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Book
The genealogy of a gene
Author:
ISBN: 0262533782 0262327198 0262327201 9780262327190 9780262028660 0262028662 9780262327206 9780262533782 Year: 2015 Publisher: Cambridge, Massachusetts

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Abstract

In The Genealogy of a Gene, Myles Jackson uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping the varied "genealogy" of CCR5 -- intellectual property, natural selection, Big and Small Pharma, human diversity studies, personalized medicine, ancestry studies, and race and genomics -- Jackson links a myriad of diverse topics. The history of CCR5 from the 1990s to the present offers a vivid illustration of how intellectual property law has changed the conduct and content of scientific knowledge, and the social, political, and ethical implications of such a transformation. The CCR5 gene began as a small sequence of DNA, became a patented product of a corporation, and then, when it was found to be an AIDS virus co-receptor with a key role in the immune system, it became part of the biomedical research world -- and a potential moneymaker for the pharmaceutical industry. When it was further discovered that a mutation of the gene found in certain populations conferred near-immunity to the AIDS virus, questions about race and genetics arose. Jackson describes these developments in the context of larger issues, including the rise of "biocapitalism," the patentability of products of nature, the difference between U.S. and European patenting approaches, and the relevance of race and ethnicity to medical research.

Keywords

AIDS (Disease) --- Genes. --- Genes --- Genetic genealogy. --- HIV (Viruses) --- AIDS-associated retrovirus --- AIDS virus --- ARV (Viruses) --- HTLV-III (Viruses) --- HTLV-III-LAV (Viruses) --- Human immunodeficiency viruses --- Human T-cell leukemia virus III --- Human T-cell lymphotropic virus III --- Human T-lymphotropic virus III --- IDAV (Viruses) --- Immunodeficiency-associated virus --- LAV (Viruses) --- LAV-HTLV-III (Viruses) --- Lymphadenopathy-associated virus --- T-lymphotrophic virus III, Human --- DNA and genealogy --- DNA genealogy --- DNA in genealogy --- Genetics and genealogy --- Genetics in genealogy --- Units of heredity --- Units of inheritance --- Acquired immune deficiency syndrome --- Acquired immunodeficiency syndrome --- Acquired immunological deficiency syndrome --- HTLV (Viruses) --- Virus-induced immunosuppression --- Genealogy --- Heredity --- Molecular genetics --- DNA --- HIV infections --- Immunological deficiency syndromes --- Receptors, CCR5 --- Patents as Topic. --- HIV Infections. --- Continental Population Groups --- Acquired Immunodeficiency Syndrome. --- genetics. --- Acquired Immune Deficiency Syndrome --- Acquired Immuno-Deficiency Syndrome --- AIDS --- Immunodeficiency Syndrome, Acquired --- Immunologic Deficiency Syndrome, Acquired --- Acquired Immuno Deficiency Syndrome --- Acquired Immuno-Deficiency Syndromes --- Acquired Immunodeficiency Syndromes --- Immuno-Deficiency Syndrome, Acquired --- Immuno-Deficiency Syndromes, Acquired --- Immunodeficiency Syndromes, Acquired --- Syndrome, Acquired Immuno-Deficiency --- Syndrome, Acquired Immunodeficiency --- Syndromes, Acquired Immuno-Deficiency --- Syndromes, Acquired Immunodeficiency --- CD4-Positive T-Lymphocytes --- HIV-1 --- AIDS Arteritis, Central Nervous System --- HIV Coinfection --- HTLV-III Infections --- HTLV-III-LAV Infections --- T-Lymphotropic Virus Type III Infections, Human --- Coinfection, HIV --- Coinfections, HIV --- HIV Coinfections --- HIV Infection --- HTLV III Infections --- HTLV III LAV Infections --- HTLV-III Infection --- HTLV-III-LAV Infection --- Infection, HIV --- Infection, HTLV-III --- Infection, HTLV-III-LAV --- Infections, HIV --- Infections, HTLV-III --- Infections, HTLV-III-LAV --- T Lymphotropic Virus Type III Infections, Human --- Trademarks --- Patents as Topics --- Trademark --- Human population genetics. --- Patents. --- SCIENCE, TECHNOLOGY & SOCIETY/History of Science --- BIOMEDICAL SCIENCES/General --- SOCIAL SCIENCES/Political Science/Public Policy & Law --- Human genetics --- Population genetics --- Philosophy of science


Book
Thirty years of the HIV/AIDS epidemic in Argentina : an assessment of the national health response
Authors: --- ---
ISBN: 1464805970 1464805962 Year: 2015 Publisher: Washington, DC : World Bank,

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Abstract

The 1992 creation of the National HIV/AIDS Program was a fundamental step for Argentina to reach the second lowest burden of HIV/AIDS in South America. From 2000 to 2010, Argentina further reduced the already low HIV/AIDS incidence of 15.9 per 100,000 by 25 percent and reduced the burden by 21 percent. This study analyzes the national and inter-provincial burden of disease, the demographics of new HIV cases, the demand and supply-sides of service delivery, and conducts a cost-benefit analysis of the National HIV/AIDS Program over the last decade. Though the National HIV/AIDS Program was an ins

Keywords

AIDS (Disease) -- Argentina -- Epidemiology. --- HIV infections -- Argentina. --- Medicine. --- AIDS (Disease) --- HIV infections --- Sexually Transmitted Diseases, Viral --- Immunologic Deficiency Syndromes --- Lentivirus Infections --- Slow Virus Diseases --- Retroviridae Infections --- Sexually Transmitted Diseases --- Immune System Diseases --- Virus Diseases --- Diseases --- RNA Virus Infections --- Acquired Immunodeficiency Syndrome --- HIV Infections --- Public Health --- Health & Biological Sciences --- Communicable Diseases --- Epidemiology --- Argentina --- HTLV-III Infections --- HTLV-III-LAV Infections --- T-Lymphotropic Virus Type III Infections, Human --- HIV Infection --- HTLV III Infections --- HTLV III LAV Infections --- HTLV-III Infection --- HTLV-III-LAV Infection --- Infection, HIV --- Infection, HTLV-III --- Infection, HTLV-III-LAV --- Infections, HIV --- Infections, HTLV-III --- Infections, HTLV-III-LAV --- T Lymphotropic Virus Type III Infections, Human --- Acquired Immune Deficiency Syndrome --- Acquired Immuno-Deficiency Syndrome --- AIDS --- Immunodeficiency Syndrome, Acquired --- Immunologic Deficiency Syndrome, Acquired --- Acquired Immuno Deficiency Syndrome --- Acquired Immuno-Deficiency Syndromes --- Acquired Immunodeficiency Syndromes --- Immuno-Deficiency Syndrome, Acquired --- Immuno-Deficiency Syndromes, Acquired --- Immunodeficiency Syndromes, Acquired --- Syndrome, Acquired Immuno-Deficiency --- Syndrome, Acquired Immunodeficiency --- Syndromes, Acquired Immuno-Deficiency --- Syndromes, Acquired Immunodeficiency --- Infections, RNA Virus --- Infection, RNA Virus --- RNA Virus Infection --- Virus Infection, RNA --- Virus Infections, RNA --- Viral Diseases --- Viral Infections --- Virus Infections --- Disease, Viral --- Disease, Virus --- Diseases, Viral --- Diseases, Virus --- Infection, Viral --- Infection, Virus --- Infections, Viral --- Infections, Virus --- Viral Disease --- Viral Infection --- Virus Disease --- Virus Infection --- Diseases of Immune System --- Immune Diseases --- Immunological Diseases --- Immune Disorders --- Immunologic Diseases --- Disease, Immune --- Disease, Immune System --- Disease, Immunologic --- Disease, Immunological --- Diseases, Immune --- Diseases, Immune System --- Diseases, Immunologic --- Diseases, Immunological --- Disorder, Immune --- Disorders, Immune --- Immune Disease --- Immune Disorder --- Immune System Disease --- Immunologic Disease --- Immunological Disease --- STDs --- STIs --- Sexually Transmitted Infections --- Venereal Diseases --- Disease, Sexually Transmitted --- Disease, Venereal --- Diseases, Sexually Transmitted --- Diseases, Venereal --- Infection, Sexually Transmitted --- Infections, Sexually Transmitted --- STI --- Sexually Transmitted Disease --- Sexually Transmitted Infection --- Transmitted Infection, Sexually --- Transmitted Infections, Sexually --- Venereal Disease --- Infections, Retroviridae --- Infections, Retrovirus --- Retrovirus Infections --- Infection, Retroviridae --- Infection, Retrovirus --- Retroviridae Infection --- Retrovirus Infection --- Disease, Slow Virus --- Diseases, Slow Virus --- Slow Virus Disease --- Virus Disease, Slow --- Virus Diseases, Slow --- Infections, Lentivirus --- Infection, Lentivirus --- Lentivirus Infection --- Deficiency Syndrome, Immunologic --- Deficiency Syndromes, Antibody --- Deficiency Syndromes, Immunologic --- Immunologic Deficiency Syndrome --- Immunological Deficiency Syndromes --- Antibody Deficiency Syndrome --- Antibody Deficiency Syndromes --- Deficiency Syndrome, Antibody --- Deficiency Syndrome, Immunological --- Deficiency Syndromes, Immunological --- Immunological Deficiency Syndrome --- Syndrome, Antibody Deficiency --- Syndrome, Immunologic Deficiency --- Syndrome, Immunological Deficiency --- Syndromes, Antibody Deficiency --- Syndromes, Immunologic Deficiency --- Syndromes, Immunological Deficiency --- Antibodies --- Sexually Transmitted Disease, Viral --- Viral Sexually Transmitted Disease --- Viral Sexually Transmitted Diseases --- Viral Venereal Diseases --- Venereal Diseases, Viral --- Disease, Viral Venereal --- Diseases, Viral Venereal --- Venereal Disease, Viral --- Viral Venereal Disease --- HIV (Viruses) infections --- HTLV-III infections --- HTLV-III-LAV infections --- Human T-lymphotropic virus III infections --- Acquired immune deficiency syndrome --- Acquired immunodeficiency syndrome --- Acquired immunological deficiency syndrome --- deficiency --- HIV Coinfection --- Coinfection, HIV --- Coinfections, HIV --- HIV Coinfections --- CD4-Positive T-Lymphocytes --- HIV-1 --- AIDS Arteritis, Central Nervous System --- Venereology --- Reproductive Tract Infections --- XMRV Infection --- Xenotropic MuLV-related Virus Infection --- Xenotropic Murine Leukemia Virus-related Virus Infection --- Infection, XMRV --- Infections, XMRV --- XMRV Infections --- Xenotropic MuLV related Virus Infection --- Xenotropic Murine Leukemia Virus related Virus Infection --- Lentivirus infections --- Sexually transmitted diseases --- Immunological deficiency syndromes --- Virus-induced immunosuppression --- Immune System Disorders --- Disorder, Immune System --- Immune System Disorder

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