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With the significant medical role that human cytomegalovirus plays in human disease (from acute disease following primary infection, to chronic disease due to life-long viral persistence), the need to better understand human cytomegalovirus biology and pathogenesis is needed.  Human Cytomegaloviruses: Methods and Protocols is designed to be an inclusive document covering all of the techniques and approaches necessary to understand and study the pathobiology of human cytomegalovirus. Topics covered include the history of human cytomegaloviruses, techniques to culture and grow the virus in model cell types, the use of primary cells for the study of human cytomegalovirus pathogenesis, modern molecular techniques for assessing the biological consequences of viral infection, animal models for study of cytomegalovirus replication and numerous other topics of current interest. Written in the successful Methods in Molecular Biology series format, each chapter includes an introduction, list of necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.   Authoritative and easily accessible, Human Cytomegaloviruses: Methods and Protocols serves as a tool for basic scientists as well as clinical scientists with an interest in the basic fundamental aspects of viral gene expression and specific aspects of viral pathogenesis. .

Emerging infectious diseases. --- Medical virology. --- Infectious Diseases. --- Virology. --- Medical microbiology --- Virology --- Virus diseases --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases

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Herpes Simplex Virus: Methods and Protocols provides a wide collection of protocols employed in various levels of herpes virus research, including basic protocols on growing viruses in cell culture and cloning, manipulating, and preparing viral DNA. Other chapters describe approaches to design and apply HSV-1 vectors for vaccination, cancer and gene therapy, or to study specific aspects of HSV-1 biology such as latency, intracellular transport, and protein-protein interaction. Procedures for structural analyses, microscopy, proteomics, and testing of antivirals are included as well.  Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.   Practical and authoritative, Herpes Simplex Virus: Methods and Protocols will aid new researchers in the field of herpes virology as well as those experienced investigators wishing to embark on new techniques.

Emerging infectious diseases. --- Medical virology. --- Infectious Diseases. --- Virology. --- Medical microbiology --- Virology --- Virus diseases --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases

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This clinically oriented book covers selected infections of the central nervous system which are of considerable current interest. Aspects that are less well documented, such as spinal cord infections, central nervous system infections in patients with cancer, tropical infections, healthcare-associated ventriculitis or meningitis, and immunological problems in the international traveler are also discussed, as these are all problems relevant to daily practice.   CNS Infections: A Clinical Approach is of value to the busy clinician; the neurological international community as well as all primary care doctors, internal medicine specialists, and residents who take care of patients with suspected neurological infections. .

Central nervous system --- Infections. --- Neurology. --- Emerging infectious diseases. --- Internal medicine. --- Infectious Diseases. --- Internal Medicine. --- Medicine, Internal --- Medicine --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Nervous system --- Neuropsychiatry --- Diseases --- Neurology . --- Infectious diseases.

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This volume explores the nexus of manifestations of hematopathology and dermatopathology and provides a novel compartmental(epidermal, dermal, subcutaneous) -based framework to approach a diagnosis that considers both pseudolymphomatous and lymphomatous patterns. Through photographs, tables, and text, the book illustrates the range of non-neoplastic hematologic disorders and their neoplastic counterparts in skin: reactive patterns of infectious etiology and immune responses that simulate cutaneous lymphomas. The epidemiology, pathobiology, clinical and immuno-histopathologic manifestations in skin as well as the approach to diagnosis, selection and algorithmic interpretation of tests, and prognosis are also described.   Written by experts in the field, Cutaneous Hematopathology: Approach to the Diagnosis of Atypical Lymphoid-Hematopoietic Infiltrates in Skin is a comprehensive resource that is of great value to surgical pathologists, hematopathologists, dermatopathologists, residents and fellows, community dermatologists, oncologists and infectious disease practitioners.

Skin --- Diseases --- Diagnosis. --- Pathology. --- Dermatology. --- Emerging infectious diseases. --- Infectious Diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Medicine --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive --- Infectious diseases.

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This book provides a survey of recent advances in the development of antibiofilm agents for clinical and environmental applications. The fact that microbes exist in structured communities called biofilms has slowly become accepted within the medical community. We now know that over 80% of all infectious diseases are biofilm-related; however, significant challenges still lie in our ability to diagnose and treat these extremely recalcitrant infections. Written by experts from around the globe, this book offers a valuable resource for medical professionals seeking to treat biofilm-related disease, academic and industry researchers interested in drug discovery, and instructors who teach courses on microbial pathogenesis and medical microbiology.

Biofilms. --- Microbial aggregation --- Microbial ecology --- Microbiology. --- Emerging infectious diseases. --- Medical Microbiology. --- Infectious Diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Microbial biology --- Biology --- Microorganisms --- Medical microbiology. --- Infectious diseases.