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Calorimeters. --- Calorimeters and calorimetry --- Caloristers --- Microcalorimeters --- Temperature measuring instruments

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It is now clearly established that some proteins or protein regions are devoid of any stable secondary and/or tertiary structure under physiological conditions, but still possess fundamental biological functions. These intrinsically disordered proteins (IDPs) or regions (IDRs) have peculiar features due to their plasticity such as the capacity to bind their biological targets with high specificity and low affinity, and the possibility of interaction with numerous partners. A correlation between intrinsic disorder and various human diseases such as cancer, diabetes, amyloidoses and neurodegenerative diseases is now evident, highlighting the great importance of the topic. In this volume, we have collected recent high-quality research about IDPs and human diseases. We have selected nine papers which deal with a wide range of topics, from neurodegenerative disease to cancer, from IDR-mediated interactions to bioinformatics tools, all related to IDP peculiar features. Recent advances in the IDPs/IDRs issue are here presented, contributing to the progress of knowledge of the intrinsic disorder field in human disease.

Research & information: general --- Biology, life sciences --- alpha-synuclein --- NMR --- secondary structure propensity --- pre-structured motifs (PreSMos) --- intrinsically disordered protein --- ubiquitin-proteasome system --- intrinsically disordered proteins --- protein misfolding --- molecular recognition features --- cancer --- neurodegenerative diseases --- protein degradation --- EPR spectroscopy --- isothermal titration calorimetry --- protein-ligand interaction --- site-directed spin labeling --- protein structural dynamics --- WASp interacting protein --- protein-protein interactions --- actin --- cytoskeleton remodeling --- SH3 domain --- proline-rich motif --- single nucleotide variants --- interface core and rim --- human disease --- intrinsically disordered regions --- linear motifs --- gene duplications --- de novo --- evolutionary origin --- circular dichroism --- flexibility --- fluorescence --- importin --- isothermal titration calorimetry (ITC) --- molecular docking --- nuclear magnetic resonance (NMR) --- nuclear protein 1 (NPR1) --- peptide --- Methyl-CpG-binding protein 2 (MeCP2) --- Rett syndrome --- intrinsically disordered protein (IDP) --- protein stability --- protein-DNA interaction --- proteostasis --- ubiquitin independent degradation --- NADH-26S proteasome --- alpha-synuclein --- NMR --- secondary structure propensity --- pre-structured motifs (PreSMos) --- intrinsically disordered protein --- ubiquitin-proteasome system --- intrinsically disordered proteins --- protein misfolding --- molecular recognition features --- cancer --- neurodegenerative diseases --- protein degradation --- EPR spectroscopy --- isothermal titration calorimetry --- protein-ligand interaction --- site-directed spin labeling --- protein structural dynamics --- WASp interacting protein --- protein-protein interactions --- actin --- cytoskeleton remodeling --- SH3 domain --- proline-rich motif --- single nucleotide variants --- interface core and rim --- human disease --- intrinsically disordered regions --- linear motifs --- gene duplications --- de novo --- evolutionary origin --- circular dichroism --- flexibility --- fluorescence --- importin --- isothermal titration calorimetry (ITC) --- molecular docking --- nuclear magnetic resonance (NMR) --- nuclear protein 1 (NPR1) --- peptide --- Methyl-CpG-binding protein 2 (MeCP2) --- Rett syndrome --- intrinsically disordered protein (IDP) --- protein stability --- protein-DNA interaction --- proteostasis --- ubiquitin independent degradation --- NADH-26S proteasome

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The Special Issue “Recent Advancements in Metallic Glasses” presents ten original papers, considering both scientific and application issues related to metallic glasses. The papers are devoted to general consideration of the formation and defects of the glassy structure, defect evolution due to heat treatment, deformation behavior upon compression and high-pressure torsion, amorphous-crystalline transformation, hydrogenation behavior, and biomedical applications.

Information technology industries --- metallic glasses --- defects --- structural relaxation --- heat effects --- shear elasticity --- interstitialcy theory --- mechanical spectroscopy --- mixing enthalpy --- Kohlrausch-Williams-Watts equation --- structural heterogeneity --- metallic glass --- twin roll casting --- GFA --- MicroCT --- hydrogen --- indentation --- pop-in --- plasticity --- nanoglasses --- structure evolution --- properties --- bulk metallic glass --- shear band --- dislocation theory --- scanning white light interferometry --- high-pressure torsion --- severe plastic deformation --- transmitting electron microscopy --- X-ray diffraction --- differential scanning calorimetry --- free volume --- shear modulus --- composite --- amorphous alloy --- nanolaminate --- hardness --- crack resistance --- nanostructure --- HPT deformation --- metastable phases --- metallic glasses --- defects --- structural relaxation --- heat effects --- shear elasticity --- interstitialcy theory --- mechanical spectroscopy --- mixing enthalpy --- Kohlrausch-Williams-Watts equation --- structural heterogeneity --- metallic glass --- twin roll casting --- GFA --- MicroCT --- hydrogen --- indentation --- pop-in --- plasticity --- nanoglasses --- structure evolution --- properties --- bulk metallic glass --- shear band --- dislocation theory --- scanning white light interferometry --- high-pressure torsion --- severe plastic deformation --- transmitting electron microscopy --- X-ray diffraction --- differential scanning calorimetry --- free volume --- shear modulus --- composite --- amorphous alloy --- nanolaminate --- hardness --- crack resistance --- nanostructure --- HPT deformation --- metastable phases

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The demand for aluminum alloys is increasing because of their lightness, high specific strength and other attractive properties, which can exploited in improved products for a greener environment. This book gives a correlation between the processing, microstructure and properties of several aluminium alloys. Some of them are well established and used in an enormous number of applications, while others are still under development. The processing spans from casting, rapid solidification, additive manufacturing, forming, heat-treatment and welding, which can produce interesting microstructures and a useful combination of properties.

Technology: general issues --- Al alloy --- laser induced arc hybrid welding --- heat treatment --- microstructure --- wrought aluminium alloy --- homogenization annealing --- thermodynamic equilibrium --- intermetallic phases --- differential scanning calorimetry (DSC) --- characterization methods --- scalability --- mechanical properties --- aluminium alloys --- aluminium --- ageing --- quasicrystal --- transmission electron microscopy --- aluminium alloy --- SLM --- auxetic structures --- numerical analysis --- fatigue --- Al alloy 7075-T6 --- ultrasonic fatigue --- artificial pits --- pre-corrosion --- crack initiation --- 7xxx aluminum series --- early precipitation stages --- corrosion --- Al3(Sc,Zr) particles --- annihilation of positrons --- activation energy --- material flow --- asymmetric weld --- tensile strength --- VPPA --- aluminum alloy AA5083 --- rapid solidification --- melt spinning --- high-strength aluminum --- extrusion --- bimodal microstructure --- precipitations

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This Special Issue of Polymers is a collection of 11 original high-quality scientific contributions on basic and applied research in the field of wood science and technology, and provides good examples of the recent challenges related to the production and application of wood and wood-based materials. The Special Issue includes individual papers concerned with the enhancement of the performance and technological properties of wood composites, above all plywood, as well as with the ignition and combustion of wood and wood composites in monitoring and evaluating these processes on state-of-the-art equipment, and monitoring chemical changes in wood and wood adhesives and composites. The topic of the Special Issue has clearly resonated with the world’s scientific community and the responses have come from traditionally strong wood research centers in Europe and Asia.

plywood --- veneer 3D moldability --- natural fiber reinforcement --- wood–plastic composite (WPC) --- silicone --- mechanical properties --- cytotoxicity --- casting --- ageing --- veneer --- laser-cut --- additive manufacturing --- wood composite --- birch plywood --- molecular weight --- phenol-formaldehyde resin --- soft-rot --- weathering stability --- wood-based panels --- high-density fiberboards --- bio-adhesives --- ammonium lignosulfonate --- zero-formaldehyde emission --- tropical wood --- non-isothermal thermogravimetry --- deconvolution of thermogravimetry runs --- cone calorimetry testing --- heat-release rate --- OSB --- heat flux density --- ignition time --- weight loss --- meranti --- padauk --- merbau --- thermal treatment --- wood lignin --- eco-panel --- small ignition initiator --- straw --- relative burning rate --- fire properties --- spruce wood --- cellulose --- hemicelluloses --- lignin --- extractives --- time of storage --- fiber characteristics --- torrefied wood --- fuel --- combustion --- heat release rate --- n/a --- wood-plastic composite (WPC)