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"In order to better understand the critical issues pertaining to the concept of performance standards for laboratory animal use, the Institute for Laboratory Animal Research Roundtable on Science and Welfare in Laboratory Animal Use held a public workshop on April 20-21, 2015. The purpose of the workshop was to promote the appropriate and responsible care of animals in research, to provide a balanced and civil forum for discussion and collaboration, and to help build transparency and trust among stakeholders. Participants addressed the challenges of defining, developing, implementing, assessing, and validating performance standards to ensure "optimal practices, management, and operations." This report summarizes the presentations and discussions from the workshop"--Publisher's description.

Laboratory animals --- Animal welfare --- Animals, Experimental --- Animals, Laboratory --- Animals in research --- Experimental animals --- Lab animals --- Animal culture --- Laboratory organisms --- Working animals --- Animal experimentation --- United States.

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As autism is associated with many rare diseases, this extensive bench book examines how no one single model can be used; multiple organism models are needed, each one corresponding to one of the diseases or to one aspect of a disease. Split into five sections, Organism Models of Autism Spectrum Disorders explores selecting the good species for the specific disease, modeling autism spectrum disorders (ASD) at the brain level, studying communication and social interactions, using vertebrates or invertebrate models of ASD as defined by DSM-5R, as well as pursuing models of diseases associated with an increased incidence of ASDs. Written for the respected Neuromethods series, this detailed volume contains the kind of insight and useful, practical advice that ensures more successful results in the lab. Comprehensive and handy, Organism Models of Autism Spectrum Disorders will benefit psychiatrists and geneticists, as well as behavioral researchers who, realizing how important it is to improve their knowledge through more molecular approaches, are looking for the most suitable organisms.

Neurosciences. --- Neurology. --- Laboratory animals. --- Animal Models. --- Animals, Experimental --- Animals, Laboratory --- Animals in research --- Experimental animals --- Lab animals --- Animal culture --- Laboratory organisms --- Working animals --- Animal experimentation --- Medicine --- Nervous system --- Neuropsychiatry --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Diseases

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This volume provides current up-to-date protocols for preparing the ovary for various imaging techniques, genetic protocols for generating mutant clones, mosaic analysis and assessing cell death. Chapters address methods for performing genome wide gene expression analysis and bioinformatics for studies of RNA-protein interactions. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.   Authoritative and cutting-edge, Drosophila Oogenesis: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Cytology. --- Laboratory animals. --- Cell Biology. --- Animal Models. --- Animals, Experimental --- Animals, Laboratory --- Animals in research --- Experimental animals --- Lab animals --- Animal culture --- Laboratory organisms --- Working animals --- Animal experimentation --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists

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The aim of this volume is to provide a step-by-step guide for implementing a selection of novel techniques in the lab. Each protocol in this volume is presented as a standalone chapter, specifically geared towards addressing practical needs without presuming prior knowledge of the technique at hand. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.   Authoritative and practical, C. elegans: Methods and Applications, Second Edition aims to ensure successful results in the further study of this dynamic field.

Human genetics. --- Animal genetics. --- Laboratory animals. --- Human Genetics. --- Animal Genetics and Genomics. --- Animal Models. --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Animals, Experimental --- Animals, Laboratory --- Animals in research --- Experimental animals --- Lab animals --- Animal culture --- Laboratory organisms --- Working animals --- Animal experimentation

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"Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives--both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine--from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer."--Publisher's website.

Animal experimentation --- Laboratory animals. --- Medicine --- History. --- Research --- Health Workforce --- Animals, Experimental --- Animals, Laboratory --- Animals in research --- Experimental animals --- Lab animals --- Animal culture --- Laboratory organisms --- Working animals --- Experimentation on animals --- Zoopery --- Laboratory animals --- transplants --- animal experiments --- laboratory animals --- surgery --- cancer research --- history of medicine --- vaccination --- Rabies --- Thalidomide