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This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation; large-scale, high-speed MS sample profiling; new methods based on  MALDI or MALDI-like sample preparations; and the advantages of MALDI MS analysis over ESI (electrospray ionization).  This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: • Showcases new techniques and applications in MALDI MS • Demonstrates how MALDI is preferable to ESI • Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and various application areas, such as cancer proteomics.

Biochemistry --- Chemistry --- Physical Sciences & Mathematics --- Mass spectrometry. --- Matrix-assisted laser desorption-ionization. --- Biomolecules --- Analysis. --- MALDI (Spectrum analysis) --- MALDI MS (Spectrum analysis) --- Mass spectra --- Mass spectrograph --- Mass spectroscopy --- Mass spectrum analysis --- Mass (Physics) --- Nuclear spectroscopy --- Spectrum analysis --- Mass spectrometry --- Biochemistry. --- Proteomics. --- Microbiology. --- Biotechnology. --- Protein Science. --- Mass Spectrometry. --- Applied Microbiology. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Medical sciences --- Chemical engineering --- Genetic engineering --- Microbial biology --- Microorganisms --- Molecular biology --- Proteins --- Composition --- Proteins . --- Proteids --- Polypeptides --- Proteomics