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This book explores how daily and seasonal rhythmicity is generated, how these rhythms are synchronised by our environment, and how they regulate the neuroendocrine systems that impact our physiology and behaviour. The constraints of surviving in a seasonal environment have shaped human evolution and migration, have shaped our societies and cultures, and continue to influence our everyday lives, health and wellbeing. Identifying the mechanisms whereby seasonal rhythmicity is generated and regulates the brain and body is not only important for understanding the natural world and relevant to animal production, it also offers many insights into the human condition. Each chapter is written by an international expert in the field of chronobiology. A historical perspective on how research into photoperiodism and rhythmicity progressed is initially provided, but the main focus of this book is on the remarkable studies in the last few decades that have unravelled the molecular and cellular machinery underpinning circadian and circannual timing. Topics covered include the role of melatonin in communicating seasonal information to the brain and pituitary gland, the neuroanatomical pathways in mammals, birds and fish by which changes in photoperiod reach the hypothalamus, the role of glial cells (tanycytes) and thyroid hormone in seasonal rhythmicity, neuroplasticity across seasons, effects of changing day length on mood, regulation of “clock“ gene expression, and the role of the suprachiasmatic nucleus. This book will appeal to all students and researchers who wish to learn about current and past research on daily and seasonal rhythmicity. This is the tenth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. .
Neurosciences. --- Human anatomy. --- Anatomy. --- Anatomy, Human --- Anatomy --- Human biology --- Medical sciences --- Human body --- Neural sciences --- Neurological sciences --- Neuroscience --- Nervous system --- Neuroendocrinology. --- Biological rhythms. --- Biological clocks --- Biology --- Biorhythms --- Endogenous rhythms --- Living clocks --- Rhythms, Biological --- Chronobiology --- Cycles --- Pacemaker cells --- Endocrinology --- Neurology --- Neurohormones --- Periodicity
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This book presents coverage of the principles and practice of molecular clocks, which have provided fascinating and unprecedented insights into the evolutionary timescale of life on earth. It begins by following the early development of the molecular evolutionary clock in the 1960s, and leads to the complex statistical approaches that are now used to analyse genome sequences. The chapters of this book have been contributed by leading experts in the field and address the important issues of evolutionary rates, molecular dating, and phylogenomic analysis. This is the first time that these different aspects of the molecular clock have been brought together in a single, comprehensive volume. It is an invaluable reference for students and researchers interested in evolutionary biology, genetic analysis, and genomic evolution. .
Evolutionary biology. --- Bioinformatics. --- Evolutionary Biology. --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Animal evolution --- Animals --- Biological evolution --- Darwinism --- Evolutionary biology --- Evolutionary science --- Origin of species --- Evolution --- Biological fitness --- Homoplasy --- Natural selection --- Phylogeny --- Data processing --- Molecular evolution. --- Biological rhythms. --- Biological clocks --- Biorhythms --- Endogenous rhythms --- Living clocks --- Rhythms, Biological --- Chronobiology --- Cycles --- Pacemaker cells --- Biochemical evolution --- Chemical evolution --- Life --- Molecular biology --- Periodicity --- Origin
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