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Throughout history, arsenic has been used as an effective and lethal poison. Today, arsenic continues to present a real threat to human health all over the world, as it contaminates groundwater and food supplies. Handbook of Arsenic Toxicology presents the latest findings on arsenic, its chemistry, its sources and its acute and chronic effects on the environment and human health. The book takes readings systematically through the target organs, before detailing current preventative and counter measures. This reference enables readers to effectively assess the risks related to arsenic, and provide a comprehensive look at arsenic exposure, toxicity and toxicity prevention. Brings together current findings on the effects of arsenic on the environment and human health Includes state-of-the-art techniques in arsenic toxicokinetics, speciation and molecular mechanisms Provides all the information needed for effective risk assessment, prevention and countermeasure.

MEDICAL --- Toxicology --- Arsenic --- Metalloids --- Epidemiologic Measurements --- Risk Management --- Elements --- Environmental Pollution --- Risk --- Probability --- Inorganic Chemicals --- Public Health --- Organization and Administration --- Statistics as Topic --- Environment and Public Health --- Chemicals and Drugs --- Health Services Administration --- Health Care --- Health Care Evaluation Mechanisms --- Epidemiologic Methods --- Investigative Techniques --- Quality of Health Care --- Health Care Quality, Access, and Evaluation --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Environmental Exposure --- Risk Assessment --- Health & Biological Sciences --- Toxicology & Public Health --- Environmental aspects --- Toxicology. --- Arseniasis --- Arsenic poisoning --- Arsenicism

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PSYCHOLOGY --- Clinical Psychology --- Affective disorders --- Affective Disorders, Psychotic --- Evaluation Studies as Topic --- Epidemiologic Study Characteristics as Topic --- Mental Disorders --- Psychiatry and Psychology --- Epidemiologic Methods --- Health Care Evaluation Mechanisms --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Quality of Health Care --- Public Health --- Environment and Public Health --- Health Care Quality, Access, and Evaluation --- Health Care --- Clinical Trials as Topic --- Mood Disorders --- Bipolar Disorder --- Psychiatry --- Health & Biological Sciences --- Psychiatric Disorders, Individual --- Treatment --- Affective disorders. --- Disorders, Affective --- Mood disorders --- Psychology, Pathological --- Clinical Trials as Topic. --- therapy. --- Bipolar Disorder ##x therapy. --- Clinical Trial as Topic --- Clinical Protocols --- Drug Evaluation --- Drugs, Investigational --- Clinical Trials Data Monitoring Committees --- Therapies, Investigational

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This book explains the key steps in planning and executing diagnostic test accuracy studies in dementia, with clear explanations of difficulties and pitfalls, and with jargon clearly explained. The emphasis is on pragmatic diagnostic test accuracy studies which can be integrated into day-to-day clinical practice. The book is based on the author’s experience over more than 10 years, which has resulted in the publication of many diagnostic test accuracy studies.   The text is structured as for a research publication on a diagnostic test accuracy study (Introduction, Methods, Results, Discussion), with a final chapter on Future Prospects. Each of the chapters is devoted to a practical and structured overview of each of these steps in performing and writing up such a study.    Diagnostic Test Accuracy Studies in Dementia: A Pragmatic Approach is aimed at any clinician with an interest in dementia disorders: old age psychiatrists, geriatricians, neurologists, neuropsychologists and primary care physicians, as well as other professions allied to medicine. The book is also of interest to any clinician/researcher with an interest in diagnostic test accuracy studies.

Medicine & Public Health. --- Neurology. --- Psychiatry. --- Geriatrics/Gerontology. --- Neuropsychology. --- Medicine. --- Geriatrics. --- Psychology, clinical. --- Médecine --- Gériatrie --- Neurologie --- Psychiatrie --- Mathematical Concepts --- Statistics as Topic --- Delirium, Dementia, Amnestic, Cognitive Disorders --- Epidemiologic Research Design --- Diagnosis --- Brain Diseases --- Epidemiologic Methods --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Phenomena and Processes --- Mental Disorders --- Central Nervous System Diseases --- Health Care Evaluation Mechanisms --- Investigative Techniques --- Public Health --- Quality of Health Care --- Psychiatry and Psychology --- Nervous System Diseases --- Health Care Quality, Access, and Evaluation --- Environment and Public Health --- Diseases --- Health Care --- Diagnostic Techniques and Procedures --- Dementia --- Sensitivity and Specificity --- Psychiatry --- Health & Biological Sciences --- Psychiatric Disorders, Individual --- Alzheimer's disease --- Cognition disorders. --- Diagnosis. --- Cognitive disorders --- Aphrenia --- Aphronesia --- Athymia --- Dementias --- Brain --- Neurobehavioral disorders --- Psychoses --- Psychology, Pathological --- Medicine --- Gerontology --- Older people --- Nervous system --- Neuropsychiatry --- Medicine and psychology --- Mental health --- Health and hygiene --- Neurology . --- Neurophysiology --- Psychophysiology

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The U.S. Air Force, wanting to gain greater insight into the well-being of its members who have sustained mental or physical injuries in combat or combat-related situations, including their quality of life and the challenges they will confront in their reintegration following separation or retirement, asked the RAND Corporation for assistance in gauging the current status of the Air Force's wounded warriors, including their use of and satisfaction with Air Force programs designed to serve them. This report presents the baseline findings from a longitudinal analysis of enrollees in the Air Force Wounded Warrior (AFW2) program who were receiving benefits or undergoing evaluation to receive benefits, the majority of whom had a primary administrative diagnosis of post-traumatic stress disorder (PTSD). A high proportion of the Airmen in the sample screened positive for PTSD (roughly 78 percent) and major depressive disorder (MDD) (roughly 75 percent); 69 percent screened positive for both. Although more than 90 percent of those in the sample who screened positive for PTSD or MDD were receiving treatment, about half indicated that there was at least one instance during the past year in which they desired mental health treatment but did not receive it. Participants reported concerns about stigma, confidentiality, and the quality of available treatment as barriers to receiving mental health care, though the current data do not link these concerns to a particular treatment setting. About 10 percent of Airmen reported a financial situation that could be considered as living in poverty based on U.S. Department of Health and Human Services' poverty guidelines. Similarly, close to 15 percent of those in the labor force could be considered unemployed. Reserve and National Guard Airmen evidenced heightened challenges across examined domains. Respondents were overall satisfied with the services they received from the AFW2 and Air Force Recovery Care Coordinator programs

Veteran reintegration --- Medical care --- Afghan War, 2001 --- -Iraq War, 2003-2011 --- Disabled veterans --- Veterans --- Homelessness --- Social surveys --- Health Surveys --- Disabled Persons --- Veterans Health --- Wounds and Injuries --- Data Collection --- Health --- Persons --- Diseases --- Named Groups --- Epidemiologic Methods --- Health Care Evaluation Mechanisms --- Population Characteristics --- Investigative Techniques --- Public Health --- Health Care --- Quality of Health Care --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Environment and Public Health --- Health Care Quality, Access, and Evaluation --- Military Administration --- Military & Naval Science --- Law, Politics & Government --- Needs assessment --- Services for --- Social conditions --- Mental health --- Employment --- Healthcare Quality, Access, and Evaluation --- Quality of Care --- Quality of Healthcare --- Care Qualities --- Care Quality --- Health Care Quality --- Healthcare Quality --- Community-Based Distribution --- Contraceptive Distribution --- Delivery of Healthcare --- Dental Care Delivery --- Distribution, Non-Clinical --- Distribution, Nonclinical --- Distributional Activities --- Healthcare --- Healthcare Delivery --- Healthcare Systems --- Non-Clinical Distribution --- Nonclinical Distribution --- Delivery of Dental Care --- Health Care Delivery --- Health Care Systems --- Activities, Distributional --- Activity, Distributional --- Care, Health --- Community Based Distribution --- Community-Based Distributions --- Contraceptive Distributions --- Deliveries, Healthcare --- Delivery, Dental Care --- Delivery, Health Care --- Delivery, Healthcare --- Distribution, Community-Based --- Distribution, Contraceptive --- Distribution, Non Clinical --- Distributional Activity --- Distributions, Community-Based --- Distributions, Contraceptive --- Distributions, Non-Clinical --- Distributions, Nonclinical --- Health Care System --- Healthcare Deliveries --- Healthcare System --- Non Clinical Distribution --- Non-Clinical Distributions --- Nonclinical Distributions --- System, Health Care --- System, Healthcare --- Systems, Health Care --- Systems, Healthcare --- Environment, Preventive Medicine & Public Health --- Environment, Preventive Medicine and Public Health --- Health, Public --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Population Heterogeneity --- Population Statistics --- Characteristic, Population --- Characteristics, Population --- Heterogeneity, Population --- Population Characteristic --- Statistics, Population --- Healthcare Evaluation Mechanisms --- Evaluation Mechanism, Healthcare --- Evaluation Mechanisms, Healthcare --- Healthcare Evaluation Mechanism --- Mechanism, Healthcare Evaluation --- Mechanisms, Healthcare Evaluation --- Epidemiologic Method --- Epidemiological Methods --- Methods, Epidemiologic --- Epidemiological Method --- Method, Epidemiologic --- Method, Epidemiological --- Methods, Epidemiological --- Epidemiology --- Person --- Normalcy --- Normality --- Normalities --- Data Aggregation --- Data Collection Methods --- Dual Data Collection --- Aggregation, Data --- Collection Method, Data --- Collection Methods, Data --- Collection, Data --- Collection, Dual Data --- Data Collection Method --- Method, Data Collection --- Methods, Data Collection --- Injuries and Wounds --- Injuries, Wounds --- Research-Related Injuries --- Wounds --- Wounds and Injury --- Wounds, Injury --- Injuries --- Trauma --- Injuries, Research-Related --- Injury --- Injury and Wounds --- Injury, Research-Related --- Research Related Injuries --- Research-Related Injury --- Traumas --- Wound --- Health, Veterans --- Veteran --- Physically Disabled --- Handicapped --- People with Disabilities --- Persons with Disabilities --- Physically Challenged --- Physically Handicapped --- Disabilities, People with --- Disabilities, Persons with --- Disability, Persons with --- Disabled Person --- Disabled, Physically --- Handicapped, Physically --- People with Disability --- Person, Disabled --- Persons with Disability --- Persons, Disabled --- Abortion Surveys --- Abortion Survey --- Health Survey --- Survey, Abortion --- Survey, Health --- Surveys, Abortion --- Surveys, Health --- Disabled sailors --- Disabled soldiers --- Service-disabled veterans --- Veterans, Disabled --- Anglo-American Invasion of Iraq, 2003-2011 --- Dawn, Operation New, 2010-2011 --- Gulf War II, 2003-2011 --- Iraqi Freedom, Operation, 2003-2010 --- New Dawn, Operation, 2010-2011 --- Operation Iraqi Freedom, 2003-2010 --- Operation New Dawn, 2010-2011 --- Operation Telic, 2003-2011 --- Persian Gulf War, 2003-2011 --- Telic, Operation, 2003-2011 --- Delivery of health care --- Delivery of medical care --- Health care --- Health care delivery --- Health services --- Medical and health care industry --- Medical services --- Personal health services --- Community reintegration, Veteran --- Post-deployment reintegration --- Reintegration, Veteran --- Veteran-community reintegration --- methods --- Reintegration --- Pharmacy Audit --- Audit, Pharmacy --- Pharmacy Audits --- Community Health --- Health, Community --- Preventive Medicine --- Education, Public Health Professional --- Medical History Taking --- Empirical Research --- First Aid --- Traumatology --- War Exposure --- Military Personnel --- Military Family --- Rehabilitation Research --- Bedridden Persons --- Immobilization --- Sports for Persons with Disabilities --- Health Services for Persons with Disabilities --- People with disabilities --- War on Terrorism, 2001-2009 --- Operation Enduring Freedom, 2001 --- -War on Terrorism, 2001-2009 --- Public health --- Resocialization --- Sanitary Surveys, Water Supply --- -Operation Enduring Freedom, 2001 --- Afghan War, 2001-2021 --- Iraq War, 2003-2011 --- United States. --- Airmen --- AF (Air force) --- Air Force (U.S.) --- U.S.A.F. (Air force) --- United States Air Force --- US Air Force --- USAF (Air force) --- Military Health --- Health Surveys. --- Persons with Disabilities. --- Veterans Health. --- Health Care Evaluation Mechanisms. --- Environment and Public Health. --- Health Care Quality, Access, and Evaluation.

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Comprehensively covers protein subcellular localization from single-label prediction to multi-label prediction, and includes prediction strategies for virus, plant, and eukaryote species. Three machine learning tools are introduced to improve classification refinement, feature extraction, and dimensionality reduction.

Artificial intelligence. --- Probability. --- Protein transport. --- Statistics as Topic --- Computing Methodologies --- Biological Transport --- Mathematical Concepts --- Phenomena and Processes --- Health Care Evaluation Mechanisms --- Information Science --- Epidemiologic Methods --- Metabolism --- Public Health --- Investigative Techniques --- Metabolic Phenomena --- Quality of Health Care --- Health Care Quality, Access, and Evaluation --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Environment and Public Health --- Health Care --- Probability --- Protein Transport --- Artificial Intelligence --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Computational Intelligence --- AI (Artificial Intelligence) --- Computer Reasoning --- Computer Vision Systems --- Knowledge Acquisition (Computer) --- Knowledge Representation (Computer) --- Machine Intelligence --- Acquisition, Knowledge (Computer) --- Computer Vision System --- Intelligence, Artificial --- Intelligence, Computational --- Intelligence, Machine --- Knowledge Representations (Computer) --- Reasoning, Computer --- Representation, Knowledge (Computer) --- System, Computer Vision --- Systems, Computer Vision --- Vision System, Computer --- Vision Systems, Computer --- Heuristics --- Protein Localization Processes, Cellular --- Protein Sorting --- Protein Trafficking --- Cellular Protein Targeting --- Gated Protein Transport --- Protein Targeting, Cellular --- Protein Translocation --- Transmembrane Protein Transport --- Vesicular Protein Transport --- Protein Transport, Gated --- Protein Transport, Transmembrane --- Protein Transport, Vesicular --- Traffickings, Protein --- Protein Sorting Signals --- Vesicular Transport Proteins --- Probabilities --- Community-Based Distribution --- Contraceptive Distribution --- Delivery of Healthcare --- Dental Care Delivery --- Distribution, Non-Clinical --- Distribution, Nonclinical --- Distributional Activities --- Healthcare --- Healthcare Delivery --- Healthcare Systems --- Non-Clinical Distribution --- Nonclinical Distribution --- Delivery of Dental Care --- Health Care Delivery --- Health Care Systems --- Activities, Distributional --- Activity, Distributional --- Care, Health --- Community Based Distribution --- Community-Based Distributions --- Contraceptive Distributions --- Deliveries, Healthcare --- Delivery, Dental Care --- Delivery, Health Care --- Delivery, Healthcare --- Distribution, Community-Based --- Distribution, Contraceptive --- Distribution, Non Clinical --- Distributional Activity --- Distributions, Community-Based --- Distributions, Contraceptive --- Distributions, Non-Clinical --- Distributions, Nonclinical --- Health Care System --- Healthcare Deliveries --- Healthcare System --- Non Clinical Distribution --- Non-Clinical Distributions --- Nonclinical Distributions --- System, Health Care --- System, Healthcare --- Systems, Health Care --- Systems, Healthcare --- Healthcare Quality, Access, and Evaluation --- Pharmacy Audit --- Quality of Care --- Quality of Healthcare --- Audit, Pharmacy --- Care Quality --- Health Care Quality --- Healthcare Quality --- Pharmacy Audits --- Metabolic Phenomenon --- Metabolic Process --- Metabolism Concepts --- Metabolism Phenomena --- Process, Metabolic --- Processes, Metabolic --- Anabolism --- Catabolism --- Metabolic Concepts --- Metabolic Processes --- Concept, Metabolic --- Concept, Metabolism --- Concepts, Metabolic --- Concepts, Metabolism --- Metabolic Concept --- Metabolism Concept --- Phenomena, Metabolic --- Phenomena, Metabolism --- Phenomenon, Metabolic --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Community Health --- Environment, Preventive Medicine & Public Health --- Environment, Preventive Medicine and Public Health --- Health, Community --- Health, Public --- Preventive Medicine --- Education, Public Health Professional --- Epidemiologic Method --- Epidemiological Methods --- Methods, Epidemiologic --- Epidemiological Method --- Method, Epidemiologic --- Method, Epidemiological --- Methods, Epidemiological --- Epidemiology --- Information Sciences --- Science, Information --- Sciences, Information --- Healthcare Evaluation Mechanisms --- Evaluation Mechanism, Healthcare --- Evaluation Mechanisms, Healthcare --- Healthcare Evaluation Mechanism --- Mechanism, Healthcare Evaluation --- Mechanisms, Healthcare Evaluation --- Concept, Mathematical --- Concepts, Mathematical --- Mathematical Concept --- Biologic Transport --- Transport, Biological --- Transport, Biologic --- Transport Vesicles --- Membrane Transport Proteins --- High Performance Computing --- Methodologies, Computing --- Computing Methodology --- Computing, High Performance --- Methodology, Computing --- Performance Computing, High --- Area Analysis --- Estimation Technics --- Estimation Techniques --- Indirect Estimation Technics --- Indirect Estimation Techniques --- Multiple Classification Analysis --- Service Statistics --- Statistical Study --- Statistics, Service --- Tables and Charts as Topic --- Analyses, Area --- Analyses, Multiple Classification --- Area Analyses --- Classification Analyses, Multiple --- Classification Analysis, Multiple --- Estimation Technic, Indirect --- Estimation Technics, Indirect --- Estimation Technique --- Estimation Technique, Indirect --- Estimation Techniques, Indirect --- Indirect Estimation Technic --- Indirect Estimation Technique --- Multiple Classification Analyses --- Statistical Studies --- Studies, Statistical --- Study, Statistical --- Technic, Indirect Estimation --- Technics, Estimation --- Technics, Indirect Estimation --- Technique, Estimation --- Technique, Indirect Estimation --- Techniques, Estimation --- Techniques, Indirect Estimation --- methods --- Proteins --- Machine learning. --- Physiological transport --- Data processing. --- Learning, Machine --- Artificial intelligence --- Machine theory --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Bioinformatics. --- Computer Science. --- Proteomics.