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Compulsive behavior --- Substance-Related Disorders. --- Behavior, Addictive. --- Compulsive behavior. --- Addictive behavior --- Behavior, Compulsive --- Compulsion (Psychology) --- Addictive Behavior --- Addictive Behaviors --- Behaviors, Addictive --- Substance Addiction --- Drug Abuse --- Drug Addiction --- Drug Dependence --- Drug Habituation --- Drug Use Disorders --- Organic Mental Disorders, Substance-Induced --- Substance Abuse --- Substance Dependence --- Substance Use Disorders --- Abuse, Drug --- Abuse, Substance --- Abuses, Substance --- Addiction, Drug --- Addiction, Substance --- Dependence, Drug --- Dependence, Substance --- Disorder, Drug Use --- Disorder, Substance Use --- Drug Use Disorder --- Habituation, Drug --- Organic Mental Disorders, Substance Induced --- Substance Abuses --- Substance Use Disorder --- addictive behavior --- behavioral research --- psychosocial research --- addiction --- alcoholism --- gambling --- Substance abuse --- Substance abuse. --- Impulse --- Psychology, Pathological --- Obsessive-compulsive disorder --- Prescription Drug Abuse --- Abuse, Prescription Drug --- Drug Abuse, Prescription --- Drug and Narcotic Control --- Disruptive, Impulse Control, and Conduct Disorders --- Psychoses, Alcoholic --- Social Problems --- Street Drugs --- Designer Drugs --- Behavior, Addictive --- Codependency (Psychology) --- Alcohol-Related Disorders --- Prescription Drug Misuse --- Abuse of substances --- Chemical dependence --- Chemical dependency --- Substance addiction --- Substance dependence --- Substance-related disorders --- Substance use disorders --- Illicit Drugs --- Codependency, Psychological --- Chemical Dependence --- Substance Use --- Chemical Dependences --- Dependence, Chemical --- Dependences, Chemical --- Substance Uses --- Use, Substance --- Substance Related Disorder --- Disorder, Substance Related --- Disorders, Substance Related --- Related Disorder, Substance --- Related Disorders, Substance

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Developing Countries --- Substance-Related Disorders --- Public Health --- Mental Disorders --- Psychiatry and Psychology --- International Cooperation --- Medicine --- Diseases --- Health Occupations --- Internationality --- Disciplines and Occupations --- Social Sciences --- Anthropology, Education, Sociology and Social Phenomena --- Mental Illness Prevention --- Health & Biological Sciences --- Science, Social --- Sciences, Social --- Social Science --- Globalization --- International Aspects --- International Perspectives --- International Relations --- Multinational Aspects --- Multinational Perspectives --- Aspect, International --- Aspect, Multinational --- Aspects, International --- Aspects, Multinational --- International Aspect --- International Perspective --- Multinational Aspect --- Multinational Perspective --- Perspective, International --- Perspective, Multinational --- Perspectives, International --- Perspectives, Multinational --- Relations, International --- Health Professions --- Health Occupation --- Health Profession --- Occupation, Health --- Occupations, Health --- Profession, Health --- Professions, Health --- Medical Specialities --- Medical Specialties --- Medical Specialty --- Specialities, Medical --- Specialties, Medical --- Specialty, Medical --- Medical Speciality --- Speciality, Medical --- Treaties --- Foreign Aid --- Aid, Foreign --- Cooperation, International --- Treaty --- Behavior Disorders --- Diagnosis, Psychiatric --- Mental Disorders, Severe --- Psychiatric Diagnosis --- Disorder, Mental --- Disorder, Severe Mental --- Disorders, Behavior --- Disorders, Mental --- Disorders, Severe Mental --- Mental Disorder --- Mental Disorder, Severe --- Severe Mental Disorder --- Severe Mental Disorders --- Environment, Preventive Medicine & Public Health --- Environment, Preventive Medicine and Public Health --- Health, Public --- Substance Addiction --- Drug Abuse --- Drug Addiction --- Drug Dependence --- Drug Habituation --- Drug Use Disorders --- Organic Mental Disorders, Substance-Induced --- Substance Abuse --- Substance Dependence --- Substance Use Disorders --- Abuse, Drug --- Abuse, Substance --- Abuses, Substance --- Addiction, Drug --- Addiction, Substance --- Dependence, Drug --- Dependence, Substance --- Disorder, Drug Use --- Disorder, Substance Use --- Drug Use Disorder --- Habituation, Drug --- Organic Mental Disorders, Substance Induced --- Substance Abuses --- Substance Use Disorder --- Developing Nations --- Least Developed Countries --- Less-Developed Nations --- Third-World Nations --- Under-Developed Nations --- Less-Developed Countries --- Third-World Countries --- Under-Developed Countries --- Countries, Developing --- Countries, Least Developed --- Countries, Less-Developed --- Countries, Third-World --- Countries, Under-Developed --- Country, Developing --- Country, Least Developed --- Country, Less-Developed --- Country, Third-World --- Country, Under-Developed --- Developed Countries, Least --- Developed Country, Least --- Developing Country --- Developing Nation --- Least Developed Country --- Less Developed Countries --- Less Developed Nations --- Less-Developed Country --- Less-Developed Nation --- Nation, Less-Developed --- Nation, Third-World --- Nation, Under-Developed --- Nations, Developing --- Nations, Less-Developed --- Nations, Third-World --- Nations, Under-Developed --- Third World Countries --- Third World Nations --- Third-World Country --- Third-World Nation --- Under Developed Countries --- Under Developed Nations --- Under-Developed Country --- Under-Developed Nation --- Mental Disorders. --- Developing Countries. --- Public Health. --- Substance-Related Disorders. --- Prescription Drug Abuse --- Abuse, Prescription Drug --- Drug Abuse, Prescription --- Drug and Narcotic Control --- Disruptive, Impulse Control, and Conduct Disorders --- Psychoses, Alcoholic --- Social Problems --- Street Drugs --- Designer Drugs --- Behavior, Addictive --- Codependency (Psychology) --- Alcohol-Related Disorders --- Prescription Drug Misuse --- Community Health --- Health, Community --- Preventive Medicine --- Education, Public Health Professional --- Mentally Ill Persons --- Illicit Drugs --- Codependency, Psychological --- Psychiatric Diseases --- Psychiatric Disorders --- Psychiatric Illness --- Psychiatric Disease --- Psychiatric Disorder --- Psychiatric Illnesses --- Chemical Dependence --- Substance Use --- Chemical Dependences --- Dependence, Chemical --- Dependences, Chemical --- Substance Uses --- Use, Substance --- Mental Illness --- Illness, Mental --- Mental Illnesses --- Substance Related Disorder --- Disorder, Substance Related --- Disorders, Substance Related --- Related Disorder, Substance --- Related Disorders, Substance --- LMICs --- Low Income Countries --- Low and Middle Income Countries --- Lower-Middle-Income Country --- Middle Income Countries --- Countries, Middle Income --- Country, Low Income --- Country, Lower-Middle-Income 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The past thirty years have witnessed a revolution in the science of addiction, yet we still rely on outdated methods of treatment. Expensive new programs for managing addiction are also flourishing, but since they are not based in science, they offer little benefit to people who cannot afford to lose money or faith in their recovery.Clarifying the cutting-edge science of addiction for both practitioners and general readers, The Thirteenth Step pairs stories of real patients with explanations of key concepts relating to their illness. A police chief who disappears on the job illustrates the process through which a drug can trigger the brain circuits mediating relapse. One person's effort to find a burrito shack in a foreign city illuminates the reward prediction error signaled by the brain chemical dopamine. With these examples and more, this volume paints a vivid, readable portrait of drug seeking, escalation, and other aspects of addiction and suggests science-based treatments that promise to improve troubling relapse rates. Merging science and human experience, The Thirteenth Step offers compassionate, valuable answers to anyone who hopes for a better handle on a confounding disease.

Behavior, Addictive -- Metabolism. --- Brain -- Physiopathology. --- Substance-Related disorders -- Therapy. --- Metabolic Phenomena --- Compulsive Behavior --- Alcohol-Related Disorders --- Central Nervous System --- Pharmacology --- Diseases --- Genetics --- Mental Disorders --- Psychiatry and Psychology --- Biology --- Biological Science Disciplines --- Health Occupations --- Phenomena and Processes --- Impulsive Behavior --- Nervous System --- Behavior --- Anatomy --- Disciplines and Occupations --- Natural Science Disciplines --- Behavior and Behavior Mechanisms --- Pharmacogenetics --- Alcoholism --- Substance-Related Disorders --- Behavior, Addictive --- Brain --- Metabolism --- Psychiatry --- Health & Biological Sciences --- Substance Abuse Disorders --- Metabolic Phenomenon --- Metabolic Process --- Metabolism Concepts --- Metabolism Phenomena --- Process, Metabolic --- Processes, Metabolic --- Anabolism --- Catabolism --- Metabolic Concepts --- Metabolic Processes --- Concept, Metabolic --- Concept, Metabolism --- Concepts, Metabolic --- Concepts, Metabolism --- Metabolic Concept --- Metabolism Concept --- Phenomena, Metabolic --- Phenomena, Metabolism --- Phenomenon, Metabolic --- Encephalon --- Addictive Behavior --- Addictive Behaviors --- Behaviors, Addictive --- Prescription Drug Abuse --- Substance Addiction --- Chemical Dependence --- Drug Abuse --- Drug Addiction --- Drug Dependence --- Drug Habituation --- Drug Use Disorders --- Organic Mental Disorders, Substance-Induced --- Substance Abuse --- Substance Dependence --- Substance Use --- Substance Use Disorders --- Abuse, Drug --- Abuse, Prescription Drug --- Abuse, Substance --- Addiction, Drug --- Addiction, Substance --- Chemical Dependences --- Dependence, Chemical --- Dependence, Drug --- Dependence, Substance --- Dependences, Chemical --- Disorder, Drug Use --- Disorder, Substance Use --- Drug Abuse, Prescription --- Drug Use Disorder --- Habituation, Drug --- Organic Mental Disorders, Substance Induced --- Substance Abuses --- Substance Use Disorder --- Substance Uses --- Use, Substance --- Drug and Narcotic Control --- Disruptive, Impulse Control, and Conduct Disorders --- Psychoses, Alcoholic --- Social Problems --- Illicit Drugs --- Designer Drugs --- Codependency, Psychological --- Prescription Drug Misuse --- Alcohol Addiction --- Alcohol Dependence --- Alcohol Use Disorder --- Alcohol Abuse --- Alcoholic Intoxication, Chronic --- Ethanol Abuse --- Abuse, Alcohol --- Abuse, Ethanol --- Addiction, Alcohol --- Alcohol Use Disorders --- Chronic Alcoholic Intoxication --- Dependence, Alcohol --- Intoxication, Chronic Alcoholic --- Use Disorders, Alcohol --- Blood Alcohol Content --- Alcohol Drinking --- Fetal Alcohol Spectrum Disorders --- Genetic Structures --- Genetic Phenomena --- Pharmacogenomics --- Pharmacogenomic Variants --- Drug Resistance --- Toxicology --- Precision Medicine --- Behavior And Behavior Mechanism --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Pharmacologies --- Pharmaceutical Preparations --- Anatomies --- Acceptance Process --- Acceptance Processes --- Behaviors --- Process, Acceptance --- Processes, Acceptance --- Nervous Systems --- System, Nervous --- Systems, Nervous --- Impulsivity --- Behavior, Impulsive --- Behaviors, Impulsive --- Impulsive Behaviors --- Impulsivities --- Delay Discounting --- Health Professions --- Health Occupation --- Health Profession --- Profession, Health --- Professions, Health --- Occupations --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Behavior Disorders --- Diagnosis, Psychiatric --- Mental Disorders, Severe --- Psychiatric Diagnosis --- Mental Illness --- Psychiatric Diseases --- Psychiatric Disorders --- Psychiatric Illness --- Illness, Mental --- Mental Disorder --- Mental Disorder, Severe --- Mental Illnesses --- Psychiatric Disease --- Psychiatric Disorder --- Psychiatric Illnesses --- Severe Mental Disorder --- Severe Mental Disorders --- Mentally Ill Persons --- Cerebrospinal Axis --- Axi, Cerebrospinal --- Axis, Cerebrospinal --- Central Nervous Systems --- Cerebrospinal Axi --- Nervous System, Central --- Nervous Systems, Central --- Systems, Central Nervous --- Alcohol Problem --- Alcohol Problems --- Alcohol Related Disorders --- Alcohol-Related Disorder --- Disorder, Alcohol-Related --- Behavior, Compulsive --- Behaviors, Compulsive --- Compulsive Behaviors --- pharmacology --- Substance abuse --- Neurosciences. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Treatment. --- Effect of drugs on.