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Annotation Device-to-device (D2D) communications have attracted a great deal of attention from researchers in recent years. It is a promising technique for offloading local traffic from cellular base stations by allowing local devices, in physical proximity, to communicate directly with each other. Furthermore, through relaying, D2D is also a promising approach to enhancing service coverage at cell edges or in black spots. However, there are many challenges to realizing the full benefits of D2D. For one, minimizing the interference between legacy cellular and D2D users operating in underlay mode is still an active research issue. With the 5th generation (5G) communication systems expected to be the main data carrier for the Internet-of-Things (IoT) paradigm, the potential role of D2D and its scalability to support massive IoT devices and their machine-centric (as opposed to human-centric) communications need to be investigated. New challenges have also arisen from new enabling technologies for D2D communications, such as non-orthogonal multiple access (NOMA) and blockchain technologies, which call for new solutions to be proposed. This edited book presents a collection of ten chapters, including one review and nine original research works on addressing many of the aforementioned challenges and beyond.

Internet of things. --- Cellular signal transduction.

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Cellular signal transduction. --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology

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All hollow organs, such as blood vessels, the gastrointestinal tract, airways, male and female reproductive systems, and the urinary bladder are primarily composed of smooth muscle. Such organs regulate flow, propulsion and mixing of luminal contents and storage by the contraction and relaxation of smooth muscle cells. Smooth muscle cells respond to numerous inputs, including pressure, shear stress, intrinsic and extrinsic innervation, hormones and other circulating molecules, as well as autocrine and paracrine factors. This book is a review of smooth muscle cell regulation in the cardiovascular, reproductive, GI, and other organ systems with emphasis on calcium and receptor signaling.

Smooth muscle --- Cellular signal transduction. --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Nonstriated muscle --- Unstriated muscle --- Muscles --- Physiology. --- Mitochondria structure and position --- local control --- calcium signals --- smooth muscle cells

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Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development and progression. Tissue microarrays and next generation sequencing technologies have assisted us to gather missing pieces of jigsaw puzzle and we now know that deregulation of spatio-temporally controlled signaling cascades play fundamental role in metastasis and resistance against wide ranging therapeutics. This book offers a balanced overview of the rapidly emerging cutting edge research in molecular oncology and good source of knowledge for established oncologists, basic and medical students and pharmaceutical industry associated R&D departments.

Cancer cells --- Growth. --- Medicine. --- Cancer research. --- Molecular biology. --- Biomedicine. --- Cancer Research. --- Molecular Medicine. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Cancer cell growth --- Oncology. --- Health Workforce --- Tumors --- Cell Transformation, Neoplastic. --- Signal Transduction. --- MicroRNAs. --- Neoplastic Cell Transformation --- Transformation, Neoplastic Cell --- Tumorigenic Transformation --- Neoplastic Transformation, Cell --- Cell Neoplastic Transformation --- Cell Neoplastic Transformations --- Cell Transformations, Neoplastic --- Neoplastic Cell Transformations --- Neoplastic Transformations, Cell --- Transformation, Cell Neoplastic --- Transformation, Tumorigenic --- Transformations, Cell Neoplastic --- Transformations, Neoplastic Cell --- Transformations, Tumorigenic --- Tumorigenic Transformations --- Cell Line, Transformed --- Micro RNA --- MicroRNA --- Primary MicroRNA --- Primary miRNA --- miRNAs --- pre-miRNA --- pri-miRNA --- RNA, Small Temporal --- Small Temporal RNA --- miRNA --- stRNA --- MicroRNA, Primary --- RNA, Micro --- Temporal RNA, Small --- miRNA, Primary --- pre miRNA --- pri miRNA --- RNA, Small Interfering --- Receptor Mediated Signal Transduction --- Signal Transduction Pathways --- Signal Transduction Systems --- Cell Signaling --- Receptor-Mediated Signal Transduction --- Signal Pathways --- Pathway, Signal --- Pathway, Signal Transduction --- Pathways, Signal --- Pathways, Signal Transduction --- Receptor-Mediated Signal Transductions --- Signal Pathway --- Signal Transduction Pathway --- Signal Transduction System --- Signal Transduction, Receptor-Mediated --- Signal Transductions --- Signal Transductions, Receptor-Mediated --- System, Signal Transduction --- Systems, Signal Transduction --- Transduction, Signal --- Transductions, Signal --- Cell Communication --- Receptor-CD3 Complex, Antigen, T-Cell --- Receptor Cross-Talk --- Feedback, Physiological --- Gasotransmitters

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This book summarizes the emerging experimental evidence on hair-cell mechanotransduction, and covers hair’s cellular structure, biophysical properties, molecular components and functions. Auditory hair cells convert sound-induced vibration into electrical signals. This biological process, mechanotransduction, is what allows us to hear and communicate in our daily lives. However, our grasp of hair-cell mechanotransduction is still far from complete. Recent advances in molecular genetics and biophysics have helped us gain deeper insights into this process, especially the molecular constituent and operation of the channel complex. This book provides a cutting-edge snapshot for all readers who are interested in or studying how auditory hair cells detect sound. .

Cellular signal transduction. --- Cells --- Neurosciences. --- Cytology. --- Mechanical properties. --- Medicine. --- Biochemistry. --- Cell biology. --- Biomedicine. --- Biochemistry, general. --- Cell Biology. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Cell biology --- Cellular biology --- Biology --- Cytologists --- Cell mechanics --- Cellular mechanics --- Biomechanics --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Composition