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This academic thesis by Zaheer Ali investigates the mechanisms of angiogenesis, the growth of blood vessels from preexisting vasculature, using zebrafish models. The research focuses on both developmental and pathological angiogenesis, particularly in the context of age-related macular degeneration (AMD), corneal angiogenesis, melanoma, and ischemic diseases. Key findings include the identification of choroidal neovascularization mechanisms, the role of VEGF and NF-kB signaling pathways in angiogenesis, and the potential therapeutic applications of biocompatible polymers for drug delivery. The work aims to enhance understanding of angiogenic processes to inform the development of more effective treatments for various diseases. The intended audience includes medical researchers, clinicians, and students in the field of medical and health sciences.

Blood-vessels. --- Zebra danios as laboratory animals. --- Blood-vessels --- Zebra danios as laboratory animals