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Tuberculosis.

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Tuberculosis.

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"Entirely updated and revised, the 6th edition of Clinical Tuberculosis continues to provide the TB physician with a definitive and erudite account of the latest techniques in diagnosis, treatment and control of TB, including an overview of the latest guidelines from the CDC and WHO"--

Tuberculosis --- Tuberculose --- Tuberculosis.

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Tuberculosis. --- Tuberculosis --- Treatment.

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This dissertation by Clara Braian explores the innate immune responses to Mycobacterium tuberculosis, the bacterium responsible for tuberculosis (TB). It examines how innate immune cells, such as macrophages and neutrophils, respond to TB infection and how they can limit bacterial growth through mechanisms like extracellular trap formation and trained immunity. The work highlights the role of extracellular traps in capturing the bacteria and the influence of β-glucans in enhancing the immune response. The research utilizes both in vitro models and advanced tissue models to study the interactions between immune cells and the pathogen. The goal is to improve understanding of the immune response to TB and to inform potential new treatments. The intended audience includes medical researchers and healthcare professionals interested in infectious diseases and immunology.

Mycobacterium tuberculosis. --- Immune response.