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Heat Stability of Concentrated Milk Systems : Kinetics of the Dissociation and Aggregation in High Heated Concentrated Milk Systems
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ISBN: 9783658196967 Year: 2018 Publisher: Wiesbaden Springer Fachmedien Wiesbaden, Imprint: Springer Spektrum

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In his study, Joseph Dumpler proves a strong correlation between the dry matter content of the milk concentrate and the maximum temperature-time combinations for the heat treatment of concentrated skim milk without visible coagulation. The author also states that direct heat treatment is superior to indirect heat treatment for preservation of liquid milk concentrates or decontamination of concentrated milk before spray drying. Contents Heat Stability of Concentrated Milk  Heat-Induced Coagulation of Concentrated Milk Heated by Direct Steam Injection Dissociation and Coagulation of Caseins and Whey Proteins Modelling of Heat Stability and Heat-Induced Aggregation of Casein Micelles Mechanistic Aspects of Heat-Induced Coagulation Target Groups Lecturers and students of dairy science and technology, food science and processing Practitioners and suppliers of processing equipment in the fields of dairying, food processing, food process engineering The Author During his PhD, Joseph Dumpler was employed as a scientific officer at the Chair Food and Bioprocess Engineering at the TUM School of Life Sciences Weihenstephan of the Technical University of Munich. His research was focused on the heat stability and heat treatment of concentrated milk by direct steam injection technology.


Digital
Advancing Development of Synthetic Gene Regulators : With the Power of High-Throughput Sequencing in Chemical Biology
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ISBN: 9789811065477 Year: 2018 Publisher: Singapore Springer Singapore, Imprint: Springer

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This book focuses on an “outside the box” notion by utilizing the powerful applications of next-generation sequencing (NGS) technologies in the interface of chemistry and biology. In personalized medicine, developing small molecules targeting a specific genomic sequence is an attractive goal. N-methylpyrrole (P)–N-methylimidazole (I) polyamides (PIPs) are a class of small molecule that can bind to the DNA minor groove. First, a cost-effective NGS (ion torrent platform)-based Bind-n-Seq was developed to identify the binding specificity of PIP conjugates in a randomized DNA library. Their biological influences rely primarily on selective DNA binding affinity, so it is important to analyze their genome-wide binding preferences. However, it is demanding to enrich specifically the small-molecule-bound DNA without chemical cross-linking or covalent binding in chromatinized genomes. Herein is described a method that was developed using high-throughput sequencing to map the differential binding sites and relative enriched regions of non-cross-linked SAHA-PIPs throughout the complex human genome. SAHA-PIPs binding motifs were identified and the genome-level mapping of SAHA-PIPs-enriched regions provided evidence for the differential activation of the gene network. A method using high-throughput sequencing to map the binding sites and relative enriched regions of alkylating PIP throughout the human genome was also developed. The genome-level mapping of alkylating the PIP-enriched region and the binding sites on the human genome identifies significant genomic targets of breast cancer. It is anticipated that this pioneering low-cost, high through-put investigation at the sequence-specific level will be helpful in understanding the binding specificity of various DNA-binding small molecules, which in turn will be beneficial for the development of small-molecule-based drugs targeting a genome-level sequence. .


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Supercritical Fluid Chromatography : Volume 1

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Supercritical Fluid Chromatography (SFC) provides a timely overview of SFC application areas which were unimaginable just a decade ago. This two-volume series opens with an overview of the history and expectant future of SFC and continues with recent applications in the pharmaceutical industry and other fascinating areas of science. SFC has found its place in the pharmaceutical industry with an increasing body of applications for chiral and achiral molecules in both the research and development phases of the drug discovery process. As illustrated in this two-volume series, the current interest in SFC extends well beyond the pharmaceutical industry. Chapters encompassing applications for polar and non-polar mixtures of importance are covering widely disparate areas in substance abuse, natural products including cannabinoids, bioactive lipids, flavor and fragrance. With its broad balance and coverage, this two-volume book constitutes a unique educational platform to students and scientists for many years to come. The major objective of this book editions is to inspire and stimulate readers to continue exploring the possibilities of exploiting supercritical fluids as a particular media for analysis, purifications and synthesis


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Supercritical Fluid Chromatography : Volume 2

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Supercritical Fluid Chromatography (SFC) provides a timely overview of SFC application areas which were unimaginable just a decade ago. This two-volume series opens with an overview of the history and expectant future of SFC and continues with recent applications in the pharmaceutical industry and other fascinating areas of science. SFC has found its place in the pharmaceutical industry with an increasing body of applications for chiral and achiral molecules in both the research and development phases of the drug discovery process. As illustrated in this two-volume series, the current interest in SFC extends well beyond the pharmaceutical industry. Chapters encompassing applications for polar and non-polar mixtures of importance are covering widely disparate areas in substance abuse, natural products including cannabinoids, bioactive lipids, flavor and fragrance. With its broad balance and coverage, this two-volume book constitutes a unique educational platform to students and scientists for many years to come. The major objective of this book editions is to inspire and stimulate readers to continue exploring the possibilities of exploiting supercritical fluids as a particular media for analysis, purifications and synthesis


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Supercritical Fluid Chromatography

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Abstract

Supercritical Fluid Chromatography (SFC) provides a timely overview of SFC application areas which were unimaginable just a decade ago. This two-volume series opens with an overview of the history and expectant future of SFC and continues with recent applications in the pharmaceutical industry and other fascinating areas of science. SFC has found its place in the pharmaceutical industry with an increasing body of applications for chiral and achiral molecules in both the research and development phases of the drug discovery process. As illustrated in this two-volume series, the current interest in SFC extends well beyond the pharmaceutical industry. Chapters encompassing applications for polar and non-polar mixtures of importance are covering widely disparate areas in substance abuse, natural products including cannabinoids, bioactive lipids, flavor and fragrance. With its broad balance and coverage, this two-volume book constitutes a unique educational platform to students and scientists for many years to come. The major objective of this book editions is to inspire and stimulate readers to continue exploring the possibilities of exploiting supercritical fluids as a particular media for analysis, purifications and synthesis


Digital
Advanced Characterization Techniques, Diagnostic Tools and Evaluation Methods in Heritage Science
Authors: ---
ISBN: 9783319753164 Year: 2018 Publisher: Cham Springer International Publishing

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This book details the application of advanced characterisation techniques and diagnostic tools to heritage science, including the evaluation of heritage assets’ condition, their preservation and restoration. It examines the use of electrochemical techniques in conservation science, with a particular focus on how to solve problems in taking on-site measurements. Specifically, it introduces readers to a new gel polymer (GPE) electrochemical cell developed by the authors for the characterisation of metallic heritage objects. Other techniques used to characterise and monitor reinforced concrete objects in more modern buildings are also covered, including non-destructive electrochemical techniques that allow steel corrosion to be assessed in these structures, and in those that are used to protect and repair such buildings. The usefulness of the NMR-Mouse nuclear magnetic resonance sensor in the assessment and preservation of softer heritage materials, such as wood, parchment, bone, and painted walls, is covered, as well as Infrared reflectography for examining paintings and laser cleaning for restoring them. The book introduces ultra-High Performance Liquid Chromatography (u-HPLC) with a diode-array (DAD) and mass–mass (MS-MS) quadruple time-of-flight spectroscopy (QTOF). This new technique can be applied to the analysis and identification of natural and synthetic organic pigments and its use is demonstrated in several case studies. This book provides a rigorous scientific grounding in the application of state-of-the-art techniques in heritage science and conservation, and offers a practical handbook for practitioners.


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Analytical Methods for the Assessment of Maillard Reactions in Foods
Authors: --- --- --- ---
ISBN: 9783319769233 Year: 2018 Publisher: Cham Springer International Publishing

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This Brief provides an overview of different analytical methods and techniques for the qualitative and quantitative evaluation of Maillard Reactions and their reaction products in foods during processing and storage. Reliable methodology for the investigation of Maillard Reactions and their products are of utmost importance in food analysis: since Maillard Reactions can on the one hand be desirable and advantageous, influencing the colors, flavors and odors of food products, they can on the other hand also produce detrimental compounds afflicting the consumers’ health (e.g. furfurals, furosine, or acrylamide). This Brief introduces different analytical methods, which can be used to investigate and characterize Maillard Reactions and their products in foods, including for example capillary electrophoresis, high performance liquid chromatography, gas chromatography with mass spectrometric detection, UV-VIS spectrophotometry, fluorescence, electronic nose, gravimetric systems, and many more. The chapters exemplify how the analytical techniques can be applied for assessing and evaluating different Maillard Reaction products in foods. Readers will find basic information, as well as practical hints and guidelines for application in their own laboratory.


Book
Omics technologies and bio-engineering
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ISBN: 0128047496 0128046597 9780128047491 9780128046593 Year: 2018 Publisher: London


Book
Principles of instrumental analysis
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ISBN: 9781305577213 1305577213 8000010402 1337468037 9789353506193 9353506190 Year: 2018 Publisher: Australia : Cengage Learning

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This book places an emphasis on operating principles of each type of instrument, its optimal area of application, its sensitivity, its precision, and its limitations. You'll also learn about elementary analog and digital electronics, computers, and the treatment of analytical data. The book companion website has supplemental tutorials on instrumental methods, Excel files of data analysis and simulations of analytical techniques to help you visualize important concepts in this course, and selected papers from the chemical literature to stimulate interest.

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