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This volume addresses the various techniques and novel applications of mass spectrometry imaging (MSI) and its role as a discovery tool in the field of proteomics, lipidomics, and metabolomics. The chapters in this book demonstrate how MSI can be applied to many areas of research such as clinical pathology, translational medicine, toxicology, biomarkers and response studies, and potential incorporation of MSI into forensic workflows. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Innovative and comprehensive, Imaging Mass Spectrometry: Methods and Protocols is a valuable resource for research scientists and clinicians who are interested in further studies of MSI technologies.

Radiology, Medical. --- Imaging / Radiology. --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics

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This book focuses on with musculoskeletal imaging: during the last few years, there have been considerable advances in this area, driven by clinical as well as technological developments. The authors, internationally renowned experts in their field, have contributed chapters that are disease-oriented and cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As a result, this book offers a comprehensive review of the state of the art in musculoskeletal imaging. It is a valuable resource for general radiologists, radiology residents, rheumatologists, orthopaedic surgeons, and clinicians from other specialities wishing to update their knowledge in this discipline.

Medicine. --- Radiology. --- Orthopedics. --- Medicine & Public Health. --- Imaging / Radiology. --- Musculoskeletal system --- Diseases. --- Radiology, Medical. --- Orthopaedics --- Orthopedia --- Surgery --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Radiological physics --- Physics --- Radiation

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This superbly illustrated book offers comprehensive and systematic coverage of the pitfalls that may arise during musculoskeletal imaging, whether as a consequence of the imaging technique itself or due to anatomical variants or particular aspects of disease. The first section is devoted to technique-specific artifacts encountered when using different imaging modalities and covers the entire range of advanced methods, including high-resolution ultrasonography, computed tomography, magnetic resonance imaging, and positron emission tomography. Advice is provided on correct imaging technique. In the second section, pitfalls in imaging interpretation that may occur during the imaging of trauma to various structures and of the diseases affecting these structures are described. Misleading imaging appearances in such pathologies as inflammatory arthritides, infections, metabolic bone lesions, congenital skeletal dysplasias, tumors and tumor-like conditions are highlighted, and normal variants are also identified. Pitfalls in Musculoskeletal Radiology will be an invaluable source of information for the practicing radiologist, facilitating recognition of pitfalls of all types and avoidance of diagnostic errors and misinterpretations, with their medicolegal implications.

Medicine. --- Radiology. --- Orthopedics. --- Medicine & Public Health. --- Diagnostic Radiology. --- Radiology, Medical. --- Orthopaedics --- Orthopedia --- Surgery --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Radiological physics --- Physics --- Radiation

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This richly illustrated book summarizes the state of the art in brain MRI with the 3-Tesla high-field scanner. The aim is to clarify the numerous advantages of using a 3-T high magnetic field MR scanner, especially in terms of sensitivity and specificity. The first section describes techniques for standard MR examination of the brain. Full descriptions are then provided of advanced protocols such as MR angiography, diffusion-weighted imaging (DWI), perfusion-weighted imaging (PWI), MR spectroscopy, MR tractography, and functional imaging. Differences in diagnostic features when performing these examinations at 3 T and at 1.5 T are highlighted. In addition, safety issues relating to the installation and use of a high-field scanner are discussed. The second section then describes and illustrates in detail each of the main clinical applications of 3-T MRI in the human brain: trauma, stroke, white matter disease, Parkinson’s disease, Alzheimer’s disease, brain tumors, inflammatory disease, psychiatric disorders, etc. A final chapter is dedicated to the evaluation of 7-T MRI within both research and potential clinical settings. The book will be a valuable tool for general radiologists, neuroradiologists, trainees, and technicians.

Brain --- Diseases --- Diagnosis. --- Medicine. --- Neuroradiology. --- Neurology. --- Medicine & Public Health. --- Radiology, Medical. --- Medicine --- Nervous system --- Neuropsychiatry --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Neurology . --- Neuroradiography --- Neuroradiology

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This atlas presents normal imaging variations of the brain, skull, and craniocervical vasculature. Magnetic resonance (MR) imaging and computed tomography (CT) have advanced dramatically in the past 10 years, particularly in regard to new techniques and 3D imaging. One of the major problems experienced by radiologists and clinicians is the interpretation of normal variants as compared with the abnormalities that the variants mimic. Through an extensive collection of images, this book offers a spectrum of appearances for each variant with accompanying 3D imaging for confirmation; explores common artifacts on MR and CT that simulate disease; discusses each variant in terms of the relevant anatomy; and presents comparison cases for the purpose of distinguishing normal findings from abnormalities. It includes both common variants as well as newly identified variants that are visualized by recently developed techniques such as diffusion-weighted imaging and multidetector/multislice CT. The book also highlights normal imaging variants in pediatric cases. Atlas of Normal Imaging Variations of the Brain, Skull, and Craniocervical Vasculature is a valuable resource for neuroradiologists, neurologists, neurosurgeons, and radiologists in interpreting the most common and identifiable variants and using the best methods to classify them expediently. .

Medicine. --- Radiology. --- Neuroradiology. --- Neurology. --- Medicine & Public Health. --- Diagnostic Radiology. --- Neuroradiography --- Neuroradiology --- Radiological physics --- Clinical sciences --- Medical profession --- Radiology, Medical. --- Medicine --- Nervous system --- Neuropsychiatry --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Diseases --- Neurology . --- Physics --- Radiation --- Radiography.