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Although dopaminergic medication is the most effective treatment for patients with Parkinson's disease (PD), its long-term use is associated with debilitating motor fluctuations. Patients may not spontaneously seek assistance when fluctuations develop, so strategies need to be put in place to identify and alleviate motor dysfunction. This concise resource will increase readers' awareness of: • the different types of motor fluctuation, why they occur and how to recognize them • the drugs that can be added to levodopa to reduce fluctuations • advanced and emerging therapies that will help to improve outcomes. No two patients with PD are alike in their disease progression or response to treatment. This 'Fast Facts' title provides the information healthcare professionals need to provide effective individualized care that will improve their patients' quality of life.

Geriatrics --- Neuropathology

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Quatrième de couverture : "En parfaite cohérence avec le programme de DFASM et les ECNi les ouvrages de cette collection rassemblent l'essentiel des connaissances pour chacune des spécialités sous forme de fiches synthétiques qui suivent le déroulé des Référentiels des Collèges. Présentés dans un format spiralé et une maquette agréable en bichromie ces ouvrages permettent : de se préparer à la spécialité et d'aborder les données essentielles lors d'un premier tourde réviser et retenir les connaissances acquises lors d'un dernier tour. Chaque item fait l'objet d'une fiche courte qui présente : le rappel des objectifs nationaux voire des objectifs du Collège ; des rappels anatomo-physiopathologiques si nécessaire ; des contenus synthétiques sous forme d'énumérations d'arbres diagnostiques d'algorithmes de tableaux comparatifs et récapitulatifs ; les recommandations existantes et les données incontournables ; les liens transversaux avec d'autres items. Chaque fiche se termine sur une série de questions isolées corrigées pour revenir sur les aspects incontournables de l'item et peut être complétée et personnalisée grâce à l'espace prévu à cet effet."

Geriatrics --- Internship and Residency

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Although dopaminergic medication is the most effective treatment for patients with Parkinson’s disease (PD), its long-term use is associated with debilitating motor fluctuations. Patients may not spontaneously seek assistance when fluctuations develop, so strategies need to be put in place to identify and alleviate motor dysfunction. This concise resource will increase readers’ awareness of: • the different types of motor fluctuation, why they occur and how to recognize them • the drugs that can be added to levodopa to reduce fluctuations • advanced and emerging therapies that will help to improve outcomes. No two patients with PD are alike in their disease progression or response to treatment. This 'Fast Facts' title provides the information healthcare professionals need to provide effective individualized care that will improve their patients’ quality of life.

Neurology --- Gerontology / Geriatrics

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This dissertation by Maria Edvardsson examines the circulating levels and assessment of clinical laboratory analytes in individuals aged 80 and above, categorized as 'apparently healthy', 'moderately healthy', and 'frail'. The study highlights the inadequacy of current reference intervals, which are often based on younger populations, for accurately interpreting laboratory results in the elderly. It emphasizes the need for age- and health-status-specific reference values to better understand changes in analyte levels in this demographic. The research identifies statistical differences in various analytes, such as albumin, ALT, AST, creatinine, and γ-GT, among different health statuses and suggests that elevated levels of certain biomarkers, like CRP and IL-8, may be linked to reduced survival in elderly nursing home residents. The work aims to improve clinical decision-making and treatment for older adults by advocating for personalized evaluation based on an individual's historical data.

Geriatrics. --- Health status indicators. --- Geriatrics --- Health status indicators

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Geriatrics --- Ophthalmology --- geriatrie --- oftalmologie --- gerontologie