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Sakura est une lycéenne à la personnalité solaire, toujours entourée d'amis et au centre de l'attention de la classe. Elle est aux antipodes de Haruki, un simple élève banal et transparent. Celui-ci préfère fuir son prochain pour se réfugier dans ses livres de fiction jusqu'au jour où il trouve un journal intime, celui de Sakura. Il découvre alors que cette camarade si pleine de vie souffre d'une infection du pancréas et que ses jours sont comptés… Unis à Haruki par ce secret, Sakura demande une faveur au garçon : vivre avec elle une vie entière le temps d'un printemps…
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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
Gastrointestinal disorders --- Hepatic --- Gut --- Irritable Bowel Syndrome --- Brain-gut interactions --- Intestinal inflammation --- Liver inflammation --- Gastric cancer --- Colorectal Cancer --- Pancreatitis
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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
Science: general issues --- Pharmacology --- Gastrointestinal disorders --- Hepatic --- Gut --- Irritable Bowel Syndrome --- Brain-gut interactions --- Intestinal inflammation --- Liver inflammation --- Gastric cancer --- Colorectal Cancer --- Pancreatitis
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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
Science: general issues --- Pharmacology --- Gastrointestinal disorders --- Hepatic --- Gut --- Irritable Bowel Syndrome --- Brain-gut interactions --- Intestinal inflammation --- Liver inflammation --- Gastric cancer --- Colorectal Cancer --- Pancreatitis --- Gastrointestinal disorders --- Hepatic --- Gut --- Irritable Bowel Syndrome --- Brain-gut interactions --- Intestinal inflammation --- Liver inflammation --- Gastric cancer --- Colorectal Cancer --- Pancreatitis
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The introduction and widespread implementation of newborn bloodspot screening (NBS) for cystic fibrosis (CF) has offered earlier diagnosis and better outcomes for children with CF in many countries of the world. It represents a paradigm shift in the diagnostic pathway for these families. In contrast to a clinical diagnosis, infants are now referred for diagnostic testing after a positive NBS result. The introduction of NBS has enabled the provision of early appropriate treatment to prevent the manifestations of the disease. In the near future, early diagnosis will facilitate the prompt use of new CFTR modulator therapies that correct the basic underlying molecular defect. NBS for CF has been a global success but continues to raise questions with many varied approaches and the development of new technologies, in particular the ability to undertake extensive gene examination. Which is the best protocol to achieve high sensitivity and specificity, and how to evaluate and manage infants with inconclusive diagnosis are all subjects of ongoing discussion. It is also open to question: what is the best approach to informing and counselling the parents about a positive or inconclusive NBS result? These questions are not easy to answer and require a balanced solution that reflects the local health care system and may appropriately result in different answers around the globe. The articles in this book try to answer these questions and give an overview of the current state of knowledge in NBS for CF.
Medicine --- newborn screening --- immunoreactive trypsin(ogen) --- dried blood spot --- radioimmunoassay --- DNA --- cystic fibrosis --- incidence --- malnutrition --- cost --- health policy --- CF transmembrane conductance regulator-related metabolic syndrome --- CF screen positive --- inconclusive diagnosis --- DNA analysis --- next generation sequencing --- extended genetic analysis --- presumptive diagnosis --- sweat test --- parental information --- newborn bloodspot screening --- psychological impact --- biochemical screening --- pancreatitis associated protein --- immunoreactive trypsinogen --- cystic fibrosis screen positive --- inconclusive diagnosis (CFSPID) --- bioethics --- newborn screen --- target disorder --- missed case --- sensitivity --- CFSPID --- immunoreactive trypsin --- meconium ileus --- diagnosis --- therapy --- prognosis --- newborn screening --- immunoreactive trypsin(ogen) --- dried blood spot --- radioimmunoassay --- DNA --- cystic fibrosis --- incidence --- malnutrition --- cost --- health policy --- CF transmembrane conductance regulator-related metabolic syndrome --- CF screen positive --- inconclusive diagnosis --- DNA analysis --- next generation sequencing --- extended genetic analysis --- presumptive diagnosis --- sweat test --- parental information --- newborn bloodspot screening --- psychological impact --- biochemical screening --- pancreatitis associated protein --- immunoreactive trypsinogen --- cystic fibrosis screen positive --- inconclusive diagnosis (CFSPID) --- bioethics --- newborn screen --- target disorder --- missed case --- sensitivity --- CFSPID --- immunoreactive trypsin --- meconium ileus --- diagnosis --- therapy --- prognosis
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This volume presents the technical and cultural state of the art of two of the riskiest, most complex and operator-dependent digestive operative techniques: endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasonography (EUS). The authors compare old and new techniques, shedding light on the most recent and innovative scientific findings, including those in the field of anatomic pathology and molecular biology considered relevant for the analysis of tissue samples collected during EUS. In view of the technical difficulties specific to these techniques, the book also offers access to online-videos and numerous images, making it a valuable resource both for physicians approaching these techniques for the first time as well as for those already using them. Organized into 7 sections, it describes in detail all techniques related to ERCP/EUS, together with any specific technical equipment required. It also presents a new paradigm based on the latest results in the areas of prevention, diagnosis and management of the most common complications. Clinical outcomes presented in international literature, as well as algorithms – both based on scientific evidence and expert findings – are illustrated and compared to alternative treatments.
Abdomen --- Surgery. --- Abdominal surgery --- Laparotomy --- Abdominal surgery. --- Gastroenterology . --- Interventional radiology . --- Pediatric surgery. --- Hepatology. --- Abdominal Surgery. --- Gastroenterology. --- Interventional Radiology. --- Pediatric Surgery. --- Gastroenterology --- Pediatric surgery --- Surgery, Pediatric --- Children --- Radiology, Interventional --- Medical radiology --- Therapeutics --- Internal medicine --- Digestive organs --- Diseases --- Treatment --- Malalties del pàncrees --- Cirurgia endoscòpica --- Fibrosi quística --- Hipoglucèmia --- Pancreatitis --- Cirurgia mínimament invasiva --- Endocirurgia --- Endoscòpia operativa --- Endoscòpia quirúrgica --- Endoscòpia terapèutica --- MIS (Cirurgia invasiva mínima) --- Operacions endoscòpiques --- Cirurgia operatòria --- Endoscòpia --- Microcirurgia --- Cirurgia laparoscòpica --- Càpsula endoscòpica --- Hiperinsulinèmia
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The introduction and widespread implementation of newborn bloodspot screening (NBS) for cystic fibrosis (CF) has offered earlier diagnosis and better outcomes for children with CF in many countries of the world. It represents a paradigm shift in the diagnostic pathway for these families. In contrast to a clinical diagnosis, infants are now referred for diagnostic testing after a positive NBS result. The introduction of NBS has enabled the provision of early appropriate treatment to prevent the manifestations of the disease. In the near future, early diagnosis will facilitate the prompt use of new CFTR modulator therapies that correct the basic underlying molecular defect. NBS for CF has been a global success but continues to raise questions with many varied approaches and the development of new technologies, in particular the ability to undertake extensive gene examination. Which is the best protocol to achieve high sensitivity and specificity, and how to evaluate and manage infants with inconclusive diagnosis are all subjects of ongoing discussion. It is also open to question: what is the best approach to informing and counselling the parents about a positive or inconclusive NBS result? These questions are not easy to answer and require a balanced solution that reflects the local health care system and may appropriately result in different answers around the globe. The articles in this book try to answer these questions and give an overview of the current state of knowledge in NBS for CF.
newborn screening --- immunoreactive trypsin(ogen) --- dried blood spot --- radioimmunoassay --- DNA --- cystic fibrosis --- incidence --- malnutrition --- cost --- health policy --- CF transmembrane conductance regulator-related metabolic syndrome --- CF screen positive --- inconclusive diagnosis --- DNA analysis --- next generation sequencing --- extended genetic analysis --- presumptive diagnosis --- sweat test --- parental information --- newborn bloodspot screening --- psychological impact --- biochemical screening --- pancreatitis associated protein --- immunoreactive trypsinogen --- cystic fibrosis screen positive --- inconclusive diagnosis (CFSPID) --- bioethics --- newborn screen --- target disorder --- missed case --- sensitivity --- CFSPID --- immunoreactive trypsin --- meconium ileus --- diagnosis --- therapy --- prognosis --- n/a
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