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The EASZY assay is a mechanism-based in vivo screening assay designed to detect endocrine active chemicals acting as agonist through estrogen receptors (ERs), by inducing the expression of the green fluorescent protein (GFP) driven by the cyp19a1b promoter. The EASZY assay allows for the detection of estrogenic activity of chemicals on transgenic tg(cyp19a1b:GFP) Zebrafish embryos exposed for 96 hours during the embryonic stages of development. At the end of the experiment, the fluorescence of each newly hatched eleutheroembryo is measured using fluorescence microscope. Because the skull of early developmental stages of zebrafish is transparent, GFP is observed, imaged and quantified in vivo. The intensity of fluorescence is then quantified using image analysis software.

Endocrine toxicology.

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Aging --- Endocrine aspects. --- Aged --- Endocrine Glands --- Endocrine System Diseases --- physiology

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Endocrine glands --- Endocrine Gland Neoplasms --- Cancer --- Cancer of the Endocrine Gland --- Carcinoma of Endocrine Gland --- Endocrine Gland Carcinoma --- Neoplasms, Endocrine Gland --- Cancer of Endocrine Gland --- Endocrine Cancer --- Endocrine Gland Cancer --- Cancer, Endocrine --- Cancer, Endocrine Gland --- Cancers, Endocrine --- Carcinoma, Endocrine Gland --- Endocrine Cancers --- Endocrine Gland Neoplasm --- Neoplasm, Endocrine Gland --- Ductless glands --- Gland of internal secretion --- Glands, Ductless --- Glands --- Chromaffin cells --- Hormones --- Cancer.

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Epidemiology of Endocrine Tumors brings current data and clinical research into one source for a multidisciplinary audience. The book discusses the prevalence, incidence, etiology, pathology, diagnosis and treatment of various endocrine tumors. With clear and focused writing, it is essential reading for healthcare professionals, endocrinologists, oncologists, and public health professionals. Users will be able to bridge the knowledge gap that exists in the comprehensive coverage surrounding the epidemiology of endocrine tumors. Globally, the prevalence and incidence of endocrine tumors is high. This audience needs a treatise where they can gain a broad overview of endocrine tumors with a focus on epidemiology.

Endocrine glands --- Tumors --- Epidemiology.

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Aging --- Endocrine aspects. --- Hormonal aspects of aging --- Endocrinology --- Hormonal aspects --- Aged --- Endocrine Glands --- Endocrine System Diseases --- Diseases of Endocrine System --- Endocrine Diseases --- Disease, Endocrine --- Disease, Endocrine System --- Diseases, Endocrine --- Diseases, Endocrine System --- Endocrine Disease --- Endocrine System Disease --- System Disease, Endocrine --- System Diseases, Endocrine --- Elderly --- Geriatrics --- Longevity --- Aging, Biological --- Biological Aging --- Senescence --- Mutation Accumulation --- physiology