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"For many years, laboratory dogs have served as important animal models for biomedical research that has advanced human health. Conducted at the request of the U.S. Department of Veterans Affairs (VA), this report assesses whether laboratory dogs are or will continue to be necessary for biomedical research related to the VA's mission. The report concludes that using laboratory dogs in research at the VA is scientifically necessary for only a few areas of current biomedical research. The report recommends that the VA adopt an expanded set of criteria for determining when it is scientifically necessary to use laboratory dogs in VA biomedical research; that the VA promote the development and use of alternatives to laboratory dogs; and highlights opportunities for the VA to enhance the welfare of laboratory dogs that are being used in biomedical research areas for which they have been deemed necessary."--

Dogs as laboratory animals. --- Laboratory animals --- Behavior.

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"The revised fifth edition of Clinical laboratory animal medicine : an introduction" is an accessible guide to basic information for conducting animal research safely and responsibly. It includes a review of the unique anatomic and physiologic characteristics of laboratory animals, husbandry practices, and veterinary care of many animals frequently used in research, including rodents, rabbits, ferrets, zebrafish, nonhuman primates, and agricultural animals. The updated fifth edition adds two new chapters on zebrafish and large animals, new information on transgenic models and genetic editing, and expanded coverage of environmental enrichment and pain management. The book presents helpful tip boxes, images, and review questions to aid in comprehension and learning, and a companion website provides editable review questions and answers, instructional PowerPoints, additional images not found in the book, and video clips. Written for veterinary technicians, veterinary students, practicing veterinarians, and research scientists, the fifth edition of "Clinical laboratory animal medicine" continues to offer an essential guide to the ethical treatment and anatomic and physiological characteristics of research animals"-- Provided by publisher

Laboratory animals - Diseases --- Veterinary medicine --- Laboratory animals --- Animals, Laboratory. --- Animal Diseases. --- Laboratory Animal Science. --- Animaux de laboratoire --- Science des animaux de laboratoire --- Maladies.

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The zebrafish (Danio rerio) is one of the best animal models to understand biological mechanisms and develop new methods for treating some human diseases. In this framework, the zebrafish is a versatile animal model organism for many research fields because of its many advantages, including rapid embriyonic development, easy maintenance and transparency of its embryos. Zebrafish in Biomedical Research describes the current understanding of zebrafish as a model organism in biomedical science. Written by experts in the field, this volume discusses the potential use of zebrafish in neurological diseases such as Alzheimer's and Parkinson's, in respiratory and kidney diseases, and in developing new drugs.

Zebra danio. --- Zebrafish --- Animals, Laboratory --- Disease Models, Animal --- Biomedical Research --- Biology --- Zebra danios as laboratory animals. --- Medical toxicology --- Research. --- Zebrafish. --- Animals, Laboratory. --- Disease Models, Animal. --- Biomedical Research.

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The zebrafish (Danio rerio) is one of the best animal models to understand biological mechanisms and develop new methods for treating some human diseases. In this framework, the zebrafish is a versatile animal model organism for many research fields because of its many advantages, including rapid embriyonic development, easy maintenance and transparency of its embryos. Zebrafish in Biomedical Research describes the current understanding of zebrafish as a model organism in biomedical science. Written by experts in the field, this volume discusses the potential use of zebrafish in neurological diseases such as Alzheimer's and Parkinson's, in respiratory and kidney diseases, and in developing new drugs.

Zebra danio. --- Zebrafish --- Animals, Laboratory --- Disease Models, Animal --- Biomedical Research --- Experimental Medicine --- Investigational Medicine --- Investigative Medicine --- Research, Biomedical --- Research, Medical --- Medical Research --- Medicine, Experimental --- Medicine, Investigational --- Medicine, Investigative --- Animal Disease Model --- Animal Disease Models --- Disease Model, Animal --- Models, Biological --- Laboratory Animals --- Animal, Laboratory --- Laboratory Animal --- B. rerio --- D. rerio --- Zebra Fish --- Zebra Fishes --- Zebra danio --- Zebrafishes --- Brachydanio rerio --- Danio rerio --- D. rerios --- Fishes, Zebra --- Zebra danios --- danio, Zebra --- Zebrafish Proteins --- Barilius rerio --- Brachydanio frankei --- Cyprinus chapalio --- Cyprinus rerio --- Danio frankei --- Danio lineatus --- Indian danio --- Indian zebra fish --- Leopard danio --- Nuria rerio --- Perilampus striatus --- Rerio --- Striped danio --- Zebra fish (Danio) --- Zebrafish (Zebra danio) --- Danio --- Biology --- Zebra danios as laboratory animals. --- Research. --- Medical toxicology --- Laboratory animals --- Biological research --- Biomedical research

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This book provides a thorough introduction to widely used techniques for the study of the intersection between developmental biology and neuroscience, an exceptional area to address and investigate impacting biological questions. The fully updated volume examines cutting-edge techniques on a representative range of animals, including widely used genetic model systems, such as the fruit fly, zebra fish, chicken, and mouse, as well as non-canonical experimental systems opened up through the advent of genome editing. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Brain Development: Methods and Protocols, Second Edition is an ideal guide for researchers interested in utilizing recent technical advances in molecular genetics for the study of the brain.

Neurobiology. --- Developmental biology. --- Neurosciences. --- Laboratory animals. --- Developmental Biology. --- Animal Models. --- Animals, Experimental --- Animals, Laboratory --- Animals in research --- Experimental animals --- Lab animals --- Animal culture --- Laboratory organisms --- Working animals --- Animal experimentation --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Development (Biology) --- Biology --- Growth --- Ontogeny --- Neurosciences