Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Les pays développés se sont engagés à mobiliser ensemble 100 milliards USD par an d’ici à 2020 afin de financer les efforts de lutte contre le changement climatique dans les pays en développement. Cinq ans après l’annonce de cet engagement, qui a été faite à Copenhague en 2009 lors de la COP15, et six ans avant la date butoir de 2020, ce rapport présente un état des lieux du financement climatique mobilisé à cette fin par les pays développés en 2013 et 2014. Des avancées non négligeables ont été réalisées vers cet objectif. Selon les estimations préliminaires que présente ce rapport, le financement climatique a atteint 62 milliards USD en 2014 et 52 milliards USD en 2013, ce qui équivaut à une moyenne de 57 milliards USD par an pour ces deux années. Le rapport s‘attache à faire preuve de transparence et de rigueur dans l’analyse des données disponibles et le choix des hypothèses et des méthodes sous-jacente, malgré les limites que peut imposer un exercice de notification globale. Les approches méthodologiques et les activités de collecte de données nécessaires pour étayer l’élaboration d’estimations de cette nature vont en s’améliorant. Comme le souligne le rapport, il reste néanmoins des efforts importants à faire pour parvenir à établir des estimations plus complètes et plus justes à l’avenir. L’OCDE et CPI sont prêts à appuyer cet effort.

Nature and nurture. --- Euthenics. --- Environment --- Human beings --- Eugenics --- Genetics and environment --- Heredity and environment --- Nature --- Nature versus nurture --- Nurture and nature --- Genetics --- Heredity --- Effect of environment on --- Nurture --- Environmental effects on human beings --- Environment and genetics --- Environment and heredity

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Translating Gene Therapy to the Clinic, edited by Dr. Jeffrey Laurence and Michael Franklin, follows the recent, much-lauded special issue of Translational Research in emphasizing clinical milestones and critical barriers to further progress in the clinic. This comprehensive text provides a background for understanding the techniques involved in human gene therapy trials, and expands upon the disease-specific situations in which these new approaches currently have the greatest therapeutic application or potential, and those areas most in need of future research. It emphasizes methods, tools,

Gene therapy. --- Human genetics. --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Therapy, Gene --- Genetic engineering --- Therapeutics

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Regulatory Non-Coding RNAs: Methods and Protocols offers a collection of methods for those interested in the discovery, localization, and functional analysis of these non-coding transcripts that have the potential and ability to orchestrate and control gene expression. After a review of the field, this detailed volume continues with methods useful for the study of siRNAs, microRNAs, and their targets, techniques concerned with long non-coding RNAs, as well as studies of the critical parameters of functional non-coding RNA protein-RNA interactions and the environment in which they act. Written for the highly successful Methods in Molecular Biology series, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.   Dependable and easy to use, Regulatory Non-Coding RNAs: Methods and Protocols provides a current, state-of-the-art collection of methods and approaches that will be of value to researchers in this expanding and fascinating field.

Human genetics. --- Human Genetics. --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This volume contains state-of-the-art methods tackling all aspects of small non-coding RNAs biology.  Small Non-Coding RNAs: Methods and Protocols guides readers through customized dedicated protocols and technologies that will be of valuable help to all those willing to contribute deciphering the numerous functions of small non-coding RNAs. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubles troubleshooting and avoiding known pitfalls. Instructive and practical, Small Non-Coding RNAs: Methods and Protocols reaches out to biochemists, cellular, and molecular biologists already working in the field of RNA biology  and to those just starting to study small non-coding RNAs.

Human genetics. --- Human Genetics. --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This fourth edition reflects the most recent technical advances in DNA-protein interaction research. With fully updated chapters that describe techniques proven by their continuous value, the volume also many new chapters have been added that mostly deal with larger-scale experiments, reflecting recent advances in "big biology", combining to offer a very useful compendium of protocols allowing readers to delve into the intricacies of protein-DNA interaction at levels ranging from the very small (as in the case of single-molecule FRET) to the very complex (as with circular chromatin conformation capture, or 4C). Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, DNA-Protein Interactions: Principles and Protocols, Fourth Edition will aid researchers in continuing the incredible progress made in this vital area of study.

Human genetics. --- Proteomics. --- Human Genetics. --- Molecular biology --- Proteins --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology