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Gene expression --- Genes --- Genetic regulation --- Expression
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Epigenetik untersucht Fragestellungen, die auf der Schwelle zwischen Theorien kultureller Übertragung und biologischer Vererbung angesiedelt sind - und fordert damit eine neue interdisziplinäre Debatte heraus. Die Beitragenden aus Biochemie, Bioinformatik, Genetik, Medizin, Neurowissenschaft, Psychologie, Philosophie, Ethnologie, Kultur- und Literaturwissenschaften, Wissenssoziologie und Wissenschaftsgeschichte stellen sich systematisch den aus der Epigenetik hervorgehenden Herausforderungen. Wie ist aktuell das Verhältnis zwischen Kultur und Natur, zwischen Tradierung, Übertragung und Vererbung zu bestimmen?
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Expression. --- Literatur, Rhetorik, Literaturwissenschaft. --- English language -- Rhetoric. --- Expression.
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Censorship in varying forms has been part of human experience for 2,500 years and has proved itself to be a recurring presence for political thought, whether as active repression, a shaping context for expression, or as itself a subject for analysis and argument. From the death of Socrates to the fatwa against Salman Rushdie, attempts to silence thinkers and writers have provoked passionate and often penetrating responses that speak of their historical moment. Censorship Moments will provide short, accessible and stimulating access to a variety of these responses. Each chapter will couple a short textual 'moment' of writing on censorship and freedom of expression by a past writer with analysis by an expert current scholar. The book's main focus is the public political dimension of censorship, in its relation to political authority and political thought, while also reflecting on the porous boundary to literature and other areas such as law and the media.
Freedom of expression. --- Censorship --- History. --- Expression, Freedom of --- Free expression --- Liberty of expression --- Civil rights --- Book history --- Human rights
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Since the discovery regarding interference phenomenon, 20 years ago, RNA interference became standard method to suppress a gene expression into in vitro tests. Nowadays, the point of interest lies in vivo studies. The RNAi could be used as strong tool in specific therapy going from viral infection to cancer, if only the RNAi would have a proper structure. The main obstacle to RNAi potential therapeutic action is due to a difficulty small interfering RNA (siRNA) at the level of its action in vivo. An effective delivery strategy of siRNA must consider some limitations: (i) poor stability, (ii) undesirable non-specific immune response, (iii) a distribution in non-targeted tissues. The development of such a strategy requires a careful understanding of all the mechanisms of action of RNAi, engineering developed to overcome barriers to the delivery of siRNA, the site of action, and finally a clinical trial. This analysis allows us to offer a perspective on the therapeutic use of siRNA in human.
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Que nous révélaient les mouvements de langue de Hollande lors du débat qui l'opposait à Nicolas Sarkozy ? Comment interpréter les démangeaisons de Rafael Nadal ou de Laurent Blanc lors d'événements sportifs à enjeu ? Que nous apprennent les mouvements de sourcil de Jean Dujardin ? Coach en communication, synergologue, Stephen Bunard intervient régulièrement dans les médias pour analyser les gestes de politiques, patrons et sportifs. Il nous initie ici à l'art de cerner la vraie personnalité et les intentions véritables de ceux qui occupent la scène médiatique, mais aussi, à travers eux de nos interlocuteurs les plus divers. L'objectif ? Développer votre regard, ne rien laisser vous échapper, pour mieux interagir grâce à ce que vous décrypter.
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