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Corynebacterium diphtheriae is the classical etiological agent of diphtheria and the type strain of the genus Corynebacterium. While diphtheria of the respiratory tract became rare with the introduction of vaccination programs in industrialized countries, even today several thousand cases per year are reported to the World Health Organization. This shows that diphtheria is not completely eradicated and that reservoirs exist. The book summarizes the latest advances made in understanding C. diphtheriae and the closely related species Corynebacterium ulcerans and Corynebacterium pseudotuberculosis. Topics addressed are genomics of toxigenic corynebacteria, host-pathogen-interaction, detection, surveillance and treatment as well as application aspects.

Corynebacterium diphtheriae. --- Diphtheria toxin. --- Bacillus diphtheriae --- Klebs-Loeffler bacillus --- Medicine. --- Medical microbiology. --- Parasitology. --- Epidemiology. --- Bacteriology. --- Microbial genetics. --- Microbial genomics. --- Biomedicine. --- Medical Microbiology. --- Microbial Genetics and Genomics. --- Bacterial toxins --- Corynebacterium --- Microbiology. --- Medical parasitology. --- Genomics --- Microbial genetics --- Microorganisms --- Genetics --- Microbiology --- Human beings --- Human parasitology --- Medical sciences --- Parasitology --- Parasitic diseases --- Diseases --- Public health --- Microbial biology --- Biology --- Parasites

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Currently, there are tremendous advances being made in understanding the basic science of both the structure and function of botulinum neurotoxins. This knowledge is opening up opportunities in regard to both therapeutic uses and treatment and protection options for civil and bio-defense applications. This volume fully evaluates the status of neurotoxin research and exploitation. The book is a multi-authored collection of chapters written by the leading authorities responsible for the current scientific and clinical research that is advancing the understanding and exploitation of the neurotoxins, and is both up to date and authoritative.

Biology --- Health & Biological Sciences --- Biophysics --- Botulinum toxin. --- Botulinum toxin --- Molecular aspects. --- Research. --- Botox (Trademark) --- Botulin --- Botulinismus toxin --- Botulinum neurotoxin --- Botulinus toxin --- Clostridium botulinum toxin --- Medicine. --- Molecular biology. --- Pharmacology. --- Neurology. --- Biomedicine. --- Molecular Medicine. --- Pharmacology/Toxicology. --- Biomedicine general. --- Bacterial toxins --- Neurotoxic agents --- Toxicology. --- Medicine --- Nervous system --- Neuropsychiatry --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Diseases --- Toxicology --- Health Workforce --- Neurology . --- Biomedicine, general. --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biomolecules --- Systems biology --- Physiological effect --- Biomedical Research. --- Biological research --- Biomedical research