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This practical clinical handbook reveals that sickle cell disease (SCD) is an increasingly common condition to manage in Europe and North America. SCD demands clinical expertise and experience as well as sensitivity to its social and cultural context. This book is designed to broaden readers’ knowledge in this challenging condition by describing the acute and long-term complications unique to SCD and that affect nearly every system of the body. Critically, it also details the significant recent advances in understanding the pathophysiology of SCD that are leading to novel treatment modalities. Sickle Cell Disease in Clinical Practice promotes higher quality care by outlining the clinical problems as they arise, and covering essential background information, including up-to-date research, and useful points to guide management. As such, the intended target audience is broad and includes general physicians, general practitioners, hematologists, pediatricians, emergency medicine physicians, surgeons, medical students, nurse specialists and commissioners.

Medicine & Public Health. --- Hematology. --- Pathology. --- Blood Transfusion Medicine. --- Medicine. --- Blood transfusion. --- Médecine --- Hématologie --- Pathologie --- Medicine --- Health & Biological Sciences --- Pathology --- Sickle cell anemia. --- Clinical medicine. --- Medicine, Clinical --- Drepanocytic anemia --- Meniscocytosis --- Sickle cell disease --- Blood hyperviscosity syndrome --- Hemoglobinopathy --- Hemolytic anemia --- Blood transfusion --- Blood transfusion therapy --- Hemotherapy --- Transfusion medicine --- Transfusion of blood --- Transfusion therapy --- Transfusion therapy, Blood --- Surgery --- Blood banks --- Blood groups --- Hospitals --- Transfusion-free surgery --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine, Preventive --- Haematology --- Internal medicine --- Blood --- Transfusion committees

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This book covers a wide array of hematologic problems commonly encountered in the daily practice of critical care and emergency medicine. Unfortunately, the symptoms and signs associated with underlying hematologic disorders are frequently rather unspecific and confounding; furthermore, the clinical course of patients admitted to intensive care units with such disorders can be fulminant, warranting prompt diagnosis. This book recognizes the importance of accurate and speedy interpretation of symptoms in that the text is symptom oriented rather than disease oriented. Put another way, the reader confronted with a particular clinical problem or symptom will be guided step by step to the possible underlying disorder(s). The scenarios considered include critical illness in patients with anemia, leukopenia, leukocytosis, abnormal platelet count, and severe transfusion reactions. For each circumstance, factors relevant to symptom interpretation are fully discussed. In addition, helpful diagnostic algorithms are presented in the form of flow charts that will assist in decision making regarding the need for further investigations. The closing chapter is devoted to the drug-induced hematologic disorders. Although the book is intended mainly for intensivists, other specialists will find much information of value for their daily practice.

Medicine & Public Health. --- Intensive / Critical Care Medicine. --- Hematology. --- Blood Transfusion Medicine. --- Internal Medicine. --- Pharmacology/Toxicology. --- Medicine. --- Toxicology. --- Critical care medicine. --- Internal medicine. --- Blood transfusion. --- Médecine --- Toxicologie --- Soins intensifs --- Médecine interne --- Hématologie --- Medicine --- Health & Biological Sciences --- Emergency Medicine --- Blood --- Diseases --- Complications. --- Haematology --- Pharmacology. --- Body fluids --- Fear of blood --- Internal medicine --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Medicine, Internal --- Blood transfusion --- Blood transfusion therapy --- Hemotherapy --- Transfusion medicine --- Transfusion of blood --- Transfusion therapy --- Transfusion therapy, Blood --- Surgery --- Blood banks --- Blood groups --- Hospitals --- Transfusion-free surgery --- Intensive care --- Intensive medicine --- Emergency medicine --- Intensive care units --- Toxicology --- Transfusion committees --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect