Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

In 1990, scientists began working together on one of the largest biological research projects ever proposed. The project proposed to sequence the three billion nucleotides in the human genome. The Human Genome Project took 13 years and was completed in April 2003, at a cost of approximately three billion dollars. It was a major scientific achievement that forever changed the understanding of our own nature. The sequencing of the human genome was in many ways a triumph for technology as much as it was for science. From the Human Genome Project, powerful technologies have been developed (e.g., microarrays and next generation sequencing) and new branches of science have emerged (e.g., functional genomics and pharmacogenomics), paving new ways for advancing genomic research and medical applications of genomics in the 21st century. The investigations have provided new tests and drug targets, as well as insights into the basis of human development and diagnosis/treatment of cancer and several mysterious humans diseases. This genomic revolution is prompting a new era in medicine, which brings both challenges and opportunities. Parallel to the promising advances over the last decade, the study of the human genome has also revealed how complicated human biology is, and how much remains to be understood. The legacy of the understanding of our genome has just begun. To celebrate the 10th anniversary of the essential completion of the Human Genome Project, in April 2013 Genes launched this Special Issue, which highlights the recent scientific breakthroughs in human genomics, with a collection of papers written by authors who are leading experts in the field.

Human genome. --- Genomes --- Human chromosomes

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Genetics. --- Genetics --- Genetic research --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Research.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Human genetics is not the playground of science alone. Genetics concerns all of us, for we all have DNA, genes, genomes, and chromosomes. Our genes determine partly our appearance and our behaviour, our talents and our health risks.The authors of The Human Recipe use humour to explain what we understand about human genetics. With anecdotes and topical examples, they demonstrate how genetics affects our everyday lives. What if a DNA analysis were to reveal that your biological father must be someone other than the person you’ve been calling “Dad” for years? Does genetics explain why Africans excel in athletics, Asians in gymnastics, and Europeans mainly in sports testing physical strengths? What is the difference between a genetic disease and a contagious illness?The newest developments in human genetics also raise ethical questions and issues which are currently being debated within the genetics community, and the authors do not avoid looking at these either. Should we use genetics to ensure the conception of healthy children or even “designer babies”? Should we identify genetic risks before pregnancy? Should we edit genes in embryos? Can we identify our risk for cancers and can we prevent them? What about privacy in DNA research and forensic databases? Can DNA be stolen, and if so, would this be considered a serious crime? The Human Recipe provides a clever insight into all you might want to know about human genetics in our current society.

Human genome --- Genes --- Genetics. --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Units of heredity --- Units of inheritance --- Molecular genetics --- DNA --- Genomes --- Human chromosomes --- Social aspects. --- menselijk genoom --- genetica (genen) --- genetisch onderzoek --- genetisch patent --- génome humain --- génétique (gènes) --- recherche génétique --- brevet génétique --- Genetica --- Genetisch onderzoek --- Human genetics --- Genetics

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book is a broadly historical account of a remarkable and very exciting scientific story–the search for the number of human chromosomes. It covers the processes and people, culminating in the realization that discovering the number of human chromosomes brought as much benefit as unraveling the genetic code itself.  With the exception of red blood cells, which have no nucleus and therefore no DNA, and sex cells, humans have 46 chromosomes in every single cell. Not only do chromosomes carry all of the genes that code our inheritance, they also carry them in a specific order. It is essential that the number and structure of chromosomes remains intact, in order to pass on the correct amount of DNA to succeeding generations and for the cells to survive. Knowing the number of human chromosomes has provided a vital diagnostic tool in the prenatal diagnosis of genetic disorders, and the search for this number and developing an understanding of what it means are the focus of this book.

Chromosomes --- Genetics --- Cellular Structures --- Intranuclear Space --- Biology --- Genetic Structures --- Cells --- Biological Science Disciplines --- Genetic Phenomena --- Cell Nucleus Structures --- Cell Nucleus --- Natural Science Disciplines --- Phenomena and Processes --- Anatomy --- Intracellular Space --- Disciplines and Occupations --- Cytology --- Health & Biological Sciences --- Human chromosomes. --- Human genetics --- History. --- Human genetics. --- Cytology. --- History of Science. --- Human Genetics. --- Cell Biology. --- Cell biology --- Cellular biology --- Cytologists --- Heredity, Human --- Human biology --- Physical anthropology --- Annals --- Auxiliary sciences of history --- Cell biology.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

All animals, including humans, derive from a single cell, which possesses all the genetic instructions needed to define how the animal will look like. However, during development, the millions of cells that derive from the zygote will only select part of this genetic information to give rise to the various organs of the body. The coordination of different cell behaviours during development results in the formation of specialized tissues and organs giving rise to highly adapted animals. This book provides an overview of how this diversification is achieved during organ formation and how it may have evolved. Conserved cellular processes are presented using examples from selected vertebrate and invertebrate species that illustrate how developmental biologists are solving the complex puzzle of organ formation. This volume is aimed to students, researchers and medical doctors alike who want to find a simple but rigorous introduction on how gene networks control organ formation.

Medicine. --- Medical genetics. --- Embryology. --- Biomedicine. --- Gene Function. --- Genetics. --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Animal embryology --- Animals --- Development, Embryological --- Development, Embryonic --- Development, Zygotic --- Embryogenesis --- Embryogeny --- Embryological development --- Embryonic development --- Zoology --- Zygote development --- Zygotes --- Zygotic development --- Zygotic embryogenesis --- Developmental biology --- Morphology (Animals) --- Embryos --- Reproduction --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Development --- Genetic aspects