- RPGN --- predictive value --- hemodialysis --- withdrawal --- cellular crescent --- global sclerosis --- procurement kidney biopsy --- glomerulosclerosis --- minimally-invasive donor nephrectomy --- robot-assisted surgery --- laparoscopic surgery --- organ donation --- living kidney donation --- MeltDose® --- LCPT --- renal function --- liver transplantation --- metabolism --- erythropoietin --- fibroblast growth factor 23 --- death --- weekend effect --- in-hospital mortality --- comorbidity --- dialysis --- elderly --- klotho --- α-Klotho --- FGF-23 --- kidney donor --- Nephrology --- CKD-MBD --- CKD-Mineral and Bone Disorder --- deceased donor --- Eurotransplant Senior Program --- risk stratification --- intensive care --- kidney transplant recipients --- long-term outcomes --- graft failure --- cardiovascular mortality --- lifestyle --- inflammation --- vascular calcification --- bone mineral density --- dual-energy X-ray absorptiometry --- living donation --- repeated kidney transplantation --- graft survival --- prolonged ischaemic time --- patient survival --- pre-emptive transplantation --- metabolomics --- urine --- acute rejection --- allograft --- cystatin C --- hyperfiltration --- kidney injury molecule (KIM)-1 --- tubular damage --- genetic polymorphisms --- (cardiac) surgery --- inflammatory cytokines --- clinical studies --- chronic kidney disease (CKD) --- no known kidney disease (NKD) --- ICD-10 billing codes --- phenotyping --- electronic health record (EHR) --- estimated glomerular filtration rate (eGFR) --- machine learning (ML) --- generalized linear model network (GLMnet) --- random forest (RF) --- artificial neural network (ANN), clinical natural language processing (clinical NLP) --- discharge summaries --- laboratory values --- area under the receiver operating characteristic (AUROC) --- area under the precision-recall curve (AUCPR) --- fibrosis --- extracellular matrix --- collagen type VI --- living-donor kidney transplantation --- ethnic disparity --- tacrolimus --- C/D ratio --- tacrolimus metabolism --- everolimus --- conversion --- kidney transplantation --- gut microbiome --- renal transplant recipient --- diarrhea --- immunosuppressive medication --- gut microbiota --- 16S rRNA sequencing --- butyrate-producing bacteria --- Proteobacteria --- torquetenovirus --- immunosuppression --- transplantation --- immunosuppressed host --- outcome --- renal transplantation --- Goodpasture syndrome --- anti-GBM disease --- epidemiology --- hospitalization --- outcomes --- acute kidney injury --- risk prediction --- artificial intelligence --- patent ductus arteriosus --- conservative management --- blood pressure --- eradication --- interferon-free regimen --- hepatitis C infection --- kidney transplant --- allograft steatosis --- lipopeliosis --- transplant numbers --- live donors --- public awareness --- Google TrendsTM --- machine learning --- big data --- nephrology --- chronic kidney disease --- NLR --- PLR --- RPGN --- predictive value --- hemodialysis --- withdrawal --- cellular crescent --- global sclerosis --- procurement kidney biopsy --- glomerulosclerosis --- minimally-invasive donor nephrectomy --- robot-assisted surgery --- laparoscopic surgery --- organ donation --- living kidney donation --- MeltDose® --- LCPT --- renal function --- liver transplantation --- metabolism --- erythropoietin --- fibroblast growth factor 23 --- death --- weekend effect --- in-hospital mortality --- comorbidity --- dialysis --- elderly --- klotho --- α-Klotho --- FGF-23 --- kidney donor --- Nephrology --- CKD-MBD --- CKD-Mineral and Bone Disorder --- deceased donor --- Eurotransplant Senior Program --- risk stratification --- intensive care --- kidney transplant recipients --- long-term outcomes --- graft failure --- cardiovascular mortality --- lifestyle --- inflammation --- vascular calcification --- bone mineral density --- dual-energy X-ray absorptiometry --- living donation --- repeated kidney transplantation --- graft survival --- prolonged ischaemic time --- patient survival --- pre-emptive transplantation --- metabolomics --- urine --- acute rejection --- allograft --- cystatin C --- hyperfiltration --- kidney injury molecule (KIM)-1 --- tubular damage --- genetic polymorphisms --- (cardiac) surgery --- inflammatory cytokines --- clinical studies --- chronic kidney disease (CKD) --- no known kidney disease (NKD) --- ICD-10 billing codes --- phenotyping --- electronic health record (EHR) --- estimated glomerular filtration rate (eGFR) --- machine learning (ML) --- generalized linear model network (GLMnet) --- random forest (RF) --- artificial neural network (ANN), clinical natural language processing (clinical NLP) --- discharge summaries --- laboratory values --- area under the receiver operating characteristic (AUROC) --- area under the precision-recall curve (AUCPR) --- fibrosis --- extracellular matrix --- collagen type VI --- living-donor kidney transplantation --- ethnic disparity


Book
Clinical Studies, Big Data, and Artificial Intelligence in Nephrology and Transplantation
Authors: --- ---
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

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Bookmark

Abstract

In recent years, artificial intelligence has increasingly been playing an essential role in diverse areas in medicine, assisting clinicians in patient management. In nephrology and transplantation, artificial intelligence can be utilized to enhance clinical care, such as through hemodialysis prescriptions and the follow-up of kidney transplant patients. Furthermore, there are rapidly expanding applications and validations of comprehensive, computerized medical records and related databases, including national registries, health insurance, and drug prescriptions. For this Special Issue, we made a call to action to stimulate researchers and clinicians to submit their invaluable works and present, here, a collection of articles covering original clinical research (single- or multi-center), database studies from registries, meta-analyses, and artificial intelligence research in nephrology including acute kidney injury, electrolytes and acid–base, chronic kidney disease, glomerular disease, dialysis, and transplantation that will provide additional knowledge and skills in the field of nephrology and transplantation toward improving patient outcomes.

Keywords

tacrolimus --- C/D ratio --- tacrolimus metabolism --- everolimus --- conversion --- kidney transplantation --- gut microbiome --- renal transplant recipient --- diarrhea --- immunosuppressive medication --- gut microbiota --- 16S rRNA sequencing --- butyrate-producing bacteria --- Proteobacteria --- torquetenovirus --- immunosuppression --- transplantation --- immunosuppressed host --- outcome --- renal transplantation --- Goodpasture syndrome --- anti-GBM disease --- epidemiology --- hospitalization --- outcomes --- acute kidney injury --- risk prediction --- artificial intelligence --- patent ductus arteriosus --- conservative management --- blood pressure --- eradication --- interferon-free regimen --- hepatitis C infection --- kidney transplant --- allograft steatosis --- lipopeliosis --- transplant numbers --- live donors --- public awareness --- Google TrendsTM --- machine learning --- big data --- nephrology --- chronic kidney disease --- NLR --- PLR --- RPGN --- predictive value --- hemodialysis --- withdrawal --- cellular crescent --- global sclerosis --- procurement kidney biopsy --- glomerulosclerosis --- minimally-invasive donor nephrectomy --- robot-assisted surgery --- laparoscopic surgery --- organ donation --- living kidney donation --- MeltDose® --- LCPT --- renal function --- liver transplantation --- metabolism --- erythropoietin --- fibroblast growth factor 23 --- death --- weekend effect --- in-hospital mortality --- comorbidity --- dialysis --- elderly --- klotho --- α-Klotho --- FGF-23 --- kidney donor --- Nephrology --- CKD-MBD --- CKD-Mineral and Bone Disorder --- deceased donor --- Eurotransplant Senior Program --- risk stratification --- intensive care --- kidney transplant recipients --- long-term outcomes --- graft failure --- cardiovascular mortality --- lifestyle --- inflammation --- vascular calcification --- bone mineral density --- dual-energy X-ray absorptiometry --- living donation --- repeated kidney transplantation --- graft survival --- prolonged ischaemic time --- patient survival --- pre-emptive transplantation --- metabolomics --- urine --- acute rejection --- allograft --- cystatin C --- hyperfiltration --- kidney injury molecule (KIM)-1 --- tubular damage --- genetic polymorphisms --- (cardiac) surgery --- inflammatory cytokines --- clinical studies --- chronic kidney disease (CKD) --- no known kidney disease (NKD) --- ICD-10 billing codes --- phenotyping --- electronic health record (EHR) --- estimated glomerular filtration rate (eGFR) --- machine learning (ML) --- generalized linear model network (GLMnet) --- random forest (RF) --- artificial neural network (ANN), clinical natural language processing (clinical NLP) --- discharge summaries --- laboratory values --- area under the receiver operating characteristic (AUROC) --- area under the precision-recall curve (AUCPR) --- fibrosis --- extracellular matrix --- collagen type VI --- living-donor kidney transplantation --- ethnic disparity

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