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High-energy charged particles represent a cutting-edge technique in radiation oncology. Protons and carbon ions are used in several centers all over the world for the treatment of different solid tumors. Typical indications are ocular malignancies, tumors of the base of the skull, hepatocellular carcinomas and various sarcomas. The physical characteristics of the charged particles (Bragg peak) allow sparing of much more normal tissues than it is possible using conventional X-rays, and for this reason all pediatric tumors are considered eligible for protontherapy. Ions heavier than protons also display special radiobiological characteristics, which make them effective against radioresistant and hypoxic tumors. On the other hand, protons and ions with high charge (Z) and energy (HZE particles) represent a major risk for human space exploration. The main late effect of radiation exposure is cancer induction, and at the moment the dose limits for astronauts are based on cancer mortality risk. The Mars Science Laboratory (MSL) measured the dose on the route to Mars and on the planet’s surface, suggesting that a human exploration missions will exceed the radiation risk limits. Notwithstanding many studies on carcinogenesis induced by protons and heavy ions, the risk uncertainty remains very high. In this research topic we aim at gathering the experiences and opinions of scientists dealing with high-energy charged particles either for cancer treatment or for space radiation protection. Clinical results with protons and heavy ions, as well as research in medical physics and pre-clinical radiobiology are reported. In addition, ground-based and spaceflight studies on the effects of space radiation are included in this book. Particularly relevant for space studies are the clinical results on normal tissue complications and second cancers. The eBook nicely demonstrates that particle therapy in oncology and protection of astronauts from space radiation share many common topics, and can learn from each other.

carbon ions --- heavy ions --- Mars --- proton therapy --- radiotherapy --- particle radiobiology --- protons --- space radiation protection --- Charged particles --- space travel

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This book highlights the problem of UV-R-induced photocarcinogenesis and its molecular mechanism. It covers different photosensitive xenobiotics (drugs, cosmetics, and environmental pollutants) and their photosensitization mechanisms under ambient UV-R exposure. It also summarizes the role of nanotechnology in skin cancer remedies. It provides a brief overview of the various novel nanocarriers for cosmeceuticals like nanoemulsions, liposomes, solid lipid nanoparticles (SLNs), dendrimers, inorganic nanoparticles, nanocrystals, etc., nanotechnology-based cosmeceutical products which are available in the market. It highlights the possible health hazards caused by nanoparticles on exposure of nano-based cosmetics and describes the recent regulatory rules applied to avoid the nanotoxicity. .

Photochemotherapy. --- Photodynamic therapy --- Chemotherapy --- Photosensitization, Biological --- Phototherapy --- Oncology. --- Environmental protection. --- Immunology. --- Nanotechnology. --- Gene expression. --- Cancer Research. --- Effects of Radiation/Radiation Protection. --- Gene Expression. --- Genes --- Genetic regulation --- Molecular technology --- Nanoscale technology --- High technology --- Immunobiology --- Life sciences --- Serology --- Environmental quality management --- Protection of environment --- Environmental sciences --- Applied ecology --- Environmental engineering --- Environmental policy --- Environmental quality --- Tumors --- Expression --- Cancer research. --- Radiation protection. --- Radiation—Safety measures. --- Cancer research --- Radiation monitoring --- Radiation protection

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This book presents the proceedings of SICC 2017, a conference devoted to promoting the dissemination of the different methodologies, techniques, theories, strategies, technologies and best practices on the prevention and mitigation of CBRNE risks. As the first scientific international conference on safety & security issues in the CBRNE field, SICC 2017 attracted contributions resulting from fruitful inter-professional collaborations between university and military experts, specialized operators, decision makers and the industry. As such, these proceedings are primarily intended for academics and professionals from public, private and military entities. It is the first trans-disciplinary collection of scientific papers from the numerous fields related to CBRNE.

Weapons of mass destruction --- CBRNEs (Weapons) --- CBRNs (Weapons) --- Chemical, biological, radiological and nuclear weapons --- Mass destruction, Weapons of --- NBC agents (Weapons) --- NBC weapons --- Nuclear, biological and chemical weapons --- WMDs (Weapons) --- Military weapons --- Safety measures. --- Data protection. --- Chemicals --- Computer security. --- Environmental protection. --- Security Science and Technology. --- Security. --- Safety in Chemistry, Dangerous Goods. --- Systems and Data Security. --- Effects of Radiation/Radiation Protection. --- Environmental quality management --- Protection of environment --- Environmental sciences --- Applied ecology --- Environmental engineering --- Environmental policy --- Environmental quality --- Computer privacy --- Computer system security --- Computer systems --- Computers --- Cyber security --- Cybersecurity --- Electronic digital computers --- Protection of computer systems --- Security of computer systems --- Data protection --- Security systems --- Hacking --- Data governance --- Data regulation --- Personal data protection --- Protection, Data --- Electronic data processing --- Protection --- Security measures --- System safety. --- Chemistry. --- Radiation protection. --- Radiation—Safety measures. --- Radiation monitoring --- Radiation protection --- Physical sciences --- Safety, System --- Safety of systems --- Systems safety --- Accidents --- Industrial safety --- Systems engineering --- Prevention

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This book gathers selected papers from the Second International Symposium on Software Reliability, Industrial Safety, Cyber Security and Physical Protection of Nuclear Power Plant, held in Chengdu, China on August 23–25, 2017. The symposium provided a platform of technical exchange and experience sharing for a broad range of experts, scholars and nuclear power practitioners.  The book reflects the state of the art and latest trends in nuclear instrumentation and control system technologies, as well as China’s growing influence in this area. It offers a valuable resource for both practitioners and academics working in the field of nuclear instrumentation, control systems and other safety-critical systems, as well as nuclear power plant managers, public officials and regulatory authorities.

Energy. --- Nuclear energy. --- Computer security. --- Physical measurements. --- Measurement. --- Quality control. --- Reliability. --- Industrial safety. --- Nuclear engineering. --- Radiation protection. --- Radiation --- Nuclear Energy. --- Nuclear Engineering. --- Measurement Science and Instrumentation. --- Quality Control, Reliability, Safety and Risk. --- Systems and Data Security. --- Effects of Radiation/Radiation Protection. --- Radiation monitoring --- Radiation protection --- Atomic power engineering --- Industrial accidents --- Industries --- Job safety --- Occupational hazards, Prevention of --- Occupational health and safety --- Occupational safety and health --- Prevention of industrial accidents --- Prevention of occupational hazards --- Safety, Industrial --- Safety engineering --- Safety measures --- Safety of workers --- Dependability --- Trustworthiness --- Measuring --- Mensuration --- Measurements, Physical --- Atomic energy --- Atomic power --- Energy, Atomic --- Energy, Nuclear --- Nuclear power --- Power, Atomic --- Power, Nuclear --- Computer privacy --- Computer system security --- Computer systems --- Computers --- Cyber security --- Cybersecurity --- Electronic digital computers --- Protection of computer systems --- Security of computer systems --- Safety measures. --- Prevention --- Protection --- Security measures --- Nuclear power plants --- Instruments --- Electronic equipment --- System safety. --- Data protection. --- Environmental protection. --- Atomic power plants --- Nuclear power stations --- Nuclear facilities --- Power-plants --- Antinuclear movement --- Nuclear energy --- Environmental quality management --- Protection of environment --- Environmental sciences --- Applied ecology --- Environmental engineering --- Environmental policy --- Environmental quality --- Data protection --- Security systems --- Hacking --- Safety, System --- Safety of systems --- Systems safety --- Accidents --- Industrial safety --- Systems engineering --- Measurement   . --- Radiation—Safety measures. --- System safety --- Conduct of life --- Factory management --- Industrial engineering --- Reliability (Engineering) --- Sampling (Statistics) --- Standardization --- Quality assurance --- Quality of products --- Mathematics --- Technology --- Metrology --- Physical measurements --- Mathematical physics --- Measurement --- Force and energy --- Nuclear physics --- Power resources --- Nuclear engineering

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This book is the first comprehensive, in-depth English language study of the animals that were left behind in the exclusion zone in the wake of the nuclear meltdown of three of the four reactors at the Fukushima Daiichi Nuclear Power Station in March 2011, triggered by the Great East Japan Earthquake of magnitude 9.0.The Japanese government designated an area of 20-kilometer radius from the nuclear power station as an exclusion zone and evacuated one hundred thousand residents, but left companion animals and livestock animals behind in the radioactive area. Consequently, about 90 percent of the animals in the exclusion zone died. This book juxtaposes policies of the Japanese government toward the animals in Fukushima with the actions of grassroots volunteer animal rescue groups that filled the void of the government. .

Animal welfare --- Animals --- Fukushima Nuclear Disaster, Japan, 2011. --- Fukushima I Nuclear Disaster, Japan, 2011 --- Fukushima II Nuclear Disaster, Japan, 2011 --- Fukushima Accident, Japan, 2011 --- Fukushima Daiichi Nuclear Disaster, Japan, 2011 --- Fukushima Daini Nuclear Disaster, Japan, 2011 --- Fukushima Disaster, Japan, 2011 --- Fukushima Nuclear Accident, Japan, 2011 --- Nuclear power plants --- Tohoku Earthquake and Tsunami, Japan, 2011 --- Radioactive pollution --- Abuse of animals --- Animal cruelty --- Animals, Cruelty to --- Animals, Protection of --- Animals, Treatment of --- Cruelty to animals --- Humane treatment of animals --- Kindness to animals --- Mistreatment of animals --- Neglect of animals --- Prevention of cruelty to animals --- Protection of animals --- Treatment of animals --- Welfare, Animal --- Effect of radioactive pollution on. --- Accidents --- Effect of pollution on --- Physiological effect --- Abuse of --- Social aspects --- Ethics. --- Social sciences-Philosophy. --- Animal welfare. --- Environmental protection. --- Social Philosophy. --- Animal Welfare/Animal Ethics. --- Effects of Radiation/Radiation Protection. --- Environmental quality management --- Protection of environment --- Environmental sciences --- Applied ecology --- Environmental engineering --- Environmental policy --- Environmental quality --- Deontology --- Ethics, Primitive --- Ethology --- Moral philosophy --- Morality --- Morals --- Philosophy, Moral --- Science, Moral --- Philosophy --- Values --- Social sciences—Philosophy. --- Radiation protection. --- Radiation—Safety measures. --- Radiation monitoring --- Radiation protection