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The Palgrave Handbook of Philosophical Methods
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ISBN: 1786846993 1137344555 Year: 2015 Publisher: London : Palgrave Macmillan UK : Imprint: Palgrave Macmillan,

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This Handbook contains twenty-six original and substantive papers examining a wide selection of philosophical methods. Drawing upon an international range of leading contributors, it will help shape future debates about how philosophy should be done. The papers will be of particular interest to researchers and high-level undergraduates.


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Aging Research - Methodological Issues
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ISBN: 3319183230 Year: 2015 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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This book reviews classical epidemiological and clinical research studies, with a focus on aging. Chapters cover methodological topics like the scientific method, ethics, and the consequences of certain exclusion criteria, and the work includes a look at clinical concepts like multimorbidity, frailty and functionality. The authors reveal the issues and challenges for researchers of age and aging, and also consider the translation of scientific knowledge, from basic to clinical, and from clinical to public policies of social and health care.   The focus on aging is what gives this book its valuable perspective on research methodology. All authors have considerable experience in aging, geriatrics or gerontology, and each chapter includes both a theoretical framework and practical examples of studies in aging. Readers will discover study designs that are reviewed for basic structure, main flaws and advantages, and are analyzed for specific conditions and variables regarding aging. This text is suited to both health care professionals caring for older adults, and researchers who are new to research in aging. It is relevant across the disciplines, including medicine, psychology, social sciences and dentistry, and it supports learning with graphs and figures.


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Regulating Securitized Products : A Post Crisis Guide
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ISBN: 1137497955 Year: 2015 Publisher: London : Palgrave Macmillan UK : Imprint: Palgrave Macmillan,

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Securitization regulation remains, in the eyes of investors, banks, businesses, bureaucrats and politicians, one of the remaining unsolved puzzles of the post-Global Financial Crisis landscape. This book describes the key features of securitization, including the most common structures and their uses as well as the motivations of the participants in these markets. Important historical moments and case studies are frequently used to illustrate critical issues in the design and enforcement of regulation for securitized products. This work is intended to contextualize and contribute to the highly specialized debates between policymakers, regulators and the regulated financial intermediaries, setting out an agenda for discussion as well as providing some strongly held views on possible solutions. Written by an industry insider with over 20 years' experience in the markets, this book considers regulatory tools from all sides while avoiding common biases. It is a valuable source for not only regulators and policymakers, but also educators, students and researchers in financial regulation, financial engineering and investment management.


Book
Heat Shock Protein-Based Therapies
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ISBN: 9783319172118 3319172107 9783319172101 3319172115 Year: 2015 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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  The book Heat Shock Protein-Based Therapies provides the most up-to-date review on new heat shock protein-based mechanisms used in the therapy and treatment of various human disorders and diseases, including cancer, muscular atrophy, neurodegenerative disorders (Alzheimer's Disease, Multiple Sclerosis) and infectious diseases (HIV, periodontal disease). Written by leaders in the field of heat shock protein research, the chapters systematically and in a step wise fashion takes the reader through the fascinating sequence of events by which mechanisms dependent on heat shock proteins are targeted. The chapters also provide answers as to HSP biological significance to the host. This book is a must read for graduate and postgraduates in the field of Drug Development, Biotechnology, Pharmaceutical Industry, Phytomedicine, Biology (plant and mammal), Biochemistry (pro- and eukaryotic), Oncology, Immunology, Microbiology, Exercise Medicine, Physiology, Inflammatory diseases, Autoimmunity, Pharmacology and Pathology.


Book
Machine Learning in Medicine - a Complete Overview
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ISBN: 9783319151953 3319151940 9783319151946 3319151959 Year: 2015 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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The current book is the first publication of a complete overview of machine learning methodologies for the medical and health sector. It was written as a training companion, and as a must-read, not only for physicians and students, but also for any one involved in the process and progress of health and health care. In eighty chapters eighty different machine learning methodologies are reviewed, in combination with data examples for self-assessment. Each chapter can be studied without the need to consult other chapters. The amount of data stored in the world's databases doubles every 20 months, and clinicians, familiar with traditional statistical methods, are at a loss to analyze them. Traditional methods have, indeed, difficulty to identify outliers in large datasets, and to find patterns in big data and data with multiple exposure / outcome variables. In addition, analysis-rules for surveys and questionnaires, which are currently common methods of data collection, are, essentially, missing. Fortunately, the new discipline, machine learning, is able to cover all of these limitations. So far medical professionals have been rather reluctant to use machine learning. Also, in the field of diagnosis making, few doctors may want a computer checking them, are interested in collaboration with a computer or with computer engineers. Adequate health and health care will, however, soon be impossible without proper data supervision from modern machine learning methodologies like cluster models, neural networks, and other data mining methodologies. Each chapter starts with purposes and scientific questions. Then, step-by-step analyses, using data examples, are given. Finally, a paragraph with conclusion, and references to the corresponding sites of three introductory textbooks, previously written by the same authors, is given.


Book
Essays on Research Methodology
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ISBN: 9788132222149 813222213X 9788132222132 8132222148 Year: 2015 Publisher: New Delhi : Springer India : Imprint: Springer,

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The book presents a collection of essays addressing a perceived need for persistent and logical thinking, critical reasoning, rigor and relevance on the part of researchers pursuing their doctorates. Accordingly, eminent experts have come together to consider these significant aspects of the research process, which result in different knowledge claims in different fields or subject areas. An attempt has been made to find a common denominator across diverse management disciplines, so that the broadest range of researchers can benefit from the book. The topics have been carefully chosen to cover problem formulation, contextualizing, soft & hard modeling, qualitative and quantitative analysis and ethical issues, in addition to the design of experiments and survey-based research. The distinguishing feature of this book is that it recognizes the diverse backgrounds of scholars from different interdisciplinary areas as well as their varying needs with regard to modeling, observations, measurements, aggregation, data analyses, etc. After all, researchers are expected to deepen our understanding, expand on existing information, introduce fresh insights, present new evidence and/or disprove accepted theories, hypotheses etc. More importantly, the book cautions against the over-reliance on software packages and mechanical interpretation of results based on the size, sign and significance of the coefficients obtained. Instead, the focus is on the underlying theories, hypotheses and relationships, and on establishing new ones. In doing so, due care is taken to clearly enunciate what exactly constitutes a knowledge claim and what is methodology as distinct from methods, tools and techniques.  .


Book
Water Stress in Biological, Chemical, Pharmaceutical and Food Systems
Authors: --- --- --- --- --- et al.
ISBN: 9781493925780 1493925776 9781493925773 1493925784 Year: 2015 Publisher: New York, NY : Springer New York : Imprint: Springer,

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Water Stress Management contains the invited lectures and selected oral and poster presentations of the 11th International Symposium on the Properties of Water (ISOPOW), which was held in Queretaro, Mexico 5-9 September 2010. The text provides a holistic description and discussion of state-of-the-art topics on the role of water in Biological, Chemical, Pharmaceutical, and Food systems within a frame of an integrated approach and future trends on the subject. Different points-of-view about the state of water and phase transitions in a variety of substrates are presented. ISOPOW is a non-profit scientific organization whose activities aim at progressing the understanding of the properties of water in food and related biological systems, and the exploitation of this understanding in improved raw materials, products and processes in the food, agrofood or related industries. The first Symposium was organized in Glasgow , Scotland in 1974. Since then, ISOPOW meetings have promoted the exchange of knowledge between scientists involved in the study of food materials and scientists interested in water from a more basic point of view and the dialogue between academic and industrial scientists/technologists.


Book
Management and Leadership – A Guide for Clinical Professionals
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ISBN: 9783319115269 3319115251 9783319115252 331911526X Year: 2015 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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This book contains a series of chapters on various aspects of management and leadership in a health care organisation, written by some of the most experienced authors from around the world. It provides an understanding of basic management and leadership skills that are essential for clinical as well as non-clinical staff in a health care organisation, in a simple and clear fashion. Management and leadership skills are critical for developing a successful and productive career, and achieving organisational goals. The journey towards a successful career starts with a thorough preparation for an interview. The topics covered in this book range from preparing for an interview, the art of negotiation and handling difficult behaviour, to clinical leadership, evidence based management, mentorship, and conflict resolution. The significance of formal training in management and leadership skills can not be overemphasised considering the increasing focus on developing clinicians as leaders (“Clinical leadership”) at the work place. Unfortunately not enough attention is paid to such training during the early part of career of the clinical (e.g. doctors, nurses) and non-clinical staff. With its simple and reader friendly approach this unique and concise book will be useful for all staff working in a health care organisation irrespective of their faculty, position, and stage in career in becoming successful consultants, managers, supervisors, and leaders. Key features and contents: ·     Interview skills ·     The art of negotiation, handling difficult behaviour, and facing the media ·     Quality improvement ·     Risk management ·     Occupational health and safety ·     Performance appraisals and assessment ·     Conflict resolution ·     Clinical leadership ·     Evidence based management ·     How to break a bad news.


Book
The Calculus of Life : Towards a Theory of Life
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ISBN: 9783319169705 3319169696 9783319169699 331916970X Year: 2015 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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This book explores the exciting world of theoretical biology and is divided into three sections. The first section examines the roles played by renowned scientists such as Jacob, Monod, Rosen, Turing, von Bertalanffy, Waddington and Woodger in developing the field of theoretical biology. The second section, aided with numerous examples, supports the idea that logic and computing are suitable formal languages to describe and understand biological phenomena. The third and final section is, without doubt, the most intellectually challenging and endeavors to show the possible paths we could take to compute a cell - the basic unit of life - or the conditions required for a predictive theory of biological evolution; ultimately, a theory of life in the light of modern Systems Biology. The work aims to show that modern biology is closer than ever to making Goethe's dream come true and that we have reached a point where synthetic and analytical traditions converge to shed light on the living being as a whole.


Book
Scientific Peer Reviewing : Practical Hints and Best Practices
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ISBN: 3319250833 3319250841 Year: 2015 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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This booklet provides a practical introduction to the practice of peer reviewing. Although it mainly focuses on paper reviewing for scientific events in computer science and business informatics, many of the principles, tips, tricks and examples can also be applied to journal reviewing and other scientific domains. Some can also be used when reviewing proposals for research projects or grants. In addition, many aspects of the book will benefit authors of scientific papers, who will gain deeper insights into how papers are reviewed and hence what to pay attention to when writing their own papers. The book is divided into three chapters, the first of which presents a brief overview of why peer reviewing is considered to be an important quality control instrument for scientific papers. In turn, the second chapter elaborates on the main principles a good reviewer should adhere to, including the most important aspects of personal attitude s/he should pay attention to when writing his/her review. Lastly, the third chapter features a series of (anonymized) real life examples of actual reviewing practice, thus illustrating practical tips and tricks regarding the most common “do’s” and “don’ts” of peer reviewing.The book offers a structured introduction and practical reference guide, including good and bad examples, for junior researchers in computer science and business informatics in particular, as well as for anyone interested in peer reviewing in general.

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