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Cet ouvrage propose 55 démarches cliniques pratiques avec présentation et argumentation des différentes options diagnostiques et thérapeutiques se basant sur les connaissances scientifiques actuelles et les recommandations préconisées par les différentes organisations nationales (HAS) ou internationales (ADA/EASD). Chaque cas clinique est ainsi organisé : - (1) Point de départ - Description du cas clinique précédé par un bref " chapeau " d'introduction rappelant " l'état de l'art " : rappel épidémiologique, physiopathologique, clinique et thérapeutique. - (2) Itinéraire de la démarche à partir du point de départ - Commentaire du cas clinique par l'expert, suivi par une argumentation pour ou contre les différentes solutions proposées en se basant sur le raisonnement scientifique et sur les recommandations. - (3) Point d'arrivée - Enoncé de la solution sur laquelle l'expert a porté son choix préférentiel. Il faut savoir que la validation de ce choix se fera " in fine " sur la meilleure efficience diagnostique ou thérapeutique. - (4) Conclusion et évolution possible au cours des années à venir. Du sujet chez lequel on découvre un diabète de type 2 ou d'une femme diabétique souhaitant conduire une grossesse en passant par le sujet diabétique insuliné en hémodialyse ou ayant une rétinopathie sévère, les 55 démarches cliniques proposées correspondent à la majorité des situations auxquelles sont confrontés les médecins en pratique médicale courante.

Diabetes Mellitus --- General Practice --- Family practice --- Diabètes --- Médecine générale --- Études de cas --- Présentations de cas --- Diabetes Mellitus. --- Family Practice. --- Médecine générale. --- Diabetes Mellitus - case reports --- Family Practice --- Diabetes

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Compassion is an attribute of a person’s affective understanding, which aims to enable, so far as possible, shared experiences of the world’s ills and some alleviation of those ills’ effects.Such an attribute is thus of great value within healthcare institutions such as general practicesand other primary and community healthcare settings. It may characterise the peoplewho participate in those institutions; or, it may not so characterise them. The appearanceof compassion, under certain conditions and even in fragile and incomplete forms, is a kindof human excellence, a way of being for the good in community.* Compassion is not, therefore,a commodity, to be bought, sold and traded. Although time can be costed, there is noline for compassion in any budget. Were compassion to be thought a commodity, one couldimagine trading it off against some more measurable factor (efficiency, cost-effectiveness, etc.).However, our human capacity for compassion, though fragile, tends to resist such marginalisationand reductionism.

Primary Health Care --- Family Practice --- General Practice --- ethics --- community healthcare --- primary healthcare --- compassion --- Decision-making --- General practitioner --- Shared Experience

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Edited by the same team that developed the successful Pediatric Dialysis and its second edition, this text features clinical management principles that are integral to the care of children receiving chronic dialysis. Each chapter is introduced by a case presentation that serves as the basis for key learning points that are clinically applicable and presented in a succinct manner. The topics included in Pediatric Dialysis Case Studies cover virtually all aspects of pediatric dialysis care and represent the efforts of an international group of experts with firsthand clinical expertise from all disciplines represented in the pediatric dialysis team. This resource is certain to help the clinician achieve improved outcomes for these often complex patients.

Family medicine. --- Family practice (Medicine) --- General practice (Medicine) --- Medicine. --- General practice (Medicine). --- Nephrology. --- Pediatrics. --- Medicine & Public Health. --- General Practice / Family Medicine. --- Medicine --- Physicians (General practice) --- Paediatrics --- Pediatric medicine --- Children --- Internal medicine --- Kidneys --- Diseases --- Health and hygiene --- Family medicine

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This book tells the intriguing and often colorful stories of the medical words we use. The origins of clinical and scientific terms can be found in Greek and Latin myths, in places such as jungles of Uganda and the islands of the Aegean Sea, in the names of medicine’s giants such as Hippocrates and Osler, and in some truly unlikely sources. In this book you will learn the answers to questions such as: • What disease was named for an American space flight? • Do you know the echoic word for elephantine rumbling of the bowels? • What drug name was determined by drawing chemists’ notes out of a hat? • What are surfer’s eye, clam digger’s itch, and hide porter’s disease? This book can give you new insights into the terms we use every day in the clinic, hospital, and laboratory. Knowing a word’s history assists in understanding not only what it means, but also some of the connotative subtleties of terms used in diagnosis and treatment. The Amazing Language of Medicine is intended for the enrichment of physicians, other health professionals, students, and anyone involved in clinical care and medical science.

Medicine. --- General practice (Medicine). --- Primary care (Medicine). --- Medicine --- Medicine & Public Health. --- History of Medicine. --- General Practice / Family Medicine. --- Primary Care Medicine. --- History. --- Primary medical care --- Clinical sciences --- Medical profession --- Family medicine. --- Emergency medicine. --- Health Workforce --- Medicine, Emergency --- Critical care medicine --- Disaster medicine --- Medical emergencies --- Family practice (Medicine) --- General practice (Medicine) --- Physicians (General practice) --- Medicine—History. --- Medical care --- Family medicine

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This new edition now titled “Human Chromosome Variation: Heteromorphism, Polymorphism and Pathogenesis” provides the reader with an up-to-date overview of microarrays, fragile sites, copy number variations and whole genome sequencing. Greatly expanding the discussion of microarray analysis in the previous edition of the book, are new chapters on microarray and genomic analysis, plus comprehensive tables on the subtle microdeletions and microduplications that are found on each chromosome, including 235 recurring copy number variants that are associated with well-established or emerging chromosomal syndromes. The current edition features concise information on cytogenetic methods and applications, extending these discussions to DNA analysis and genome sequencing. Sections on euchromatin, heterochromatin, FISH pattern, fragile site, copy number, and DNA sequence variation are integrated with actual clinical examples from cytogenetic laboratories and from clinical practice. The principles that allow for the distinction between benign chromosome / DNA variation and pathogenic heteromorphisms / polymorphisms are discussed and include references to the latest organizational guidelines and genomic or population databases. The two previous incarnations of this book: the ‘Atlas of Human Chromosome Heteromorphism’, and ‘Human Chromosome Variation: Heteromorphism and Polymorphism’ have been standard reference works in most cytogenetic laboratories, used by laboratory directors and clinicians all around the world. While widely used sections from the previous edition on cytogenetic technologies and heteromorphisms are retained intact the present volume adds extensive material on copy number variations (polymorphisms detected by microarray analysis), fragile sites in disease and cancer, and practical views on interpreting emerging technologies, including whole exome sequencing. This book should be of interest to clinicians, technicians and students who are or will be exposed to DNA and/or chromosome analysis and the data derived from these continuously developing techniques. This fully updated book volume will bring the reader up to speed on the latest technologies, their applications, benefits and drawbacks and as such, is a must read for anyone with an interest in DNA and chromosome analysis and the distinction between benign variation and pathogenic mistakes.

Medicine. --- Medical genetics. --- General practice (Medicine). --- Biomedicine. --- Gene Function. --- General Practice / Family Medicine. --- Human genetics --- Variation. --- Genetic variation in humans --- Variation (Biology) --- Family medicine. --- Family practice (Medicine) --- General practice (Medicine) --- Medicine --- Physicians (General practice) --- Clinical genetics --- Diseases --- Heredity of disease --- Medical sciences --- Pathology --- Genetic disorders --- Genetic aspects