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Glaucoma. --- Eye --- Eyeball --- Eyes --- Visual system --- Face --- Photoreceptors --- Vision --- High intraocular pressure --- Intraocular pressure, High --- Diseases --- Prevention.

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"Over the past fifty years, enormous progress has been made in understanding visual mechanisms and treating eye disorders. And yet the scientist is not always aware of the latest clinical advances and the clinician is often not up to date on the basic scientific discoveries. Writing in nontechnical language, John and Joseph Dowling, a neuroscientist and an ophthalmologist, examine vision from both perspectives, providing concise descriptions of basic visual mechanisms and related clinical abnormalities. Thus, an account of the photoreceptors is followed by a consideration of retinitis pigmentosa and macular degeneration; an explanation of the retina's function is followed by details of glaucoma and diabetic retinopathy. The authors begin with the cornea and lens, which project an image on the light-sensitive elements inside the eye, the photoreceptors, and how that process can be compromised by such disorders as cataracts and corneal disease. They go on to describe, among other things, how the photoreceptors capture light; retinal and visual cortical anatomy and physiology; and higher level visual processing that leads to perception. Cortical disorders such as amblyopia are discussed as well as specific deficits such as the inability to recognize faces, colors, or moving objects. Finally, they survey the evolution of our knowledge of vision, and speculate about future advances"--MIT CogNet.

Vision --- Eye --- Ophthalmology --- Neuroscience --- Human Anatomy & Physiology --- Health & Biological Sciences --- Physiology --- Diseases --- Eyeball --- Eyes --- Visual system --- Eyesight --- Seeing --- Sight --- Medicine --- Face --- Photoreceptors --- Senses and sensation --- Blindfolds --- Physiological optics --- NEUROSCIENCE/Visual Neuroscience --- NEUROSCIENCE/General --- BIOMEDICAL SCIENCES/General

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This richly illustrated, comprehensive guide enables the reader to observe anatomy and identify ophthalmic disease with the use of optical coherence tomography (OCT). It is the most up-to-date atlas of OCT images, many of which have been obtained with the newer OCT technologies that offer excellent image quality and definition at a microscopic level. All of the major disease areas in ophthalmology are covered, including diabetic retinopathy, age-related macular degeneration, uveitis, glaucoma, retinal vascular disease, and further hot topics are also considered. The chapters are written by leading international ophthalmologists from renowned academic centers who utilize OCT in their everyday practice, and the numerous high quality OCT images ensure that the reader will easily be able to follow the key issues. Optical Coherence Tomography has emerged as an innovative and powerful imaging technique that allows high-resolution, non-invasive, in vivo cross-sectional imaging in human tissue. This book, with its clinical emphasis, will have wide appeal for residents, fellows, and experienced practitioners in ophthalmology, as well as optometrists, medical students and graduates.

Ophthalmology & Optometry --- Medicine --- Health & Biological Sciences --- Optical coherence tomography. --- Eye --- Diseases --- Treatment. --- Eyeball --- Eyes --- Visual system --- OCT (Tomography) --- Face --- Photoreceptors --- Vision --- Interferometry --- Optical tomography --- Coherence (Optics) --- Ophthalmology. --- Radiology, Medical. --- Imaging / Radiology. --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Radiology. --- Radiological physics --- Physics --- Radiation

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This book comprises an integrated review of ocular therapeutics across all relevant fields. It addresses the real-world requirements of ophthalmologists, pharmacists and optometrists, as observed through working alongside these practitioners for two decades. Knowledge surrounding agents used in ophthalmic practice has, historically, been scattered. The book facilitates understanding of ocular drug therapy by compiling all key aspects of the pharmacology, toxicology, pharmaceutical science, ocular biochemistry and cell biology of these agents. Chapters detail drug transfer across barriers, systemic toxicity of topically applied drugs, autonomic drugs used for diagnostics, as well as anti-inflammatory, antiallergic, glaucoma and antimicrobial therapies, and avenues for the development of new ocular drugs. Applications of extemporaneously prepared formulations are described to inform day-to-day clinical practice. The use of mucoadhesive polymers in tear substitutes, ocular drug delivery systems, stem cell therapy, pharmacogenomics and antiangiogenic ocular chemotherapy are also explored. The book also provides insights from drugs of herbal origin, and a historical perspective on drugs for ocular use. Practicing and resident ophthalmologists, optometrists, pharmacists, nursing professionals, scholars in ocular drug research and students will equally benefit from this comprehensive guide.

Pharmacy, Therapeutics, & Pharmacology --- Health & Biological Sciences --- Toxicology. --- Ophthalmology. --- Pharmacology/Toxicology. --- Medicine --- Eye --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Diseases --- Toxicology --- Ocular pharmacology. --- Ophthalmic drugs. --- Treatment. --- Eyeball --- Eyes --- Visual system --- Face --- Photoreceptors --- Vision --- Materia medica, Ophthalmological --- Ophthalmic agents --- Drugs --- Therapeutics, Ophthalmological --- Ocular pharmacology --- Ophthalmopharmacology --- Ophthalmic drugs --- Drug effects --- Effect of drugs on --- Pharmacology. --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Pharmacy --- Physiological effect

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This book describes experimental animal models that mimic common human ocular diseases: herpetic keratitis, cataract, glaucoma, age-related macular degeneration, diabetic retinopathy, uveitis, retinitis pigmentosa, Graves’ disease, and intraocular tumors.  In conjunction, these models reflect the diversity and utility of tools used to study human disease.  World expert clinicians discuss each model based on their clinical experience, and the text is supported by numerous photos and diagrams.  Development of suitable experimental models is critical in identifying risk factors for disease, elucidating fundamental molecular mechanisms in disease progression, and providing guidance as to whether or not a particular treatment is safe and effective for humans. Like other forms of medical research, ophthalmology and vision research focuses on the investigation of disease pathogenesis and the discovery of novel therapies through in vitro and in vivo methodology.  The in vivo experiments employ animal models including vertebrates (zebrafish, rodents, rabbits, and primates) and invertebrates (fruit flies and nematodes) for drug screening. In describing the most pertinent animal models of ophthalmic diseases, this book will be of interest to ophthalmologists, vision researchers, fellows, residents, and medical students.

Ophthalmology & Optometry --- Medicine --- Health & Biological Sciences --- Eye --- Diseases --- Animal models. --- Eyeball --- Eyes --- Visual system --- Face --- Photoreceptors --- Vision --- Ophthalmology. --- Laboratory animals. --- Animal Models. --- Animals, Experimental --- Animals, Laboratory --- Animals in research --- Experimental animals --- Lab animals --- Animal culture --- Laboratory organisms --- Working animals --- Animal experimentation --- Animal models in research. --- Biological models --- Laboratory animals --- Research