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"Thoroughly examines the influence of aberrant epigenetics during gametogenesis and embryogenesis, affecting parents, gametes and embryos, offspring and future generations Explores health outcomes for reproductive senescence, endocrine disruption, testicular cancer, prostrate cancer, breast cancer, ovarian, cancer, endometrial cancer and cervical cancers Features chapter contributions from international researchers in the field"--
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Epigenetics. --- Genetics
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Epigenetics --- Research. --- Genetics
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"Thoroughly examines fundamental concepts in exercise and sports epigenetics, methods for new research, and known impacts for human physiology, disease, and clinical outcomes Discusses exercise and sports epigenetics in relation to metabolism, obesity, aging, immunity, and neurological disease, concussion, and sports doping, among other topics Includes preliminary information on exercise epigenetics and covid-19 infection Features chapter contributions from international experts in the field"--
Exercise --- Epigenetics. --- Epigenomics. --- Physiological aspects. --- Epigenetics --- Epigenetic --- Epigenomic --- Genetics --- Exercise physiology --- Clinical exercise physiology --- Physiological effect
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Medical genetics. --- Epigenetics. --- Genetics, Medical. --- Epigenomics --- Epigenetics --- Epigenetic --- Epigenomic --- Medical Genetics --- Anthropology, Physical --- Chromosome Disorders --- Sex Chromosome Disorders --- Genetic Diseases, Inborn --- Molecular Medicine --- Genetics --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Genetic aspects
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Leukemia --- Epigenetics. --- Proteomics. --- Genetic aspects. --- Molecular biology --- Proteins --- Genetics --- Epigenomics. --- genetics. --- Genomics --- Epigenetics --- Epigenetic --- Epigenomic --- Leucèmia --- Epigenètica --- Proteòmica --- Biologia molecular --- Proteïnes --- Genètica --- Anèmia --- Càncer --- Leucèmia aguda --- Leucèmia en els infants --- Leucèmia mieloide
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Metabolites. --- Metabolism. --- Anabolism --- Catabolism --- Metabolism, Primary --- Primary metabolism --- Biochemistry --- Physiology --- Secondary metabolites --- Biomolecules --- Biological products --- Chemical ecology --- Epigenetics. --- Genetics
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"Epigenetic Regulation in Overcoming Chemoresistance, Volume 16, explains how epigenetic agents can enhance the chemotherapy sensitivity of diverse types of cancers. The book provides a comprehensive delineation and the recent development of the scientific studies on the epigenetic regulation in enhancing chemo-sensitivity. In addition, it discusses several topics such as DNA methyltransferase inhibitors (DNMTi), Histone deacetylases inhibitors (HDACi), Histone lysine demethylases inhibitors (HDMi), Histone lysine methyltransferases inhibitors (HMTi) and drugs regulating the microRNA, long non-coding RNA (lncRNA) or RNA methylation. Finally, recent and future developments of the field of epigenetic regulation are explored. This is a valuable resource for cancer researchers, clinicians, graduate students and several members of biomedical field who are interested in learning about epigenetic regulation methods to reverse chemo-resistance in cancers"--
Drug resistance in cancer cells. --- Epigenetics. --- Genetics --- Antitumor drug resistance --- Cancer drug resistance --- Drug resistance in cancer --- Drug resistance in tumor cells --- Cancer cells
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This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation; Know how genetic and epigenetic information layers are interconnected; Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms; Understand how misregulated epigenetic mechanisms can lead to disease.
Epigenetics. --- Genetic regulation. --- Molecular genetics. --- Genetics --- Molecular biology --- Gene expression --- Gene expression regulation --- Gene regulation --- Biosynthesis --- Cellular control mechanisms --- Molecular genetics --- Regulation --- Genetics and Genomics --- Biomedicine, general --- Cell Biology --- Human Genetics --- Epigenetics --- Biomedical Research --- Medical Genetics --- Cancer --- Chromatin --- Chromatin Dynamics --- Cellular Memory --- DNA Methylation --- Epigenetic Textbook --- Gene Regulation --- Gene Silencing --- Histone Modification --- Imprinting --- Inheritance --- Metabolism --- Nucleus --- Open Access --- Pluripotency --- Reprogramming --- RNA Mechanisms --- Transcription --- X Chromosome inactivation --- Genetics (non-medical) --- Medical research --- Cellular biology (cytology) --- Epigenètica
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This book reviews a novel and exciting field of cellular and molecular biology called epitranscriptomics, which focuses on changes in an organism’s cells resulting from the posttranscriptional modification of cellular RNA. RNA-binding proteins (RBPs) play a crucial role in these posttranscriptional modifications and also support several cellular processes necessary for maintaining RNA homeostasis. Exploring the mechanisms underlying RNA modifications and RBP function is an emerging area of biomedical research, taking the study of gene regulation a step beyond epigenetics. This book reveals that the RNA molecule is not just an information-carrying molecule with some secondary structures. Accordingly, how RNA is modified, regulated, packaged, and controlled is an important aspect. Leading experts address questions such as where the over 170 distinct posttranscriptional RNA modifications are located on the genome, what percentage of mRNAs and noncoding RNAs these modifications include, and how an RNA modification impacts a person’s biology. In closing, the book reviews the role of RNA modifications and RBPs in a variety of diseases and their pathogenesis. Addressing some of the most exciting challenges in epitranscriptomics, this book provides a valuable and engaging resource for researchers in academia and industry studying the phenomena of RNA modification.
Epigenetics. --- RNA—Metabolism. --- Biochemistry. --- Bioinformatics. --- RNA Metabolism. --- Biological Chemistry. --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Genetics --- Data processing --- Composition --- Transcripció genètica --- Epigenètica --- Genètica --- Codi genètic --- Factors de transcripció --- RNA --- Metabolism. --- Ribonucleic acid metabolism --- Genetic transcription. --- Analysis.
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