Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Membrane Proteins --- Membrane Proteins --- immunology. --- physiology.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Ion channels. --- Channels, Ion --- Biological transport, Active --- Ion-permeable membranes --- Membrane proteins

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Ion channels. --- Channels, Ion --- Biological transport, Active --- Ion-permeable membranes --- Membrane proteins

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book has been conceives as a brief introduction to biomembranes physical chemistry for undergraduate students of sciences, and it is particularly dedicated to the lipid-protein membrane interactions. A general introduction is presented in Chapters 1 and 2. The following Chapters, 3 and 4, describe the most accepted theories on lipid-membrane protein interactions as well as the new experimental approaches, in particular, these arose from nano sciences as atomic for microscopy and single molecule force spectroscopy. The book emphasizes the relevance of physical parameters as the lateral surface pressure and the lipid curvature as actors for understanding the physicochemical properties of the biomembranes.

Biochemistry --- Chemistry --- Physical Sciences & Mathematics --- Membrane proteins. --- Lipids. --- Lipid membranes. --- Lipides --- Lipins --- Lipoids --- Lipids --- Membranes (Biology) --- Membranes (Technology) --- Biomolecules --- Steroids --- Proteins --- Biochemistry. --- Bioorganic chemistry. --- Protein Science. --- Bioorganic Chemistry. --- Biological and Medical Physics, Biophysics. --- Bio-organic chemistry --- Biological organic chemistry --- Chemistry, Organic --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Medical sciences --- Composition --- Proteins . --- Biophysics. --- Biological physics. --- Biological physics --- Physics --- Proteids --- Polypeptides --- Proteomics

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book provides new structural, biochemical, and clinical information on ABC transporters. The authors explore and describe the state of the art of research, knowledge, and prospects for the future for this important family of proteins. The first ABC transporter was discovered in 1973 and was named P-glycoprotein. It elicits resistance to cytotoxic drugs, chiefly in human tumours, within which chemotherapy failure is observed in about 50% of cases. Together with its complex pharmacology, and even a suspected role in Alzheimer’s disease, this ABC transporter still eludes a clinical solution to its multidrug resistance property. ABC transporters are integral membrane active proteins and they belong to one of the largest protein families across all species. Their myriad roles encompass the import or export of a diverse range of allocrites, including ion, nutrients, peptides, polysaccharides, lipids, and xenobiotics. They are of major medical importance with many members elaborating multidrug resistance in bacteria, fungi, yeast, parasites, and humans. Other ABC transporters are involved in a number of inherited diseases, including cystic fibrosis, macular degeneration, gout, and several other metabolic disorders.

Cytology --- Biology --- Health & Biological Sciences --- Multidrug resistance. --- ATP-binding cassette transporters. --- ABC proteins --- ABC transporters --- ATP-binding cassette proteins --- Multi-drug resistance --- Multiple drug resistance --- Pleiotropic drug resistance --- Carrier proteins --- Membrane proteins --- Drug resistance --- Cell membranes. --- Biochemistry. --- Drug interactions. --- Membrane Biology. --- Biological and Medical Physics, Biophysics. --- Biochemistry, general. --- Drug Resistance. --- Interactions, Drug --- Drugs --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Cell surfaces --- Cytoplasmic membranes --- Plasma membranes --- Plasmalemma --- Membranes (Biology) --- Glycocalyces --- Side effects --- Composition --- Cell membranes . --- Biophysics. --- Biological physics. --- Drug resistance. --- Resistance to drugs --- Pharmacology --- Biological physics --- Physics