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ISBN: 0128133341 0128133333 9780128133347 9780128133330 Year: 2019 Publisher: London, United Kingdom : Academic Press, An imprint of Elsevier,
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Depression, Mental --- Neurobiology. --- Pathophysiology. --- Depression. --- Neurosciences --- Dejection --- Depression, Unipolar --- Depressive disorder --- Depressive psychoses --- Melancholia --- Mental depression --- Unipolar depression --- Affective disorders --- Neurasthenia --- Neuroses --- Manic-depressive illness --- Melancholy --- Sadness --- Neurobiology, Cellular --- Neurobiology, Molecular --- Cellular Neurobiology --- Molecular Neurobiology --- Emotional Depression --- Depressive Symptoms --- Depression, Emotional --- Depressions --- Depressions, Emotional --- Depressive Symptom --- Emotional Depressions --- Symptom, Depressive --- Symptoms, Depressive --- Bipolar disorder
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ISBN: 9780128133347 0128133341 Year: 2019 Publisher: London, United Kingdom ;San Diego, CA Academic Press, an imprint of Elsevier
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Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness.
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