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This authoritative handbook, with its clear, concise descriptions of the important features of many common infectious diseases, will serve as a valuable guide for medical students and physicians in general paediatric practice. The authors' aim throughout has been to provide details of the usual clinical picture, the management, and the preventive or control measures widely accepted in these common infections. Tey have emphasized differential diagnosis, comparing the principal infectious diseases, particularly those with a specific rash, to other diseases with similar features, in an effort to clarify some of the essential differential diagnostic points in these diseases. Dr. Anglin and Dr. Shusterman have collaborated with Dr. Silverthorne in preparing this revision, which contains important new sections on virus infections and on ocular diseases. When the first edition of this book was published in 1958, Acta Paediatrica wrote: 'Dr. Silverthorne...has intended this concise but complete volume for the use of medical students and general practitioners. Compact in its format, and easily read, it will make a useful and valuable addition to any medical library....Particular mention should be made of the section dealing with infections in the newborn period. This rather large area is admirably well condensed, and the important points in diagnosis and management are forcefully brought out. Although not intended as a textbook it should prove exceedingly useful as a guide to the physician who daily sees the conditions which comprise its contents."

Children --- Communicable diseases. --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Diseases --- Infection --- Epidemics --- Childhood diseases --- Children's diseases --- Diseases of children --- Juvenile diseases --- Pediatrics --- Diseases.

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The vector-borne Zika virus joins avian influenza, Ebola, and yellow fever as recent public health crises threatening pandemicity. By a combination of stochastic modeling and economic geography, this book proposes two key causes together explain the explosive spread of the worst of the vector-borne outbreaks. Ecosystems in which such pathogens are largely controlled by environmental stochasticity are being drastically streamlined by both agribusiness-led deforestation and deficits in public health and environmental sanitation. Consequently, a subset of infections that once burned out relatively quickly in local forests are now propagating across susceptible human populations whose vulnerability to infection is often exacerbated in structurally adjusted cities. The resulting outbreaks are characterized by greater global extent, duration, and momentum. As infectious diseases in an age of nation states and global health programs cannot, as much of the present modeling literature presumes, be described by interacting populations of host, vector, and pathogen alone, a series of control theory models is also introduced here. These models, useful to researchers and health officials alike, explicitly address interactions between government ministries and the pathogens they aim to control.

Communicable diseases. --- Medicine. --- Public health. --- Epidemiology. --- Medicine & Public Health. --- Public Health. --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Diseases --- Infection --- Epidemics --- Public health --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation

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The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”. This volume, “Mechanisms and Models of Drug Interactions,” delivers a text that enhances clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The book provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development.

Drug interactions. --- Communicable diseases. --- Medicine. --- Pharmacy. --- Pharmaceutical technology. --- Infectious diseases. --- Biomedicine. --- Pharmaceutical Sciences/Technology. --- Infectious Diseases. --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Chemistry --- Medicine --- Drugs --- Materia medica --- Pharmacology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Diseases --- Infection --- Epidemics --- Interactions, Drug --- Side effects --- Emerging infectious diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases

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This book introduces readers to the concept of 'frugal innovation' and describes novel low-cost technologies that aid in diagnosing infectious diseases. Rapidly deployable, portable, and affordable diagnostic tools have the potential to tremendously benefit populations in resource-limited settings and improve global health outcomes. Specifically, the book includes the following features: Cutting-Edge Research: Thorough coverage of scientific advances related to frugal bioengineering that have been developed within the last few years. A few examples of technologies covered in detail include low-cost paper-based and CD-based microfluidic diagnostic systems. Industry and Non-Profit Voices: Chapters written by scientists currently working in industry and philanthropic sectors. .

Biomedical engineering. --- Communicable diseases --- Epidemiology --- Technological innovations. --- Medicine. --- Health promotion. --- Infectious diseases. --- Medicine & Public Health. --- Infectious Diseases. --- Biomedical Engineering. --- Health Promotion and Disease Prevention. --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Diseases --- Infection --- Epidemics --- Emerging infectious diseases. --- Biomedical Engineering and Bioengineering. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Health Workforce --- Health promotion programs --- Health promotion services --- Promotion of health --- Wellness programs --- Preventive health services --- Health education

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This book reviews the current strategies and challenges for the treatment of bacterial, fungal, parasitic and viral infectious diseases in developing countries. Contributing authors present expert analysis on the transmission, epidemiology, bacteriology, pathogenesis and treatment of Neglected Tropical Bacterial Diseases such as Leprosy, Buruli ulcer, and Trachoma. Particular attention is also given to current antifungal agents, their spectrum of activity, mode of action, limitations, and current challenges in antifungal therapy. The authors explore the medicinal chemistry efforts that gave rise to currently launched drugs and new anti-HIV agents, and they also highlight the latest vaccine and drug developments in the clinical management of the Ebola Virus Disease, ignited by the 2014-2016 outbreak. This work has an interdisciplinary appeal and will engage scholars and professionals in the burden of communicable diseases.

Communicable diseases. --- Communicable diseases --- Chemistry. --- Pharmaceutical technology. --- Medicinal chemistry. --- Tropical medicine. --- Medicinal Chemistry. --- Pharmaceutical Sciences/Technology. --- Tropical Medicine. --- Diseases, Tropical --- Hygiene, Tropical --- Medicine --- Public health, Tropical --- Sanitation, Tropical --- Tropical diseases --- Medical climatology --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Physical sciences --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Diseases --- Infection --- Epidemics --- Biochemistry. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Medical sciences --- Composition