Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Continuous pharmaceutical manufacturing is currently receiving much interest from industry and regulatory authorities, with the joint aim of allowing rapid access of novel therapeutics and existing medications to the public, without compromising high quality. Research groups from different academic institutions have significantly contributed to this field with an immense amount of published research addressing a variety of topics related to continuous processing. The book is structured to have individual chapters on the different continuous unit operations involved in drug substance and drug product manufacturing. A wide spectrum of topics are covered, including basic principles of continuous manufacturing, applications of continuous flow chemistry in drug synthesis, continuous crystallization, continuous drying, feeders and blenders, roll compaction and continuous wet granulation.The underlying theme for each of these chapters is to present to the reader the recent advances in modeling, experimental investigations and equipment design as they pertain to each individual unit operation. The book also includes chapters on quality by design (QbD) and process analytical technology (PAT) for continuous processing, process control strategies including new concepts of quality-by-control (QbC), real-time process management and plant optimization, business and supply chain considerations related to continuous manufacturing as well as safety guidelines related to continuous chemistry. A separate chapter is dedicated to discussing regulatory aspects of continuous manufacturing, with description of current regulatory environment quality/GMP aspects, as well as regulatory gaps and challenges. Our aim from publishing this book is to make it a valuable reference for readers interested in this topic, with a desire to gain a fundamental understanding of engineering principles and mechanistic studies utilized in understanding and developing continuous processes. In addition, our advanced readers and practitioners in this field will find that the technical content of Continuous Pharmaceutical Processing is at the forefront of recent technological advances, with coverage of future prospects and challenges for this technology. .

Pharmaceutical industry --- Management. --- Pharmaceutical technology. --- Pharmaceutical Sciences/Technology. --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Indústria farmacèutica --- Tecnologia farmacèutica --- Farmàcia galènica --- Tècnica farmacèutica --- Tècniques farmacèutiques --- Tecnologies farmacèutiques --- Anàlisi de medicaments --- Biotecnologia farmacèutica --- Dispositius d'administració de medicaments --- Síntesi de fàrmacs --- Sistemes d'alliberament de medicaments --- Farmàcia --- Empreses farmacèutiques --- Indústria química --- Farmàcies --- Utilització de medicaments --- Indústria cosmètica

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book consists the basic theories and comprehensive skills of surgery, plastic surgery and chin surgery. The book contains more than 1900 color surgical photos, which mainly from lip and palate surgery in “Operation Smile” and the accumulation in decades of clinical practice. It briefly introduces various surgical methods of cleft lip and palate and alternative methods, procedures and steps of recommended repair surgeries by the way of pictures and graphic. It also emphasizes on describing common and practical cleft lip and palate surgery, and explores innovative surgical methods, operative techniques and key points. By means of schematic diagrams and surgical photos, various surgical procedures for cleft lip and palate are introduced. It is a useful reference book for surgeons in plastic surgery, oral surgery, cosmetic surgery and otolaryngology.

Plastic surgery. --- Orthopedics. --- Plastic Surgery. --- Surgical Orthopedics. --- Orthopaedics --- Orthopedia --- Surgery --- Aesthetic surgery --- Cosmetic surgery --- Plastic surgery --- Reconstructive surgery --- Surgery, Aesthetic --- Surgery, Cosmetic --- Surgery, Reconstructive --- Transplantation of organs, tissues, etc. --- Plastic surgeons --- Face --- Surgery, Plastic. --- Abnormalities --- Fissura labial --- Malformacions de la boca --- Cirurgia plàstica --- Cirurgia cosmètica --- Cirurgia estètica --- Cirurgia reconstructiva --- Cirurgia reparadora --- Cirurgia --- Artroplàstia --- Cirurgia plàstica oftalmològica --- Liposucció --- Mastoplàstia --- Penjalls quirúrgics --- Pròtesis --- Rinoplàstia --- Pròtesis internes --- Anomalies de la boca --- Malalties de la boca --- Malformacions --- Fissura palatina --- Bec de llebre --- Fenedura labial --- Llavi fes --- Llavi leporí

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Skin physiology assessment is moving from a descriptive approach to a deeper understanding of biophysical and biochemical processes in the stratum corneum, such as epidermal barrier function and stratum corneum hydration. New, non-invasive approaches offer reliable and reproducible methods for product testing in the pharmaceutical and cosmetic industry, as well as in basic research. While standard instruments focus on functional aspects, innovative devices offer a deeper understanding of underlying mechanisms. This book discusses the assessment of skin physiology and of skin functions in clinical studies using non-invasive biophysical instruments, offering readers a comprehensive guide to planning, performing and evaluating the results of scientific studies in skin measurement and the legal framework for these studies. Written by leading experts in the field, it focuses on practical aspects of non-invasive measurements. After introducing the legal aspects of the current framework for clinical cosmetic studies and basic research in cosmetology, it explores the technical practicalities of organizing a testing lab and the pre-requirements for planning a study. The third and main section addresses specific topics in cosmetic testing e.g. skin hydration, and also includes chapters on sensory aspects and in vivo skin structure vizualization. This new, updated edition of Practical Aspects of Cosmetic Testing is a valuable tool for researchers, students, and medical staff wanting to gain insights into how best to assess skin functions in controlled studies using non-invasive biophysical instruments.

Dermatology. --- Allergy. --- Pharmaceutical technology. --- Human physiology. --- Allergology. --- Pharmaceutical Sciences/Technology. --- Human Physiology. --- Human biology --- Medical sciences --- Physiology --- Human body --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Allergic diseases --- Allergies --- Hypersensitivity --- Hypersensitivity, Immediate --- Immediate allergy --- Immediate hypersensitivity --- Immunologic diseases --- Immunoglobulin E --- Medicine --- Skin --- Diseases --- Cosmetics --- Testing. --- Beauty aids --- Complexion --- Make-up (Cosmetics) --- Makeup (Cosmetics) --- Costume --- Beauty, Personal --- Beauty culture --- Toilet preparations --- Pell --- Dermatologia --- Fisiologia humana. --- Tecnologia farmacèutica --- Tractaments de bellesa --- Cosmètica --- Cosmetologia --- Tractaments estètics --- Maquillatge --- Bellesa personal --- Cosmètics --- Higiene --- Farmàcia galènica --- Tècnica farmacèutica --- Tècniques farmacèutiques --- Tecnologies farmacèutiques --- Anàlisi de medicaments --- Biotecnologia farmacèutica --- Dispositius d'administració de medicaments --- Síntesi de fàrmacs --- Sistemes d'alliberament de medicaments --- Farmàcia --- Biologia humana --- Ciències de la salut --- Fisiologia --- Mecànica humana --- Reproducció humana --- Cos humà --- Medicina --- Dermatòlegs --- Dermatologia pediàtrica --- Dermatologia veterinària --- Infermeria dermatològica --- Malalties de la pell --- Cutis --- Derma --- Dermis --- Absorció (Fisiologia) --- Òrgans sensorials --- Color de la pell --- Cuir cabellut --- Dermatòglifs --- Epidermis --- Ungla --- Absorció cutània --- Cirurgia dermatològica --- Tacte --- Pell.